Retaining mechanisms for prosthetic valves

Patent metadata

Field	Value
Publication number	US-11890187-B2
Application number	US-202016784981-A
Country	US
Kind code	B2
Filing date	Feb 7, 2020
Priority date	Mar 5, 2010
Publication date	Feb 6, 2024
Grant date	Feb 6, 2024

Abstract

Methods, apparatus, and systems used to deliver a prosthetic heart valve to a deficient valve are provided. For example, a support member is positioned to at least partially surround the native leaflets of a valve. A locking member is used to couple both ends of the support member, forming a support band. An expandable prosthetic heart valve is delivered into the native heart valve and expanded while the expandable prosthetic valve is at least partially within the support band, thereby causing one or more of the native leaflets of the native heart valve to be frictionally secured between the support band and the expanded prosthetic heart valve.

First claim

What is claimed is:

1. An assembly comprising:
a delivery catheter having a distal end;
a guidewire configured to extend distally through the delivery catheter and beyond the distal end of the delivery catheter such that the guidewire can form at least a partial loop around a patient's native mitral valve leaflets;
a support member configured to be advanced over the guidewire, wherein the support member comprises a first end portion, a second end portion, and a longitudinally extending linking portion between the first end portion and the second end portion, wherein the first end portion comprises a locking member configured to mate with the second end portion to form a closed annular band that is configured to be implantable entirely within a left ventricle of the patient; and
a prosthetic heart valve that is deployable within the native mitral valve leaflets such that the native mitral valve leaflets are positioned between and engaged by the annular band and the prosthetic heart valve.

2. The assembly of claim 1 , wherein the guidewire has a precurved portion that is biased to return to a predetermined curved configuration when it is advanced beyond the distal end of the delivery catheter, the predetermined curved configuration configured to curve around the native mitral valves to form at least a partial loop around the mitral valves.

3. The assembly of claim 1 , further comprising a precurved catheter configured to extend through a lumen of the delivery catheter, the precurved catheter comprising a precurved distal end portion that is biased to return to a predetermined curved configuration when it is advanced out of an opening in the delivery catheter, the precurved catheter comprising a lumen configured to receive the guidewire such that the guidewire can be advanced through the precurved catheter and the delivery catheter.

4. The assembly of claim 1 , further comprising a snare configured to capture a distal end portion of the guidewire.

5. The assembly of claim 4 , wherein the snare is further configured to pull the distal end portion of the guidewire back through the delivery catheter.

6. The assembly of claim 1 , further comprising an elongated pusher member configured to push the support member over the guidewire.

7. The assembly of claim 1 , wherein the delivery catheter is configured to be advanced through the patient's aortic arch toward the heart.

8. The assembly of claim 2 , wherein the prosthetic heart valve comprises an annular frame that is radially collapsible and expandable between a radially collapsed configuration and a radially expanded configuration; and
wherein the assembly further comprises a valve-delivery catheter configured to deliver the prosthetic heart valve into the patient's heart with the prosthetic heart valve in the radially collapsed configuration on a distal end portion of the valve-delivery catheter and deploy the prosthetic heart valve to the radially expanded configuration within the native mitral valve.

9. The assembly of claim 8 , wherein the valve-delivery catheter is configured to be inserted transapically into the left ventricle.

10. An assembly comprising:
a first delivery catheter having a distal end;
a guidewire configured to extend distally through the first delivery catheter and beyond the distal end of the first delivery catheter such that the guidewire can form at least a partial loop around the native mitral valve leaflets;
a support member comprising a first end portion, a second end portion, and a longitudinally extending linking portion between the first end portion and the second end portion, wherein the support member is configured to be advanced over the guidewire and around the native mitral valve leaflets, wherein the first end portion comprises a locking member configured to mate with the second end portion to form an annular band encircling the native mitral valve leaflets;
a prosthetic heart valve comprising an annular frame that is radially collapsible and expandable between a radially collapsed configuration and a radially expanded configuration, and a valve structure positioned within the frame; and
a second delivery catheter configured to deliver the prosthetic heart valve into the patient's heart with the prosthetic heart valve in the radially collapsed configuration on a distal end portion of the second delivery catheter and deploy the prosthetic heart valve to the radially expanded configuration within the native mitral valve such that the native mitral valve leaflets are positioned between and engaged by the annular band and the prosthetic heart valve.

11. The assembly of claim 10 , wherein the guidewire has a precurved portion that is biased to return to a predetermined curved configuration when it is advanced beyond the distal end of the first delivery catheter, the predetermined curved configuration configured to curve around the native mitral valves to form at least a partial loop around the mitral valves.

12. The assembly of claim 10 , further comprising a precurved catheter configured to extend through a lumen of the first delivery catheter, the precurved catheter comprising a precurved distal end portion that is biased to return to a predetermined curved configuration when it is advanced out of an opening in the first delivery catheter, the precurved catheter comprising a lumen configured to receive the guidewire such that the guidewire can be advanced through the precurved catheter and the first delivery catheter.

13. The assembly of claim 10 , further comprising a snare configured to capture a distal end portion of the guidewire.

14. The assembly of claim 13 , wherein the snare is further configured to pull the distal end portion of the guidewire back through the first delivery catheter.

15. The assembly of claim 10 , further comprising an elongated pusher member configured to push the support member over the guidewire.

16. The assembly of claim 10 , wherein the locking member and the second end portion of the support member are configured to have a complementary mating configuration.

17. An assembly comprising:
a delivery catheter having a distal end;
a guidewire configured to extend distally through the delivery catheter and beyond the distal end of the delivery catheter such that the guidewire can form at least a partial loop around a patient's native mitral valve leaflets;
a support member configured to be advanced over the guidewire, wherein the support member comprises a first end portion, a second end portion, and a longitudinally extending linking portion between the first end portion and the second end portion, wherein the first end portion comprises a locking member configured to mate with the second end portion to form an annular band;
a precurved catheter configured to extend through a lumen of the delivery catheter, the precurved catheter comprising a precurved distal end portion that is biased to return to a predetermined curved configuration when it is advanced out of an opening in the delivery catheter, the precurved catheter comprising a lumen configured to receive the guidewire such that the guidewire can be advanced through the precurved catheter and the delivery catheter; and
a snare configured to capture a distal end portion of the guidewire.

18. The assembly of claim 17 , further comprising an elongated pusher member configured to push the support member over the guidewire.

19. The assembly of claim 17 , further comprising:
a prosthetic heart valve that is deployable within the native mitral valve leaflets such that the native

Assignees

• Edwards Lifesciences Corp

Inventors

• Meiri Oded
• Levi Tamir S
• Witzman Ofir

Classifications

• A61F2/2409 Primary

  Support rings therefor, e.g. for connecting valves to tissue (annuloplasty rings A61F2/2442) · CPC title

• A61B17/0487 Primary

  Suture clamps, clips or locks, e.g. for replacing suture knots; Instruments for applying or removing suture clamps, clips or locks (suture anchors A61B17/0401; wound clamps or clips A61B17/08; ligaturing clamps or clips A61B17/122) · CPC title

• A61B17/122

  Clamps or clips, e.g. for the umbilical cord {(for the vas deferens A61F6/206)} · CPC title

• A61B17/12013

  for use in minimally invasive surgery, e.g. endoscopic surgery · CPC title

• A61B17/1227

  Spring clips · CPC title