Stent including anti-migration capabilities

Patent metadata

Field	Value
Publication number	US-11896474-B2
Application number	US-202217573754-A
Country	US
Kind code	B2
Filing date	Jan 12, 2022
Priority date	Nov 9, 2016
Publication date	Feb 13, 2024
Grant date	Feb 13, 2024

Abstract

An example medical device for treating a body lumen is disclosed. The medical device includes an expandable scaffold including first and second regions, each of the first and second regions include a plurality of interstices located therein. The medical device also includes a covering spanning each of the plurality of interstices of the first region. The second region is free of the covering. A biodegradable gripping material is disposed on an outer surface of the covering. Further, the expandable scaffold is configured to shift from a collapsed state to an expanded state and the second region is configured to contact an inner surface of the body lumen in the expanded state. Additionally, the gripping material is designed to initially prevent migration of the expandable scaffold upon implantation in the body lumen until the second region is secured to the inner surface of the body lumen.

First claim

What is claimed is:

1. A medical device for treating a body lumen, comprising:
an expandable scaffold;
a biostable covering spanning a first portion of the expandable scaffold, the biostable covering including an outer surface; and
a biodegradable gripping material having a roughened outer surface adapted to initially resist post-implantation migration disposed on at least a region of the outer surface of the biostable covering.

2. The medical device of claim 1 , wherein the roughened outer surface of the biodegradable gripping material has a surface roughness value of about 0.5 micrometers (μm) to about 2.5 μm.

3. The medical device of claim 1 , wherein the biodegradable gripping material includes a desiccant.

4. The medical device of claim 1 , wherein the expandable scaffold further includes a second portion that is devoid of the biostable covering.

5. The medical device of claim 4 , wherein the expandable scaffold is configured to shift from a collapsed state to an expanded state, and when in the expanded state, the gripping material is designed to initially prevent migration of the expandable scaffold in the body lumen until the second portion of the expandable scaffold becomes secured to the inner surface of the body lumen via tissue ingrowth.

6. The medical device of claim 5 , wherein the biodegradable gripping material is configured to degrade over a first time period.

7. The medical device of claim 6 , wherein the securement of the second portion of the expandable scaffold to the inner surface of the body lumen occurs over a second time period.

8. The medical device of claim 7 , wherein the second time period is less than the first time period.

9. The medical device of claim 7 , wherein the second time period overlaps with the first time period.

10. The medical device of claim 7 , wherein the second time period is between 4 to 18 days.

11. The medical device of claim 4 , further comprising:
an endothelializing material disposed on the second portion of the expandable scaffold.

12. The medical device of claim 1 , wherein the biostable covering is adapted to provide a pathway for food to travel through.

13. The medical device of claim 12 , wherein the biostable covering encapsulates the first portion of the expandable scaffold.

14. The medical device of claim 1 , wherein the expandable scaffold has a longitudinal axis and a length along the longitudinal axis and wherein the first portion has a length which is between 85 to 95 percent of the length of the expandable scaffold.

15. A medical device for treating a body lumen, comprising:
an expandable scaffold having a first portion and a second portion, the second portion having a flared profile;
a biostable covering spanning the first portion of the expandable scaffold, the biostable covering including an outer surface; and
a biodegradable gripping material having a roughened outer surface adapted to initially resist post-implantation migration disposed on at least a region of the outer surface of the biostable covering.

16. The medical device of claim 15 , wherein the expandable scaffold further comprises a third portion having a flared profile, with the first portion disposed between the first portion and the third portion.

17. The medical device of claim 15 , wherein the roughened outer surface has a surface roughness value of about 0.5 micrometers (μm) to about 2.5 μm.

18. A medical device for treating a body lumen, comprising:
an expandable scaffold including a first portion and a second portion;
a biostable covering spanning the first portion; and
a biodegradable gripping material disposed on at least a portion of an outer surface of the biostable covering;
wherein the biodegradable gripping material includes a desiccant configured to dry up a lubricious mucus-like inner surface of the body lumen.

19. The medical device of claim 18 , wherein the expandable scaffold is configured to shift from a collapsed state to an expanded state in which the second portion contacts the inner surface of the body lumen to promote tissue ingrowth therein;
wherein the gripping material is designed to initially prevent migration of the expandable scaffold upon implantation in the body lumen until the second portion is secured to the inner surface of the body lumen via the tissue ingrowth.

20. The medical device of claim 18 , wherein the gripping material includes a roughened outer surface having a surface roughness value of about 0.5 micrometers (μm) to about 2.5 μm.

Assignees

• Boston Scient Scimed Inc

Inventors

• Hynes Martin
• Folan Martyn G
• Wulfman David R
• Keating Thomas M
• MONTAGUE Matthew
• Nolan Damien V

Classifications

• A61F2/0077 Primary

  Special surfaces of prostheses, e.g. for improving ingrowth (A61F2/30767 takes precedence) · CPC title

• A61F2/07

  Stent-grafts · CPC title

• A61F2/90

  characterised by a net-like or mesh-like structure · CPC title

• A61F2002/044

  Oesophagi or esophagi or gullets · CPC title

• A61F2002/045

  Stomach, intestines · CPC title