Neural interfacing device

Patent metadata

Field	Value
Publication number	US-11839478-B2
Application number	US-202117215193-A
Country	US
Kind code	B2
Filing date	Mar 29, 2021
Priority date	Feb 1, 2014
Publication date	Dec 12, 2023
Grant date	Dec 12, 2023

Abstract

A neural interfacing device is disclosed. The neural interfacing device includes a microneedle electrode. The microneedle electrode includes a body having a void formed therein and a plurality of microneedles. The void surrounds the plurality of microneedles, and the plurality of microneedles are bent outward with respect to the body to form a three-dimensional microneedle electrode. Additionally, each of the plurality of microneedles is sized and shaped to penetrate a nerve epineurium.

First claim

What is claimed is:

1. A neural interfacing device, comprising:
a microneedle electrode comprising a conductive body that comprises a plurality of microneedles, wherein the conductive body has a void formed therein, wherein the void surrounds the plurality of microneedles, wherein the plurality of microneedles are bent outward with respect to the conductive body to form a three-dimensional microneedle electrode, and wherein each of the plurality of microneedles is sized and shaped to penetrate a nerve epineurium.

2. The neural interfacing device of claim 1 , further comprising:
a planar base comprising an inner surface and an outer surface; and
wherein the microneedle electrode is fixed to the inner surface of the planar base.

3. The neural interfacing device of claim 1 , further comprising:
an elongate cuff comprising an outer surface and an inner surface and sized to fit at least partially around a nerve;
wherein the microneedle electrode is fixed to the inner surface of the elongate cuff; and
wherein the elongate cuff is configured to fit to the nerve.

4. The neural interfacing device of claim 1 , wherein each of the plurality of microneedles is sized and shaped to penetrate the nerve epineurium without any portion of the microneedle electrode penetrating any nerve axon beyond a depth of 500 micrometers.

5. The neural interfacing device of claim 1 , wherein each of the plurality of microneedles is sized and shaped to penetrate the nerve epineurium without any portion of the microneedle electrode penetrating any nerve axon.

6. The neural interfacing device of claim 1 , wherein when the microneedle electrode is applied to a nerve or bundle of nerves, the plurality of microneedles anchor the neural interfacing device with respect to the nerve or bundle of nerves.

7. The neural interfacing device of claim 6 , wherein the plurality of microneedles provide stability to the neural interfacing device such that it remains in position with respect to the nerve or bundle of nerves.

8. The neural interfacing device of claim 1 , wherein each of the plurality of microneedles has a height of about 10 micrometers to about 10 millimeters.

9. The neural interfacing device of claim 1 , wherein the conductive body is a metal pad.

10. The neural interfacing device of claim 1 , wherein the plurality of microneedles comprise between 2 and 1000 microneedles.

11. The neural interfacing device of claim 1 , wherein the neural interfacing device comprises at least two microneedle electrodes, wherein one of the at least two microneedle electrodes is the microneedle electrode.

12. The neural interfacing device of claim 1 , wherein the neural interfacing device comprises at least three microneedle electrodes, wherein one of the at least three microneedle electrodes is the microneedle electrode.

13. The neural interfacing device of claim 1 , wherein the neural interfacing device comprises an array of microneedle electrodes, wherein the array of microneedle electrodes includes the microneedle electrode.

14. The neural interfacing device of claim 13 , wherein the array of microneedle electrodes is a grid pattern having from 4 to 1000 microneedle electrodes.

15. The neural interfacing device of claim 1 , wherein the neural interfacing device is connected to stimulation electronics via electrical connectors.

16. The neural interfacing device of claim 1 , wherein the microneedle electrode is a single electrode.

17. The neural interfacing device of claim 1 , wherein the microneedle electrode is configured as a single channel for applying stimulus or receiving data.

18. The neural interfacing device of claim 1 , wherein the microneedle electrode is configured to monitor electrical signals within a nerve.

19. The neural interfacing device of claim 1 , wherein the microneedle electrode is configured to apply an electrical stimulus to a nerve.

Assignees

• Biocircuit Tech Inc
• Georgia Tech Res Inst
• Biocircuit Tech Inc Georgia Tech Research Corporation

Inventors

• Butera Robert J
• Patel Yogi A
• Ross James D
• Rajaraman Swaminathan
• Clements Isaac

Classifications

• A61B5/24

  Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof · CPC title

• A61B5/294 Primary

  for nerve conduction study [NCS] · CPC title

• A61B5/685 Primary

  Microneedles · CPC title

• A61B5/4041

  Evaluating nerves condition · CPC title

• A61B5/6877 Primary

  Nerve · CPC title