HSP90-targeted inflammation and infection imaging and therapy
US-11065350-B2 · Jul 20, 2021 · US
US11857352B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11857352-B2 |
| Application number | US-201716330679-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 6, 2017 |
| Priority date | Sep 6, 2016 |
| Publication date | Jan 2, 2024 |
| Grant date | Jan 2, 2024 |
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The present invention provides a composition comprising the compound having the structure: or a salt of the compound; 4-amino-2-[ 19 F]-fluorobenzoic acid or a salt of 4-amino-2-[ 19 F]-fluorobenzoic acid; and at least one acceptable carrier.
Opening claim text (preview).
What is claimed is: 1. A composition comprising the compound having the structure: or a salt of the compound; 4-amino-2-[ 19 F]-fluorobenzoic acid or a salt of 4-amino-2-[ 19 F]-fluorobenzoic acid; and at least one acceptable carrier, wherein the ratio of the 4-amino-2-[ 18 F]-flurobenzoic acid to the 4-amino-2-[ 19 F]-flurobenzoic acid is in the range from 1:90 to 1:550. 2. The composition of claim 1 , wherein the ratio of the 4-amino-2-[ 18 F]-fluorobenzoic acid to the 4-amino-2-[ 19 F]-fluorobenzoic acid is in a range from 1:324 to 1:500. 3. The composition of claim 1 , wherein the ratio of the 4-amino-2-[ 18 F]-fluorobenzoic acid to the 4-amino-2-[ 19 F]-fluorobenzoic acid is in a range from 1:99 to 1:324. 4. The composition of claim 1 , wherein the radiochemical purity of 4-amino-2-[ 18 F]-fluorobenzoic acid is at least 95%. 5. The composition of claim 1 , wherein the ratio of the 4-amino-2-[ 18 F]-fluorobenzoic acid to the 4-amino-2-[ 19 F]-fluorobenzoic acid is in a range from 1:99 to 1:500.
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