Method for stabilizing retinoic acid precursors and a skin benefit composition with stabilized retinoic acid precursors

Patent metadata

Field	Value
Publication number	US-11826449-B2
Application number	US-202217713573-A
Country	US
Kind code	B2
Filing date	Apr 5, 2022
Priority date	May 12, 2016
Publication date	Nov 28, 2023
Grant date	Nov 28, 2023

Abstract

A method for stabilizing retinoic acid precursors and a skin benefit composition with stabilized retinoic acid precursors are described. The composition has a retinoic acid precursor and a resorcinol to impede oxidation of the precursor in situ in the composition.

First claim

The invention claimed is:

1. A composition comprising:
(a) a retinoic acid precursor selected from retinyl propionate, hydroxyanasatil retinoate, and mixtures thereof;
(b) a skin benefit agent selected from 4-ethyl resorcinol, 4-butyl resorcinol, 4-hexyl resorcinol, 4-isopropyl resorcinol and mixtures thereof;
(c) niacinamide; and
(d) a cosmetically acceptable carrier,

wherein the retinoic acid precursor and the skin benefit agent are present at a weight ratio of from about 1:2 to about 2:1.

2. The composition according to claim 1 , wherein the retinoic acid precursor is present from 0.001 to 10% by weight of the composition, and the skin benefit agent is present from 0.001 to 10% of the composition.

3. The composition according to claim 1 further comprising a retinoid booster selected from climbazole, bibonazole, farnesol, glycyrrhetinic acid, ursolic acid, geranyl geraniol, oleyl betaine, hexanoyl sphingosine, and mixtures thereof.

4. The composition according to claim 1 further comprises at least one component selected from creatine, 1,2-octanediol, sunscreen, conjugated linoleic acid, hydroxyl acid, 12-hydroxystearic acid, phenoxyethanol, glyceryl stearate, glycol stearate, stearamide AMP, PEG-100 stearate, cetyl alcohol, and mixtures thereof.

5. The composition according to claim 1 , wherein the composition is not an emulsion.

6. The composition according to claim 1 , wherein the composition is an oil-in-water emulsion.

7. The composition according to claim 1 , wherein the composition is an water-in-oil emulsion.

8. The composition according to claim 1 , wherein the skin benefit agent impedes oxidation of the retinoic acid precursor in the composition.

9. A method for impeding oxidation comprising a step of topically applying to skin the composition of claim 1 .

Assignees

• Conopco Inc

Inventors

• Lou Anjing
• Moaddel Teanoosh
• Patel Anil Babubhai

Classifications

• A61G19/00

  Hoisting or lowering devices for coffins · CPC title

• A61K8/347 Primary

  Phenols · CPC title

• A61K8/062

  Oil-in-water emulsions · CPC title

• A61K8/361

  Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof · CPC title

• A61Q19/00

  Preparations for care of the skin · CPC title