Compositions and methods for treating the eye

US11878042B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-11878042-B2
Application numberUS-202217737513-A
CountryUS
Kind codeB2
Filing dateMay 5, 2022
Priority dateJul 27, 2018
Publication dateJan 23, 2024
Grant dateJan 23, 2024

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present invention relates to compositions comprising one or more compounds and/or extracts which induce, promote and/or improve production/release/delivery/excretion of mucin from and/or in the cornea, and methods of using the compositions to treat the eye.

First claim

Opening claim text (preview).

What is claimed is: 1. A method for producing/releasing/delivering/excreting mucin from and/or in the cornea comprising the step of administering a composition comprising: i) one or more extracts of the genus Pichia ; and ii) optionally, an ophthalmologically acceptable carrier. 2. The method according to claim 1 , wherein the extract is of a species selected from the group consisting of Pichia anomala, Pichia guilliermondii, Pichia norvegensis, Pichia ohmeri , and mixtures thereof. 3. The method according to claim 1 , wherein the extract is of Pichia anomala. 4. A method for maintaining the concentration of mucin-5AC (MUC5AC) in tears within the range of equal to or greater than 8 nanograms to 15 nanograms per milligrams of protein, comprising the step of administering a composition comprising: i) one or more extracts of the genus Pichia ; and ii) optionally, an ophthalmologically acceptable carrier. 5. A method for treating a patient having decreased or low-level production/release/delivery/excretion of mucin from and/or in the cornea comprising the step of topically administering to the eye the patient a composition comprising: i) one or more extracts of the genus Pichia ; and ii) optionally, an ophthalmologically acceptable carrier. 6. A method for promoting healing or increasing the rate of healing of wounds in and/or on the eye of a patient, comprising the step of administering compositions, comprising: i) one or more extracts of the genus Pichia ; and ii) optionally, an ophthalmologically acceptable carrier. 7. A method for improving the antimicrobial properties in tears of a patient, comprising the step of administering compositions, comprising: i) one or more extracts of the genus Pichia ; and ii) optionally, an ophthalmologically acceptable carrier.

Assignees

Inventors

Classifications

  • A61K36/064Primary

    Saccharomycetales, e.g. baker's yeast · CPC title

  • A61K9/0048Primary

    Eye, e.g. artificial tears · CPC title

  • Inorganic compounds · CPC title

  • Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers · CPC title

  • Carboxylic acids; Salts or anhydrides thereof · CPC title

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Frequently asked questions

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What does patent US11878042B2 cover?
The present invention relates to compositions comprising one or more compounds and/or extracts which induce, promote and/or improve production/release/delivery/excretion of mucin from and/or in the cornea, and methods of using the compositions to treat the eye.
Who is the assignee on this patent?
Johnson & Johnson Surgical Vision Inc
What technology area does this patent fall under?
Primary CPC classification A61K36/064. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Jan 23 2024 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 7 related publications on this page (citations in our corpus or others sharing the same primary CPC).