Automatic patient recruitment system and methods for use therewith

Patent metadata

Field	Value
Publication number	US-11810037-B2
Application number	US-202117447950-A
Country	US
Kind code	B2
Filing date	Sep 17, 2021
Priority date	Nov 21, 2018
Publication date	Nov 7, 2023
Grant date	Nov 7, 2023

Abstract

An automatic patient recruitment system is operable generate abnormality data for medical scans by performing at least one inference function on image data of each medical scans by utilizing a computer vision model trained on a training set of medical scans. A subset of a plurality of patients is identified to be eligible for a pharmaceutical study by identifying medical scans having abnormality data that compares favorably to abnormality criteria of the pharmaceutical study. A size of the subset is compared to a minimum participant count requirement. A notification indicating the subset of the plurality of patients is transmitted based on the size of the subset comparing favorably to the minimum participant count requirement.

First claim

What is claimed is:

1. An automatic patient recruitment system, comprising:
at least one processor; and
a memory that stores operational instructions that, when executed by the at least one processor, cause the automatic patient recruitment system to:
generate abnormality data for each of a plurality of medical scans of a plurality of patients via artificial intelligence by performing at least one inference function on image data of the plurality of medical scans, wherein the at least one inference function utilizes a computer vision model trained on a training set of medical scans;
generate a plurality of subsets of the plurality of patients, wherein each subset of the plurality of patients corresponds to one of a plurality of pharmaceutical studies, wherein each subset of the plurality of patients is generated by identifying ones of the plurality of patients with corresponding ones of the plurality of medical scans having abnormality data that compares favorably to abnormality criteria of a set of eligibility criteria of the corresponding one of the plurality of pharmaceutical studies, and with corresponding patient data that compares favorably to other patient criteria of the set of eligibility criteria of the one of the plurality of pharmaceutical studies;
determine a first minimum participant count requirement for a first one of the plurality of pharmaceutical studies, wherein a first notification indicating a first one of the plurality of subsets of the plurality of patients corresponding to the first one of the plurality of pharmaceutical studies is transmitted in response to determining a size of the first one of the plurality of subsets of the plurality of patients compares favorably to the first minimum participant count requirement;
determine a second minimum participant count requirement for a second one of the plurality of pharmaceutical studies;
forego transmission of a notification indicating a second one of the plurality of subsets of the plurality of patients corresponding to the second one of the plurality of pharmaceutical studies in response to determining a size of the second one of the plurality of subsets of the plurality of patients that corresponds to the second one of the plurality of pharmaceutical studies compares unfavorably to the second minimum participant count requirement;
receive at least one new medical scan for at least one new patient after determining the size of the second one of the plurality of subsets of the plurality of patients compares unfavorably to the second minimum participant count requirement;
add the at least one new patient to the second one of the plurality of subsets of the plurality of patients in response to determining that the at least one new patient is eligible for the second one of the plurality of pharmaceutical studies by determining the at least one new medical scan has abnormality data that compares favorably to the abnormality criteria of the second one of the plurality of pharmaceutical studies and by determining that the at least one new patient has patient data that compares favorably to the other patient criteria of the second one of the plurality of pharmaceutical studies;
determine a new size of the second one of the plurality of subsets of the plurality of patients compares favorably to the second minimum participant count requirement in response to adding the at least one new patient; and
transmit a second notification indicating the second one of the plurality of subsets of the plurality of patients, wherein the second notification is transmitted in response to determining the new size of the second one of the plurality of subsets of the plurality of patients compares favorably to the second minimum participant count requirement.

2. The automatic patient recruitment system of claim 1 wherein the operational instructions, when executed by the at least one processor, further cause the automatic patient recruitment system to:
identify a first one of the plurality of patients that is eligible for the first one of the plurality of pharmaceutical studies by determining a first one of the plurality of medical scans of the first one of the plurality of patients has abnormality data that compares favorably to the abnormality criteria of the first one of the plurality of pharmaceutical studies and by determining that the first one of the plurality of patients has patient data that compares favorably to the other patient criteria of the first one of the plurality of pharmaceutical studies;
generate a first notification indicating the first one of the plurality of patients is eligible for the first one of the plurality of pharmaceutical studies for transmission to a first client device for display via a display device;
identify a second one of the plurality of patients that is eligible for a second one of the plurality of pharmaceutical studies by determining a second one of the plurality of medical scans of the second one of the plurality of patients has abnormality data that compares favorably to the abnormality criteria of the second one of the plurality of pharmaceutical studies and by determining that the second one of the plurality of patients has patient data that compares favorably to the other patient criteria of the second one of the plurality of pharmaceutical studies, wherein the second one of the plurality of patients is determined to not be eligible for the first one of the plurality of pharmaceutical studies; and
generate a second notification indicating the second one of the plurality of patients is eligible for the second one of the plurality of pharmaceutical studies for transmission.

3. The automatic patient recruitment system of claim 2 , wherein the first client device is associated with a first user that is associated with the first one of the plurality of pharmaceutical studies, wherein a second client device is associated with a second user that is associated with the second one of the plurality of pharmaceutical studies, and wherein the second notification is transmitted to the second client device for display via a second display device.

4. The automatic patient recruitment system of claim 3 , wherein the operational instructions, when executed by the at least one processor, further cause the automatic patient recruitment system to:
receive the set of eligibility criteria corresponding to the first one of the plurality of pharmaceutical studies from the first client device, wherein the set of eligibility criteria corresponding to the first one of the plurality of pharmaceutical studies is generated by the first client device based on user input to the first client device in response to a first prompt displayed via a first user interface on a first display device associated with the first client device; and
receive the set of eligibility criteria corresponding to the second one of the plurality of pharmaceutical studies from the second client device, wherein the set of eligibility criteria corresponding to the second one of the plurality of pharmaceutical studies is generated by the second client device based on user input to the second client device in response to a second prompt displayed via a second user interface on the second display device.

5. The automatic patient recruitment system of claim 2 , wherein the first client device is associated with a user that is an administrator of the automatic patient recruitment system, wherein the second notification is transmitted to the first client device, wherein the first client device generates a third notification, indicating the first one of the plurality of patients, for transmission to a second client device, associated with a second user that is associated with the first one of the plurality of pharmaceutical studies, and wherein the first client device generates a fourth n

Assignees

• Enlitic Inc

Inventors

• Lyman Kevin
• Upton Anthony
• Yao Li
• Covington Ben
• Lui Keith

Classifications

• G06T12/20

  Inverse problem, i.e. transformations from projection space into object space · CPC title

• G06T11/26

  Drawing of charts or graphs · CPC title

• G06T11/10

  Texturing; Colouring; Generation of textures or colours (retouching, inpainting or scratch removal G06T5/77) · CPC title

• G06N3/045

  Combinations of networks · CPC title

• G06N3/09

  Supervised learning · CPC title