Production method for pre-filled syringe and pre-filled syringe production device
US-2015190578-A1 · Jul 9, 2015 · US
US11801956B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11801956-B2 |
| Application number | US-202017595138-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 22, 2020 |
| Priority date | May 23, 2019 |
| Publication date | Oct 31, 2023 |
| Grant date | Oct 31, 2023 |
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A filling unit to fill a container, in particular a cartridge, with a liquid product of the pharmaceutical industry having: a dosing head, which is arranged in a filling station and is designed to feed a quantity of product into the container through an open upper end of the container; a capping device, which is arranged in a capping station and is designed to insert a closing element into the container and through the open upper end of the container; and a sucking device which is arranged in a degasification station located between the filling station and the capping station, is designed to engage the open upper end of the container in a sealing manner, and is designed to generate a depression inside the container in an upper volume, which is not occupied by the product.
Opening claim text (preview).
The invention claimed is: 1. A filling unit ( 11 ) to fill a container ( 1 ) with a liquid product ( 5 ) of the pharmaceutical industry; the filling unit ( 11 ) comprising: a dosing head ( 12 ), which is arranged in a filling station (S 1 ) and is designed to feed a quantity of product ( 5 ) into the container ( 1 ) through an open upper end of the container ( 1 ); a capping device ( 18 ), which is arranged in a capping station (S 3 ) and is designed to insert a closing element into the container ( 1 ) and through the open upper end of the container ( 1 ); and a first sucking device ( 15 ), which is arranged in a degasification station (S 2 ) located between the filling station (S 1 ) and the capping station (S 3 ), is designed to engage the open upper end of the container ( 1 ) in a sealing manner, and is designed to generate a depression inside the container ( 1 ) in an upper volume, which is not occupied by the product ( 5 ), wherein: the first sucking device ( 15 ) is designed to generate the depression inside the container ( 1 ) in the upper volume, which is not occupied by the product ( 5 ), by sucking only and exclusively air and without sucking any part of the product or any foam that is generated during feeding of the product. 2. The filling unit ( 11 ) according to claim 1 , wherein the first sucking device ( 15 ) is designed to generate a depression sufficient to suck part of the air but completely insufficient to suck any part of the product ( 5 ) or any foam that is generated during the feeding of the product ( 5 ). 3. The filling unit ( 11 ) according to claim 1 , wherein the first sucking device ( 15 ) is designed to generate a depression inside the container ( 1 ) ranging from 1,000 to 10,000 Pascal and is designed to maintain the depression for an amount of time ranging from 0.4 to 3 seconds. 4. The filling unit ( 11 ) according to claim 1 , wherein the first sucking device ( 15 ) comprises a first elastic cap ( 16 ), which is designed to engage the open upper end of the container ( 1 ). 5. The filling unit ( 11 ) according to claim 1 and comprising a second sucking device ( 20 ), which is arranged in the capping station (S 3 ), is designed to engage the open upper end of the container ( 1 ) in a sealing manner, and is designed to generate a depression inside the container ( 1 ) in an upper volume, which is not occupied by the product ( 5 ), during the insertion of the closing element. 6. The filling unit ( 11 ) according to claim 5 , wherein the second sucking device ( 20 ) is designed to generate a depression inside the container ( 1 ) in the upper volume, which is not occupied by the product ( 5 ), by sucking only and exclusively air. 7. The filling unit ( 11 ) according to claim 6 , wherein the second sucking device ( 20 ) is designed to generate a depression inside the container ( 1 ) in the upper volume, which is not occupied by the product ( 5 ), by sucking only and exclusively air and therefore without sucking any part of the product ( 5 ) or any foam that is generated during the feeding of the product ( 5 ). 8. The filling unit ( 11 ) according to claim 5 , wherein the second sucking device ( 20 ) is designed to generate a depression sufficient to suck part of the air but completely insufficient to suck any part of the product ( 5 ) or any foam that is generated during the feeding of the product ( 5 ). 9. The filling unit ( 11 ) according to claim 5 , wherein the second sucking device ( 20 ) comprises a chamber ( 21 ), inside which the depression is generated and along which the closing element is caused to pass. 10. The filling unit ( 11 ) according to claim 5 , wherein the second sucking device ( 20 ) is designed to generate a depression inside the container ( 1 ) ranging from 1,000 to 10,000 Pascal and is designed to maintain the depression for an amount of time ranging from 0.2 to 2 seconds. 11. The filling unit ( 11 ) according to claim 5 , wherein the second sucking device ( 20 ) comprises a second elastic cap ( 22 ) which is designed to engage the open upper end of the container ( 1 ). 12. The filling unit ( 11 ) according to claim 5 , wherein between the degasification station (S 2 ) and the capping station (S 3 ) there is a rest station (S 4 ), in which the end of the container ( 1 ) is free and in communication with the external environment.
the nozzles acting from above on containers or wrappers open at their top (B65B31/044 take precedence) · CPC title
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mechanically, e.g. by pistons or pumps · CPC title
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