Activity levels for diffusing alpha-emitter radiation therapy
US-12070620-B2 · Aug 27, 2024 · US
US11872409B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11872409-B2 |
| Application number | US-202117925838-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 27, 2021 |
| Priority date | Nov 12, 2020 |
| Publication date | Jan 16, 2024 |
| Grant date | Jan 16, 2024 |
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A template assembly including a first grid ( 22 ) for placement on a first side of a body organ, defining a plurality of apertures ( 329 ) adapted to receive elongate applicators ( 410 ), a second grid ( 24 ) for placement on a second side of a body organ, defining a plurality of apertures ( 34 ), adapted to receive applicators passing through apertures of the first grid and the body organ and at least one frame ( 26 ) defining a large hole ( 72 ), positioned between the first and second grids and configured to grasp the body organ.
Opening claim text (preview).
The invention claimed is: 1. A template assembly, comprising: a first grid for placement on a first side of a body organ, defining a first plurality of apertures adapted to receive elongate applicators; a second grid for placement on a second side of the body organ, defining a second plurality of apertures, adapted to receive applicators passing through the first plurality of apertures of the first grid and the body organ; and at least one closed frame defining an internal large hole, positioned between the first and second grids, such that applicators passing through the first plurality of apertures and the body organ also pass through the internal large hole, and wherein the at least one closed frame is configured to grasp the body organ. 2. The template assembly of claim 1 , further comprising a bar on which the first grid, the second grid and the at least one closed frame are mounted. 3. The template assembly of claim 2 , wherein the second grid is removably mounted on the bar. 4. The template assembly of claim 2 , wherein the at least one closed frame is removably mounted on the bar. 5. The template assembly of claim 2 , wherein the at least one frame is slidably mounted on the bar. 6. The template assembly of claim 1 , wherein the large hole covers at least 25% of an area of the at least one closed frame. 7. The template assembly of claim 1 , wherein the large hole covers at least 50% of an area of the at least one closed frame. 8. The template assembly of claim 1 , wherein the at least one closed frame is coupled to the first grid through a first bridge and to the second grid through a second bridge, separate from the first bridge. 9. The template assembly of claim 1 , wherein the at least one closed frame is configured to grasp the body organ, between the at least one closed frame and one of the first and second grids. 10. The template assembly of claim 1 , wherein the at least one frame comprises a first frame and a second frame, each defining a large hole, wherein the first and second frames are positioned between the first and second grids, and wherein the body organ is grasped between the first frame and the second frame. 11. The template assembly of claim 1 , wherein the applicators passing through the first plurality of apertures and received by the second plurality of apertures pass through the large hole. 12. A template assembly, comprising: a first grid for placement on a first side of a body organ, defining a first plurality of apertures adapted to receive elongate applicators; a second grid for placement on a second side of the body organ, defining a second plurality of apertures, adapted to receive applicators passing through the first plurality of apertures of the first grid and the body organ; and at least one frame defining a large hole, positioned between the first and second grids and configured to grasp the body organ, wherein the first and second grids and the at least one frame have a triangular shape. 13. A template assembly, comprising: a first grid for placement on a first side of a body organ, defining a first plurality of apertures adapted to receive elongate applicators; a second grid for placement on a second side of the body organ, defining a second plurality of apertures, adapted to receive applicators passing through the first plurality of apertures of the first grid and the body organ; and a frame defining a large hole, positioned between the first and second grids and configured to grasp the body organ, between the frame and one of the first and second grids. 14. The template assembly of claim 13 , wherein the at least one frame comprises an open frame. 15. The template assembly of claim 13 , further comprising a bar on which the first grid, the second grid and the frame are mounted. 16. The template assembly of claim 15 , wherein the at least one frame is slidably mounted on the bar. 17. The template assembly of claim 13 , wherein the frame and the one of the first and second grids, grasp the organ from opposite sides of the body organ. 18. The template assembly of claim 13 , wherein the large hole defined by the frame allows a physician access to the body organ.
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