Method of inhibiting proliferation of tumor cell using triboelectric energy generator using ultrasonic wave

Patent metadata

Field	Value
Publication number	US-11844942-B2
Application number	US-202017104546-A
Country	US
Kind code	B2
Filing date	Nov 25, 2020
Priority date	Dec 10, 2019
Publication date	Dec 19, 2023
Grant date	Dec 19, 2023

Abstract

A triboelectric energy generator includes a substrate, a first triboelectric member disposed on the substrate in a first partial region of a top face of the substrate, a second triboelectric member disposed on the substrate in a second partial region of the top of the substrate, a third triboelectric member disposed above and spaced from the first triboelectric member and the second triboelectric member. The first triboelectric member, the second triboelectric member, and the third triboelectric member are made of different materials. When an ultrasonic wave is applied to a top face of the third triboelectric member, the third triboelectric member is constructed to alternately contact and non-contact both the first triboelectric member and the second triboelectric member, thereby to generate triboelectricity.

First claim

What is claimed is:

1. A triboelectric energy generator using ultrasonic wave, the generator comprising:
a substrate;
a first triboelectric member disposed on the substrate and in a first partial region of a top face of the substrate;
a second triboelectric member disposed on the substrate in a second partial region of the top of the substrate, wherein the second partial region is different from the first partial region; and
a third triboelectric member disposed above and spaced from the first triboelectric member and the second triboelectric member,
wherein the first triboelectric member, the second triboelectric member, and the third triboelectric member are made of different materials,
wherein the material of the third triboelectric member has a position between positions of the materials of the first triboelectric member and the second triboelectric member on a triboelectric series,
wherein, when an ultrasonic wave is applied to a top face of the third triboelectric member, the third triboelectric member is constructed to alternately contact and non-contact both of the first triboelectric member and the second triboelectric member, thereby to generate triboelectricity.

2. The triboelectric energy generator of claim 1 , wherein one of the first triboelectric member and the second triboelectric member is made of a material having a positively charged property on the triboelectric series, and other among the first triboelectric member and the second triboelectric member is made of a material having a negatively charged property on the triboelectric series.

3. The triboelectric energy generator of claim 1 , wherein the third triboelectric member is made of a polymer material.

4. The triboelectric energy generator of claim 1 , wherein a first electrode is disposed between the first triboelectric member and the substrate, and a second electrode is disposed between the second triboelectric member and the substrate.

5. The triboelectric energy generator of claim 1 , wherein the first triboelectric member and the second triboelectric member have the same thickness.

6. The triboelectric energy generator of claim 1 , wherein an area of the first partial region is equal to an area of the second partial region.

7. The triboelectric energy generator of claim 1 , wherein a first spacer is disposed between the first triboelectric member and the third triboelectric member, and a second spacer is disposed between the second triboelectric member and the third triboelectric member.

8. The triboelectric energy generator of claim 1 , wherein the energy generator is packaged.

9. An implantable tumor treatment device comprising:
the triboelectric energy generator of claim 1 ;
first and second wires respectively connected to the first triboelectric member and the second triboelectric member; and
first and second insulated electrodes respectively connected to distal ends of the first and second wires, and facing away each other.

10. The device of claim 9 , wherein a treatment target tumor cell is sandwiched between the first and second insulated electrodes, wherein an ultrasonic wave is applied from an outside of a body into the triboelectric energy generator embedded in the body to generate electricity to generate an electric field between the first and second insulated electrodes.

11. The device of claim 10 , wherein the applied ultrasonic wave has a frequency of 10 kHz to 1 MHz.

Assignees

• Research & Business Found Sungkyunkwan Univ

Inventors

• Kim Sangwoo
• Yoon Hong Joon
• Lee Dong Min
• Kim Young Jun
• Kim Ji Hye
• Kim Bo Sung
• Jung Jae Hwan
• Kang Dong Hyeon
• Kim Tae Hyeong

Classifications

• A61N1/36002 Primary

  Cancer treatment, e.g. tumour · CPC title

• A61N1/05

  for implantation or insertion into the body, e.g. heart electrode (A61N1/06 takes precedence) · CPC title

• A61N1/3787 Primary

  from an external energy source · CPC title

• H02N1/04

  Friction generators · CPC title

• A61B2018/00398

  Blood · CPC title