Method and system for providing continuous calibration of implantable analyte sensors

Patent metadata

Field	Value
Publication number	US-11872039-B2
Application number	US-201816181075-A
Country	US
Kind code	B2
Filing date	Nov 5, 2018
Priority date	Feb 28, 2006
Publication date	Jan 16, 2024
Grant date	Jan 16, 2024

Abstract

Method and system for providing continuous calibration of analyte sensors includes calibrating a first sensor, receiving data associated with detected analyte levels from the first sensor, and calibrating a second sensor based on a predetermined scaling factor and data associated with detected analyte levels from the first sensor, is disclosed.

First claim

What is claimed is:

1. A method, comprising:
receiving data from a first sensor and data from a second sensor substantially simultaneously, the first and second sensors both configured to be positioned in fluid contact with bodily fluid under a skin surface;
determining a correlation level between the data from the first sensor and the data from the second sensor;
determining that the correlation level is above a predetermined threshold;
in response to determining that the correlation level between the data from the first sensor and the data from the second sensor is above the predetermined threshold, assigning a calibration associated with the first sensor to the second sensor by transferring a scaling factor associated with the first sensor to sensor electronics associated with the second sensor, wherein the scaling factor is selected to yield a lowest level of average error between the data from the first sensor and the data from the second sensor, wherein the scaling factor is determined by selecting the scaling factor from a group of predetermined scaling factors.

2. The method of claim 1 , further comprising positioning the second sensor in fluid contact with the bodily fluid after the first sensor is positioned in fluid contact with the bodily fluid.

3. The method of claim 1 , wherein the data from the first sensor and the data from the second sensor correspond to analyte levels in the bodily fluid.

4. The method of claim 3 , wherein the correlation level comprises a measure for the degree of correspondence between the analyte levels corresponding to the data from the first sensor and the analyte levels corresponding to the data from the second sensor over a period of time.

5. The method of claim 1 , further comprising calibrating the second sensor using the data from the first sensor as a reference.

6. The method of claim 5 , wherein calibrating the second sensor is performed without a user-initiated reference measurement.

7. The method of claim 1 , furthering comprising calibrating the second sensor using the scaling factor and the data from the first sensor.

8. The method of claim 1 , wherein the data from the first sensor and the data from the second sensor are received over different kinds of communication links, the kinds of communication links selected from a list including a radio frequency link, a Bluetooth link, an infrared link, or a wired link.

9. The method of claim 1 , wherein the scaling factor is transferred from sensor electronics associated with the first sensor to the sensor electronics associated with the second sensor.

10. The method of claim 1 , wherein the data from the first sensor and the data from the second sensor is received after a stabilization period for the second sensor.

11. The method of claim 1 , further comprising determining a sensor sensitivity for the second sensor based on the scaling factor.

12. A system, comprising:
a first sensor and a second sensor both configured to be positioned in fluid contact with bodily fluid under a skin surface;
a first sensor electronics operatively coupled to the first sensor;
a second sensor electronics operatively coupled to the second sensor; and
a receiving device, comprising:
one or more processors; and
a memory storing instructions which, when executed by the one or more processors, cause the one or more processors to:
substantially simultaneously receive data from the first sensor and the second sensor;
determine a correlation level between the data from the first sensor and the data from the second sensor;
determine that the correlation level is above a predetermined threshold;
in response to determining that the correlation level between the data from the first sensor and the data from the second sensor is above the predetermined threshold, assign a calibration associated with the first sensor to the second sensor by transferring a scaling factor associated with the first sensor to the second sensor electronics, wherein the scaling factor is selected to yield a lowest level of error between the data from the first sensor and the data from the second sensor, wherein the scaling factor is determined by selecting the scaling factor from a group of predetermined scaling factors.

13. The system of claim 12 , wherein the second sensor is positioned in fluid contact with the bodily fluid after the first sensor is positioned in fluid contact with the bodily fluid.

14. The system of claim 12 , wherein the data from the first sensor and the data from the second sensor correspond to analyte levels in the bodily fluid.

15. The system of claim 14 , wherein the correlation level comprises a measure for the degree of correspondence between the analyte levels corresponding to the data from the first sensor and the analyte levels corresponding to the data from the second sensor over a period of time.

16. The system of claim 12 , the memory storing instructions to calibrate the second sensor using the data from the first sensor as a reference.

17. The system of claim 16 , the memory storing instructions to calibrate the second sensor without a user-initiated reference measurement.

18. The system of claim 12 , the memory storing instructions to calibrate the second sensor using the scaling factor and the data from the first sensor.

19. The system of claim 18 , wherein the scaling factor is transferred from sensor electronics associated with the first sensor to the sensor electronics associated with the second sensor.

20. The system of claim 12 , wherein the data from the first sensor and the data from the second sensor are received over different kinds of communication links, the kinds of communication links selected from a list including a radio frequency link, a Bluetooth link, an infrared link or a wired link.

21. The system of claim 12 , wherein the data from the first sensor and the data from the second sensor is received after a stabilization period for the sensor.

22. The system of claim 12 , the memory storing instructions to determine a sensor sensitivity for the second sensor based on the scaling factor.

Assignees

• Abbott Diabetes Care Inc

Inventors

• Feldman Benjamin Jay

Classifications

• A61B5/1495 Primary

  Calibrating or testing of in-vivo probes · CPC title

• A61B5/0017

  transmitting optical signals · CPC title

• A61B5/0024

  for multiple sensor units attached to the patient, e.g. using a body or personal area network · CPC title

• A61B5/0031 Primary

  Implanted circuitry · CPC title

• A61B5/14503

  invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors (A61B5/1459, A61B5/1464, A61B5/1473, A61B5/1482, A61B5/14865 take precedence) · CPC title