3D calibration body, calibration method for the spatial calibration of an optical imaging system, calibration element and calibration method for calibrating an optical imaging system

Patent metadata

Field	Value
Publication number	US-11803045-B2
Application number	US-201916458039-A
Country	US
Kind code	B2
Filing date	Jun 29, 2019
Priority date	Jun 29, 2018
Publication date	Oct 31, 2023
Grant date	Oct 31, 2023

Abstract

A 3D calibration body for spatial calibration of an optical imaging system includes a transparent body and calibration marks embedded in a volume of the transparent body. At least some of the calibration marks are selectively activatable and deactivatable, wherein an activated calibration mark is visible in the visible spectral range and a deactivated calibration mark is not visible in the visible spectral range.

First claim

What is claimed is:

1. A 3-dimensional (3D) calibration body for a spatial calibration of an optical imaging system, the 3D calibration body comprising:
a transparent body having a volume; and
calibration marks embedded in the volume of the transparent body, at least some of the calibration marks being selectively activatable and deactivatable by a controller, and
an activated calibration mark being visible in a visible spectral range and a deactivated calibration mark not being visible in the visible spectral range,
wherein the transparent body is made of a stack of layers,
wherein the calibration marks are arranged in individual layers of the stack of layers,
wherein the individual layers form areal light guides with interfaces,
wherein each of the areal light guides is configured such that evanescent fields of light guided in the light guides occur at the interfaces of the light guides,
wherein the calibration marks are formed by structures at the interfaces of the light guides at which the evanescent fields are output coupled from the respective light guides as propagating electromagnetic waves,
wherein an input coupling apparatus input couples the light into the areal light guides, and
wherein the input coupling apparatus renders it possible to activate and deactivate input coupling of the light into individual ones of the areal light guides.

2. The 3D calibration body according to claim 1 , wherein the calibration marks are selectively activatable and deactivatable in different planes of the transparent body.

3. The 3D calibration body according to claim 1 , wherein the calibration marks are combined to form at least two groups of calibration marks and at least one of the groups of calibration marks is activatable and deactivatable.

4. The 3D calibration body according to claim 3 , wherein the calibration marks of a group of the at least two groups of calibration marks are arranged within a plane in the transparent body.

5. The 3D calibration body according to claim 1 , wherein:
at least one of the individual layers of the stack of layers is formed by a transparent display, and
the selectively activatable and deactivatable calibration marks are structures displayed on the transparent display.

6. The 3D calibration body according to claim 5 , further comprising:
a background illumination arrangement for the at least one of the individual layers formed by the transparent display.

7. The 3D calibration body according to claim 1 , wherein:
total-internal reflection of the light input coupled into the areal light guides occurs at the interfaces of the areal light guides, and
the calibration marks are formed by local structures at the interfaces of the areal light guides, at which a conversion takes place from the evanescent fields into electromagnetic waves capable of propagation.

8. The 3D calibration body according to claim 1 , further comprising an arrangement of the calibration marks, wherein:
the arrangement of the calibration marks has a distribution of the calibration marks in the transparent body, a spatial frequency of which changes within the transparent body, or
the arrangement of calibration marks has a self-similar distribution of the calibration marks in the transparent body.

9. The 3D calibration body according to claim 8 , wherein:
the distribution of the calibration marks in the transparent body is formed by patterns of the calibration marks arranged in the layers of a stack of layers,
each of the patterns of the calibration marks has a distribution of the calibration marks within a respective layer, the spatial frequency of which changes within the layer, or
the patterns have a self-similar distribution of the calibration marks.

10. The 3D calibration body according to claim 8 , wherein the spatial frequency is reduced from a center of the transparent body towards an edge of the transparent body.

11. The 3D calibration body according to claim 8 , wherein an extent of respective calibration marks changes with the spatial frequency.

12. The 3D calibration body according to claim 11 , wherein the extent of the respective calibration marks increases from a center of the transparent body towards an edge of the transparent body.

13. A method for spatial calibration of an optical imaging system, the method comprising:
recording an arrangement of calibration marks at different distances and/or different tilt angles of the optical imaging system relative to an arrangement of the calibration marks to obtain a spatial information item,
carrying out the spatial calibration based on the spatial information item obtained with the 3D calibration body according to claim 1 , and
forming the arrangement of the calibration marks with the calibration marks of the 3D calibration body.

Assignees

• Zeiss Carl Meditec Ag

Inventors

• Omlor Lars
• Glasenapp Carsten

Classifications

• G02B21/025 Primary

  with variable magnification (variable magnification G02B15/00) · CPC title

• A61B5/0077

  Devices for viewing the surface of the body, e.g. camera, magnifying lens · CPC title

• A61B90/39

  Markers, e.g. radio-opaque or breast lesions markers · CPC title

• G02B21/0012

  Surgical microscopes (counterbalanced structures for surgical microscopes G02B7/001) · CPC title

• G02B21/22

  Stereoscopic arrangements · CPC title