Method and device for transferring liquids
US-2017176303-A1 · Jun 22, 2017 · US
US11814196B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11814196-B2 |
| Application number | US-201916718547-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 18, 2019 |
| Priority date | Dec 21, 2018 |
| Publication date | Nov 14, 2023 |
| Grant date | Nov 14, 2023 |
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A pressure-tight storage vessel contains a liquid, has an elongated main body rotationally symmetrical with respect to an axis of symmetry, and forms, at least partially, a rotationally symmetrical hollow space in which the liquid is substantially received, wherein the main body is terminated at its bottom side by a base. Furthermore, at its top side, the storage vessel has an opening which is closed off in a pressure-tight manner by a closure, has a plurality of reinforcement elements, which bears against the main body at the outside, which extends parallel to the axis of symmetry of the main body, and arranged rotationally symmetrically about the axis of symmetry of the main body. In each case between adjacent reinforcement elements, respective externally exposed wall sections of the main body are formed, and the composition of the exposed wall sections permits a pressure-tight insertion by at least two hollow needles.
Opening claim text (preview).
The invention claimed is: 1. A pressure-tight storage vessel containing a liquid, comprising: an elongated main body which is rotationally symmetrical with respect to an axis of symmetry and which forms, at least sectionally, a rotationally symmetrical hollow space, in which a liquid is substantially received, wherein the elongated main body is terminated at a bottom side by a base, and has an opening at a top side which is closed off in a pressure-tight manner by a closure, and a plurality of reinforcement elements, which bears against the elongated main body at the outside, which extends parallel to said axis of symmetry, and which is arranged rotationally symmetrically about said axis of symmetry such that, in each case between adjacent reinforcement elements, respective externally exposed wall sections of the elongated main body are formed, wherein the composition of the externally exposed wall sections permits a pressure-tight insertion by at least two hollow needles, wherein the main body has no separating seam and no sprue residues on the externally exposed wall sections for the pressure-tight insertion by the at least two hollow needles, wherein the storage vessel has a border at the top side, wherein said border encircles the opening and which is spaced apart from an outer boundary of the opening, wherein the closure is an aluminum or plastic film attached to the border by melting, wherein the main body and the reinforcement elements comprises plastic and are produced in one piece from the plastic by an injection moulding process, wherein the main body has a recess at a bottom side of the elongated main body, and wherein the base is curved from the lowest point of the base extending to the inner wall of the main body, wherein the reinforcement elements and the elongated main body extend as far as the bottom side of the storage vessel, wherein the reinforcement elements form, together with the main body, guide grooves, which are open towards the bottom side of the elongated main body, and wherein the storage vessel has a shoulder at the top side, wherein the shoulder delimits the guide grooves towards the top side. 2. The storage vessel according to claim 1 , wherein the respective externally exposed wall sections have a respectively equal wall thickness. 3. The storage vessel according to claim 1 , wherein said plastic is polyethylene. 4. The storage vessel according to claim 1 , wherein an inner side of the main body has a substantially constant surface roughness. 5. The storage vessel according to claim 1 , wherein the wall thickness of the exposed wall sections is greater than 0.15 mm. 6. The storage vessel according to claim 1 , wherein the liquid constitutes an inhomogeneous liquid phase. 7. The storage vessel according to claim 1 , wherein the liquid constitutes a homogeneous liquid phase. 8. The storage vessel according to claim 1 , wherein the elongated main body forms, at least sectionally or at least partially, a circular-cylindrical hollow space or a conical-cylindrical hollow space. 9. The storage vessel according to claim 4 , wherein the substantially constant surface roughness has an average roughness depth of less than 0.8 Rz. 10. The storage vessel according to claim 5 , wherein the wall thickness of the exposed wall sections is greater than 0.2 min. 11. The storage vessel according to claim 6 , wherein the liquid comprises an aqueous solution comprising beads. 12. The storage vessel according to claim 7 , wherein the liquid is at least one selected from the group consisting of a biological agent in an aqueous solution, a chemical agent in an aqueous solution, a liquid sample, a blood sample, and a serum. 13. The storage vessel according to claim 1 , wherein the film of the closure comprises an aluminum or plastic film, having a thickness of 5 micrometers to 5 mm. 14. The storage vessel according to claim 13 , wherein the film is a multi-layered film comprising an aluminum layer and a plastic layer. 15. A magazine for storing multiple storage vessels, comprising: at least one of the storage vessel according to claim 1 , and at least one magazine channel, which extends from a top side of the magazine as far as a bottom side of the magazine and into which the at least one storage vessel can be pushed, with the bottom side of the storage vessel first, from the top or the top side of the magazine, wherein, in a lower region of the at least one magazine channel, a mechanically flexible retaining element is located, which, in a rest position, projects into the at least one magazine channel, which is formed such that, in a first position of the storage vessel, the mechanically flexible retaining element engages into one of the guide grooves and also the shoulder of the storage vessel comes to bear against the mechanically flexible retaining element. 16. The magazine for storing multiple storage vessels according to claim 15 , wherein, in the lower region of the magazine channel, at least in a second position of the storage vessel below the first position, the mechanically flexible guide element engages into one of the guide grooves and bears against the reinforcement elements forming the guide groove, wherein, in the second position, the storage vessel projects with its bottom side from the magazine channel. 17. A method for transferring a liquid from a storage vessel into a reaction vessel, comprising: a) inserting, in a pressure-tight manner, a first hollow needle into the storage vessel according to claim 1 , wherein said first hollow needle is connected to a flushing liquid reservoir, b) inserting, in a pressure-tight manner, a second hollow needle into the storage vessel, wherein said second hollow needle is connected to the reaction vessel, and c) introducing a flushing liquid via the first hollow needle from the flushing liquid reservoir into the storage vessel, with expulsion of the liquid via the second hollow needle from the storage vessel into the reaction vessel.
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