Embolic devices and methods of manufacturing same

Patent metadata

Field	Value
Publication number	US-11819217-B2
Application number	US-202016989532-A
Country	US
Kind code	B2
Filing date	Aug 10, 2020
Priority date	Dec 30, 2015
Publication date	Nov 21, 2023
Grant date	Nov 21, 2023

Abstract

A flat embolic braid having a first side comprising a first side surface, and a second side comprising a second side surface facing in an opposite direction than the first side surface, the braid having an elongated constrained configuration for being deployed through a delivery catheter, and a three-dimensional unconstrained configuration, wherein in the three-dimensional unconstrained configuration, the braid assumes a plurality of successive loops in which the braid is at least partially twisted between successive loops of the plurality, so that the first side surface faces externally of each loop, and the second side surface faces an interior of each loop, respectively, regardless of a change in direction and/or orientation of the braid.

First claim

What is claimed is:

1. An embolic device, comprising:
an elongate flat member having a longitudinal axis, a first side comprising a first side surface, and a second side comprising a second side surface, the first and second sides being reverse to each other with the first side surface and second side surface facing in opposite directions,
the elongate flat member having an elongated constrained configuration for being deployed through a delivery catheter to targeted vascular site, and a three-dimensional unconstrained configuration, the elongate flat member composed of a metal selected from the group consisting of: a Platinum Group metal, rhenium, tungsten, gold, silver and tantalum, and an alloy of any of the foregoing metals,
wherein in the three-dimensional unconstrained configuration, the elongate flat member assumes a plurality of successive loops in which the elongate flat member is at least partially twisted about the longitudinal axis of the elongate flat member between each loop of the plurality, so that the first side surface faces externally of each loop, and the second side surface faces an interior of each loop, respectively, regardless of a change in direction and/or orientation of the elongate flat member, and wherein loops that are directly adjacent to a first loop of the plurality have respective rotational axes which are angled to a rotational axis of the first loop by 65-95 degrees.

2. The embolic device of claim 1 , wherein the Platinum Group metal is selected from the group consisting of platinum, rhodium, and palladium, and wherein the alloys of the foregoing metals is selected from the group consisting of an alloy of platinum, an alloy of rhodium, an alloy of palladium, an alloy of rhenium, an alloy of tungsten, an alloy of gold, an alloy of silver, and an alloy of tantalum.

3. The embolic device of claim 1 , wherein the elongate flat member comprises a braided mesh formed of a plurality of filaments or wires.

4. The embolic device of claim 3 , wherein the filaments or wires are attached to each other or to a respective securing element at each of a proximal end and a distal end of the braided mesh.

5. The embolic device of claim 4 , wherein the filaments or wires are attached to each other via an adhesive at each of the proximal and distal ends of the braided mesh.

6. The embolic device of claim 4 , further comprising a respective coil coupled to at least one of the proximal and distal ends of the braided mesh.

7. The embolic device of claim 6 , wherein the respective coil(s) are composed of shape memory material and assume a plurality of successive loops when the braided mesh is in the three-dimensional unconstrained configuration.

8. The embolic device of claim 4 , wherein the securing element is selected from the group consisting of: a cap, and a non-traumatic tip.

9. The embolic device of claim 1 , wherein the three-dimensional unconstrained configuration is imparted on the elongate flat member by thermally treating the elongate flat member while the elongate flat member is wound in alternating directions about respective posts extending outwardly from a mandrel to thereby form the plurality of successive loops.

10. The embolic device of claim 1 , the plurality of successive loops comprising at least five successive loops.

11. An embolic device for occluding an aneurysm, the embolic device comprising:
an elongate flat braid formed out of one or more braided filaments or wires composed of a metal selected from the group consisting of: a Platinum Group metal, rhenium, tungsten, gold, silver and tantalum, and an alloy of any of the foregoing metals,
the elongate flat braid having a longitudinal axis, a first side comprising a first side surface, and a second side comprising a second side surface, the first and second sides being reverse to each other with the first side surface and second side surface facing in opposite directions,
the elongate flat braid having an elongated constrained configuration for being deployed through a delivery catheter into the aneurysm, and a three-dimensional unconstrained configuration after being deployed out of the delivery catheter within the aneurysm,
wherein in the three-dimensional unconstrained configuration, the elongate flat braid assumes a plurality of successive loops in which the elongate flat braid is at least partially twisted about the longitudinal axis of the elongate flat braid between each loop of the plurality, so that the first side surface faces externally of each loop towards an interior wall of the aneurysm, and the second side surface faces an interior of each loop, respectively, regardless of a change in direction and/or orientation of the elongate flat braid, wherein each loop defines a plane, and wherein loops that are directly adjacent to a first loop of the plurality have respective rotational axes which are angled to a rotational axis of the first loop by 65-95 degrees.

12. The embolic device of claim 11 , the one or more braided filaments or wires comprising a plurality of filaments or wires that are attached to each other at each of a proximal end and a distal end of the elongate flat braid, the embolic device further comprising a respective coil coupled to at least one of the proximal and distal ends of the elongate flat braid.

13. The embolic device of claim 12 , wherein the respective coil(s) are composed of shape memory material and assume a plurality of successive loops when the elongate flat braid is in the three-dimensional unconstrained configuration.

14. The embolic device of claim 12 , wherein the Platinum Group metal is selected from the group consisting of platinum, rhodium, and palladium, and wherein the alloys of the foregoing metals is selected from the group consisting of an alloy of platinum, an alloy of rhodium, an alloy of palladium, an alloy of rhenium, an alloy of tungsten, an alloy of gold, an alloy of silver, and an alloy of tantalum.

15. An embolic device, comprising:
an elongate flat member having a longitudinal axis, a first side comprising a first side surface, and a second side comprising a second side surface, the first and second sides being reverse to each other with the first side surface and second side surface facing in opposite directions, the elongate flat member composed of a metal selected from the group consisting of: a Platinum Group metal, rhenium, tungsten, gold, silver and tantalum, and an alloy of any of the foregoing metals,
the elongate flat member having an elongated constrained configuration for being deployed through a delivery catheter to targeted vascular site, and a three-dimensional unconstrained configuration,
wherein in the three-dimensional unconstrained configuration, the elongate flat member assumes a plurality of successive loops in which the elongate flat member is at least partially twisted about the longitudinal axis of the elongate flat member between each loop of the plurality, so that the first side surface faces externally of each loop, and the second side surface faces an interior of each loop, respectively, regardless of a change in direction and/or orientation of the elongate flat member, wherein loops that are directly adjacent loops to a first loop of the plurality have respective winding axes which are non-collinear and angled to a winding axis of the first loop, and wherein the first loop is formed by winding the elongate flat member in a first direction and the adjacent loops are formed by winding the elongate flat member in an opposite direction to the first direction when viewed down an axis towards the centroid of the three-dimensional unconstrained configuration.

Assignees

• Stryker Corp
• Stryker European Operations Ltd

Inventors

• Porter Stephen
• Lee Andrew S

Classifications

• A61B17/12145 Primary

  having a pre-set deployed three-dimensional shape (methods of manufacturing A61B2017/00526) · CPC title

• A61B17/1214

  Coils or wires · CPC title

• A61B17/12031 Primary

  complete occlusion · CPC title

• A61B17/12113

  within an aneurysm · CPC title

• A61B17/12172 Primary

  having a pre-set deployed three-dimensional shape (methods of manufacturing A61B2017/00526) · CPC title