Nasogastric device and method

Patent metadata

Field	Value
Publication number	US-11801204-B2
Application number	US-201916979275-A
Country	US
Kind code	B2
Filing date	Mar 11, 2019
Priority date	Mar 9, 2018
Publication date	Oct 31, 2023
Grant date	Oct 31, 2023

Abstract

A nasogastric device and method is provided, including a first flexible tube configured to be threaded through the nose of a patient, down the esophagus and into the stomach for enteral feeding, a second flexible tube disposed adjacent to the first tube having a distal end, the distal end of said second tube configured to terminate inside the esophagus for delivery of liquids to the esophagus or for sampling of the local environment, an inflatable balloon configured around said first and second flexible tubes, a third flexible tube configured to inflate said inflatable balloon; and a fourth flexible tube communicating with an exterior portion of said inflatable balloon, the fourth tube configured to transport suspensions or solutions of materials; and an elastomeric sleeve which is used to control delivery of therapeutic suspensions of solutions of materials to the exterior of the device to the adjacent esophageal tissue.

First claim

The invention claimed is:

1. A nasogastric device, comprising: a first flexible tube having a distal end configured to be threaded through a nose of a patient, down an esophagus and into a stomach; a second flexible tube disposed adjacent to the first tube having a distal end proximate to the distal end of said first flexible tube, the distal end of said second tube configured to terminate inside the esophagus; an inflatable balloon configured around said first and second flexible tubes, the inflatable balloon disposed proximal to the distal end of the first and second flexible tubes; a third flexible tube in fluid communication with said inflatable balloon configured to inflate said inflatable balloon; and a fourth flexible tube having a distal end portion communicating with an exterior portion of said inflatable balloon, the fourth tube configured to transport suspensions or solutions of materials, such as therapeutic molecules into a space exterior to said inflatable balloon and an elastomeric sleeve at least partially surrounding said inflatable balloon, the elastomeric sleeve in fluid communication with said fourth tube, the elastomeric sleeve including perforations configured to allow release of said therapeutic molecules there through.

2. A nasogastric device in accordance with claim 1 , wherein at least a last 5 centimeters of the distal end of said first flexible tube includes perforations.

3. A nasogastric device in accordance with claim 1 , wherein said inflatable balloon has an initial radius of between about 5 millimeters and 2 centimeters.

4. A nasogastric device in accordance with claim 1 , wherein said inflatable balloon has an initial length of between about 0.5 and 30 centimeters.

5. A nasogastric device in accordance with claim 1 , wherein the elastomeric sleeve is configured to closely surround at least a portion of the inflatable balloon such that inflation of the inflatable balloon pushes the therapeutic molecules contained within the elastomeric sleeve through the perforations of elastomeric sleeve.

6. A nasogastric device in accordance with claim 1 , further comprising at least one radiopaque marker provided near a distal portion of an element of said nasogastric device.

7. A nasogastric device in accordance with claim 1 , further comprising ports configured at the proximal ends of each of said first, second third and fourth flexible tubes.

8. A nasogastric device in accordance with claim 1 , wherein the distal end of said second flexible tube extends between 1 and 10 centimeters below the distal end of said inflatable balloon.

9. A nasogastric device in accordance with claim 8 , wherein at least a portion of said distal end of the second flexible tube includes perforations that have a length of between 1 and 3 millimeters.

10. A nasogastric device in accordance with claim 1 , wherein at least a portion of the distal end of said first flexible tube includes perforations configured to allow said therapeutic molecules to exit freely into the stomach.

11. A nasogastric device in accordance with claim 10 , wherein said perforations of the distal end of said first flexible tube have a length between 1 and 8 millimeters.

12. A nasogastric device in accordance with claim 10 , wherein said perforations of the elastomeric sleeve are configured as semicircular patterns.

13. A nasogastric device in accordance with claim 12 , wherein said perforations of the elastomeric sleeve have lengths between about 0.5 micrometers and 25 millimeters.

14. A method of treating an esophageal stricture, comprising: providing a nasogastric device, including: a first flexible tube having a distal end configured to be threaded through a nose of a patient, down an esophagus and into a stomach; a second flexible tube disposed adjacent to the first tube having a distal end proximate to the distal end of said first flexible tube, the distal end of said second tube configured to terminate inside the esophagus; an inflatable balloon configured around said first and second flexible tubes, the inflatable balloon disposed proximal to the distal end of the first and second flexible tubes; a third flexible tube in fluid communication with said inflatable balloon configured to inflate said inflatable balloon; and a fourth flexible tube having a distal end portion communicating with an exterior portion of said inflatable balloon, the fourth tube configured to transport suspensions or solutions of materials, such as therapeutic molecules into a space exterior to first inflatable balloon; and positioning said nasogastric device utilizing visualized radiopaque markers at an esophageal stricture; injecting said therapeutic molecules through said fourth flexible tube; and inflating the inflatable balloon against said esophageal stricture and simultaneously delivering said therapeutic molecules to esophageal tissue adjacent the inflatable balloon; wherein an elastomeric sleeve at least partially surrounds said inflatable balloon, and wherein said inflating of said inflatable balloon forces said therapeutic molecules through perforations of elastomeric sleeve to esophageal tissue adjacent to the device.

15. A method in accordance with claim 14 , wherein the distal end of said second flexible tube extends between 1 and 10 centimeters below the distal end of said inflatable balloon.

16. A method in accordance with claim 15 , wherein at least a portion of said distal end of the second flexible tube includes perforations that have a length of between 1 and 3 millimeters.

17. A method in accordance with claim 14 , further comprising additionally providing enteral feeding via said first flexible tube.

18. A method in accordance with claim 17 , wherein said first flexible tube includes perforations on at least a distal portion thereof to facilitate said enteral feeding.

19. A method in accordance with claim 17 , wherein said perforations have a length of between 1 and 8 millimeters.

Assignees

• Univ Connecticut
• Connecticut Childrens Medical Center

Inventors

• Finck Christine
• Kuhn Liisa
• Burke Kelly A
• Jensen Todd

Classifications

• A61J15/0003 Primary

  Nasal or oral feeding-tubes, e.g. tube entering body through nose or mouth · CPC title

• A61J15/0049

  Inflatable Balloons (balloon catheters A61M25/10) · CPC title

• A61M2025/1061

  having separate inflations tubes, e.g. coaxial tubes or tubes otherwise arranged apart from the catheter tube · CPC title