Alkenone-based formulations for topical applications

Patent metadata

Field	Value
Publication number	US-11839675-B2
Application number	US-202117397256-A
Country	US
Kind code	B2
Filing date	Aug 9, 2021
Priority date	Nov 16, 2015
Publication date	Dec 12, 2023
Grant date	Dec 12, 2023

Abstract

The use of long-chain alkenones to impart desired characteristics in personal care compositions for topical applications is described. The preparation of mixtures long-chain alkenones and synthetic derivatives thereof is presented. Examples of compositions include abrasive soaps, with alkenones serving as natural exfoliating agents. Alkenones and their derivatives can serve as emollients, occlusive agents, encapsulating agents, stabilizing agents, binding agents, thickening agents, surfactants, and antimicrobials.

First claim

The embodiments of the invention in which an exclusive property or privilege is claimed are defined as follows:

1. A personal care composition, comprising:
a compound of Formula (I):

wherein;
R 1 is methyl or ethyl; and
R 2 is a C 30-45 alkenyl having at least one trans double carbon-carbon bond, or R 2 is a C 30-45 alkyl;
provided that the compound of Formula (I) is not

wherein the composition does not comprise acylglycerols.

2. The personal care composition of claim 1 , wherein the composition does not comprise carotenoids and chlorophylls.

3. The personal care composition of claim 1 , wherein the composition does not comprise a total algae lipid extract.

4. The personal care composition of claim 1 , wherein the compound of Formula (I) is present in an amount of from 5% to 35% w/w of the composition.

5. The personal care composition of claim 1 , wherein R 2 is a C35-45 alkenyl having at least one trans double carbon-carbon bond.

6. The personal care composition of claim 1 , wherein R 2 has 2 to 4 trans double carbon-carbon bonds.

7. The personal care composition of claim 1 , further comprising a synthetic agent selected from synthetic solubilizing agents, synthetic emulsifying agents, synthetic humectants, synthetic emollients, synthetic occlusive agents, synthetic surfactants, synthetic preservatives, synthetic binding agents, synthetic thickeners, synthetic solvents, synthetic fragrances, and any combination thereof.

8. The personal care composition of claim 1 , further comprising a naturally occurring agent selected from natural emollients, natural occlusive agents, natural emulsifying agents, natural anti-oxidants, natural colorants, natural fragrances, and any combination thereof.

9. A personal care composition, comprising:
1 to 50% weight of a compound of Formula (I):

wherein
R 1 is methyl or ethyl; and
R 2 is a C 30-45 alkenyl having at least one trans double carbon-carbon bond, or R 2 is a C 30-45 alkyl;
provided that the compound of Formula (I) is not

wherein the composition does not comprise acylglycerols.

10. The personal care composition of claim 9 , wherein the composition does not comprise carotenoids and chlorophylls.

11. The personal care composition of claim 9 , wherein the composition does not comprise a total algae lipid extract.

12. The personal care composition of claim 9 , wherein the compound of Formula (I) is present in an amount of from 5% to 35% w/w of the composition.

13. The personal care composition of claim 9 , wherein R 2 is a C35-45 alkenyl having at least one trans double carbon-carbon bond.

14. The personal care composition of claim 9 , wherein R 2 has 2 to 4 trans double carbon-carbon bonds.

15. The personal care composition of claim 9 , further comprising a synthetic agent selected from synthetic solubilizing agents, synthetic emulsifying agents, synthetic humectants, synthetic emollients, synthetic occlusive agents, synthetic surfactants, synthetic preservatives, synthetic binding agents, synthetic thickeners, synthetic solvents, synthetic fragrances, and any combination thereof.

16. The personal care composition of claim 9 , further comprising a naturally occurring agent selected from natural emollients, natural occlusive agents, natural emulsifying agents, natural anti-oxidants, natural colorants, natural fragrances, and any combination thereof.

Assignees

• Woods Hole Oceanographic Inst
• Western Washington Univ

Inventors

• O'Neil Gregory W
• Reddy Christopher M

Classifications

• A61K8/33 Primary

  containing oxygen · CPC title

• A61K8/35

  Ketones, e.g. benzophenone · CPC title

• A61K8/361

  Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof · CPC title

• A61K8/37 Primary

  Esters of carboxylic acids · CPC title

• A61K8/416

  Quaternary ammonium compounds (A61K8/35 takes precedence) · CPC title