Methods, compounds, and compositions for the treatment of angiotensin-related diseases
US-9732074-B2 · Aug 15, 2017 · US
US11833148B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11833148-B2 |
| Application number | US-201917053984-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 10, 2019 |
| Priority date | May 11, 2018 |
| Publication date | Dec 5, 2023 |
| Grant date | Dec 5, 2023 |
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Disclosed herein are methods for treating or limiting development of cardiovascular disease-related neurological disorders by administering a compound of general formula (I), as defined herein.
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We claim: 1. A method for increasing cognitive function in a subject having a cardiovascular disease-related neurological disorder, comprising administering to the subject a pharmaceutical composition comprising a pharmaceutically acceptable carrier and an amount effective to increase the subject's cognitive function of a compound selected from compound 7 and compound 10: or a pharmaceutically acceptable salt thereof, and wherein the cardiovascular disease is left-ventricular hypertrophy, and wherein the cardiovascular disease-related neurological disorder is cognitive decline or Alzheimer's disease. 2. The method of claim 1 , wherein the cardiovascular disease-related neurological disorder is Alzheimer's. 3. The method of claim 1 , wherein the compound is compound 7.
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for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia · CPC title
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