1,2,3-triazole-4-amine derivatives for the treatment of sigma receptor related diseases and disorders
US-2015353510-A1 · Dec 10, 2015 · US
Reagent for mass spectrometry
US11845733B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11845733-B2 |
| Application number | US-202117155020-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 21, 2021 |
| Priority date | Jul 24, 2018 |
| Publication date | Dec 19, 2023 |
| Grant date | Dec 19, 2023 |
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- Title
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- Abstract
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Abstract
Official abstract text for this publication.
The present invention relates to reagents which are suitable to be used in mass spectrometry as well as methods of mass spectrometric determination of analyte molecules using said reagents.
First claim
Opening claim text (preview).
The invention claimed is: 1. A salt of a compound of formula A: X-L1-Y-L2-Z wherein X is a reactive unit, which is capable of forming a covalent bond with an analyte molecule, L1 and L2 are independently of each other substituted or unsubstituted linker, Y is a neutral loss unit, Z is a charged unit comprising at least one permanently charged moiety, wherein the reactive unit X is H2N—NH—, the neutral loss unit Y is triazole or tetrazole, and the charge unit Z comprises a piperidine unit, or a salt of the compound is selected from the group consisting of: 2. The salt of a compound of claim 1 , wherein the neutral loss unit releases a neutral entity upon ionization. 3. The salt of a compound of claim 1 , wherein the linker L1 and L2 independently of each other comprise 1 to 10 C-atoms. 4. A composition comprising the salt of a compound of claim 1 .
Assignees
Inventors
Classifications
- C07D249/06Primary
with aryl radicals directly attached to ring atoms · CPC title
not condensed with other rings · CPC title
- C07D249/04Primary
1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles · CPC title
Five-membered rings · CPC title
directly linked by a ring-member-to-ring-member bond · CPC title
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- What does patent US11845733B2 cover?
- The present invention relates to reagents which are suitable to be used in mass spectrometry as well as methods of mass spectrometric determination of analyte molecules using said reagents.
- Who is the assignee on this patent?
- Roche Diagnostics Operations Inc
- What technology area does this patent fall under?
- Primary CPC classification C07D249/06. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Dec 19 2023 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).