Flexible hexagonal boron nitride composites for additive manufacturing applications

Patent metadata

Field	Value
Publication number	US-11850327-B2
Application number	US-201917049281-A
Country	US
Kind code	B2
Filing date	Apr 30, 2019
Priority date	Apr 30, 2018
Publication date	Dec 26, 2023
Grant date	Dec 26, 2023

Abstract

Thermal management composites and scaffolds for heat-generating implantable electronic devices made from the thermal management composites are provided. The composite materials are cytocompatible, porous materials that include hexagonal boron nitride particles dispersed in an elastomeric polymer binder.

First claim

What is claimed is:

1. A biocompatible device comprising:
an implantable electronic device; and
a thermally conductive, electrically insulating scaffold around at least a portion of the implantable electronic device, the scaffold comprising continuous flexible fibers of a cytocompatible composite, the cytocompatible composite comprising:
a biocompatible elastomeric polymer binder; and
hexagonal boron nitride particles dispersed in the biocompatible elastomeric polymer binder.

2. The device of claim 1 , wherein the cytocompatible composite has a hexagonal boron nitride particle content in the range from 30 vol. % to 60 vol. %.

3. The device of claim 1 , wherein the cytocompatible composite has a hexagonal boron nitride particle content in the range from 35 vol. % to 45 vol. %.

4. The device of claim 1 , wherein the cytocompatible composite has a porosity in the range from 20% to 40%.

5. The device of claim 1 , wherein the cytocompatible composite has a porosity in the range from 20% to 35%.

6. The device of claim 2 , wherein the cytocompatible composite has a porosity in the range from 20% to 40%.

7. The device of claim 6 , wherein the biocompatible elastomeric polymer binder is poly(lactic-co-glycolic acid).

8. The device of claim 7 , wherein the cytocompatible composite has a thermal conductivity of at least 1.5 W/m-K.

9. The device of claim 1 , wherein the one or more fibers have a cross-sectional diameter in the range from 50 μm to 500 μm.

10. The device of claim 9 , wherein the one or more fibers have a circular or oval cross-section.

Assignees

• Univ Northwestern

Inventors

• Guiney Linda M
• Mansukhani Nikhita D
• Jakus Adam E
• Shah Ramille N
• Hersam Mark C

Classifications

• A61L27/446 Primary

  with other specific inorganic fillers other than those covered by A61L27/443 or A61L27/46 · CPC title

• A61L27/50

  Materials characterised by their function or physical properties {, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials} · CPC title

• A61M5/14276

  specially adapted for implantation · CPC title

• A61N1/37512

  Pacemakers · CPC title

• B33Y70/10

  Composites of different types of material, e.g. mixtures of ceramics and polymers or mixtures of metals and biomaterials · CPC title