Delivery system having an integral centering mechanism for positioning a valve prosthesis in situ

Patent metadata

Field	Value
Publication number	US-11801136-B2
Application number	US-202217675033-A
Country	US
Kind code	B2
Filing date	Feb 18, 2022
Priority date	Jan 27, 2015
Publication date	Oct 31, 2023
Grant date	Oct 31, 2023

Abstract

Embodiments hereof relate to a delivery system for a transcatheter valve prosthesis, the delivery system having an integral centering mechanism to circumferentially center both the delivery system and the valve prosthesis within a vessel at the target implantation site. The centering mechanism may include expandable wings that may be selectively aligned with openings formed through a sidewall of an outer shaft of the delivery system, a coiled wing that may be selectively exposed through an opening formed through a sidewall of an outer shaft of the delivery system, a plurality of elongated filaments extending through a plurality of lumens of an outermost shaft of the delivery system that may be selectively deployed or expanded, an outer shaft that includes at least one pre-formed deflection segment formed thereon, a tool having a deployable lever arm, and/or a plurality of loops deployable via simultaneous longitudinal and rotational movement.

First claim

What is claimed is:

1. A delivery system for a valve prosthesis configured for delivery within a vasculature, the delivery system comprising:
an outermost shaft defining a central lumen and defining a plurality of lumens in a sidewall thereof;
an outer shaft disposed within the central lumen of the outermost shaft, the outer shaft defining a lumen and being movable with respect to the outermost shaft;
an inner shaft disposed within the lumen of the outer shaft, the inner shaft having a distal portion being configured to receive the valve prosthesis thereon; and
a centering mechanism integrated onto the outermost shaft, the centering mechanism having a delivery configuration and an expanded configuration configured to circumferentially center the delivery system and the valve prosthesis within a native valve annulus in situ, wherein the centering mechanism has a straightened profile when in the delivery configuration and the centering mechanism has a curved, bowed profile radially larger than the outermost shaft and distal to a distal end of the outermost shaft when in the expanded configuration, and wherein the centering mechanism includes a plurality of elongated filaments each slidingly positioned within the plurality of lumens of the outermost shaft.

2. The delivery system of claim 1 , wherein the outermost shaft is shorter than the outer shaft and the distal end of the outermost shaft is positioned proximal to a distal end of the outer shaft when the centering mechanism is in the expanded configuration.

3. The delivery system of claim 1 , wherein
each elongated filament having at least a distal portion formed from a self-expanding material, wherein when each elongated filament is in the delivery configuration the distal portion of each elongated filament is enclosed within one of the lumens in the sidewall of the outermost shaft and when each elongated filament is in the expanded configuration the distal portion of each elongated filament extends out of the distal end of the outermost shaft.

4. The delivery system of claim 1 , wherein
a distal end of each elongated filament being attached to an outer surface of the outer shaft, wherein when each elongated filament is in the delivery configuration a distal portion of each elongated filament is flush against the outer surface of the outer shaft and when each elongated filament is in the expanded configuration the distal portion of each elongated filament has the curved, bowed profile.

5. The delivery system of claim 1 , wherein the outer shaft is rotatable and slidable relative to the outermost shaft.

6. A delivery system for a valve prosthesis configured for delivery within a vasculature, the delivery system comprising:
an outermost shaft defining a central lumen and defining a plurality of lumens in a sidewall thereof;
an outer shaft disposed within the central lumen of the outermost shaft, the outer shaft defining a lumen and being movable with respect to the outermost shaft;
an inner shaft disposed within the lumen of the outer shaft, the inner shaft having a distal portion being configured to receive the valve prosthesis thereon; and
a centering mechanism integrated onto the outermost shaft, the centering mechanism having a delivery configuration and an expanded configuration configured to circumferentially center the delivery system and the valve prosthesis within a native valve annulus in situ, wherein the centering mechanism includes a plurality of elongated filaments slidingly positioned within the plurality of lumens of the outermost shaft, and wherein a distal portion of each elongated filament is enclosed within one of the lumens in the sidewall of the outermost shaft when the centering mechanism is in the delivery configuration and the distal portion of each elongated filament extends out of a distal end of the outermost shaft when the centering mechanism is in the expanded configuration.

7. The delivery system of claim 6 , wherein the distal end of the outermost shaft is flared.

8. The delivery system of claim 6 , wherein each elongated filament is individually deployable.

9. The delivery system of claim 6 , wherein the distal portion of each elongated filament is more flexible than a proximal portion thereof.

10. The delivery system of claim 6 , wherein the distal portion of each elongated filament has a curved, bowed profile radially larger than the outermost shaft and distal to the distal end of the outermost shaft when in the expanded configuration.

11. The delivery system of claim 10 , wherein at least the distal portion of each elongated filament is formed from a self-expanding material.

12. The delivery system of claim 6 , wherein the distal portion of each elongated filament curls radially outward and longitudinally in a proximal direction such that a distal end of each elongated filament contacts an outer surface of the outermost shaft when in the expanded configuration.

13. The delivery system of claim 6 , wherein the outermost shaft is shorter than the outer shaft and the distal end of the outermost shaft is positioned proximal to a distal end of the outer shaft when the centering mechanism is in the expanded configuration.

14. The delivery system of claim 6 , wherein the plurality of elongated filaments includes exactly eight filaments.

15. A delivery system for a valve prosthesis configured for delivery within a vasculature, the delivery system comprising:
an outer shaft defining a plurality of lumens in a sidewall thereof;
an inner shaft disposed within the outer shaft, the inner shaft having a distal portion being configured to receive the valve prosthesis thereon; and
a centering mechanism integrated onto the delivery system, the centering mechanism having a delivery configuration and an expanded configuration configured to circumferentially center the delivery system and the valve prosthesis within a native valve annulus in situ, wherein the centering mechanism has a straightened profile and is disposed within the outer shaft when in the delivery configuration and the centering mechanism has a curved, bowed profile radially spaced apart from an outer surface of the outer shaft when in the expanded configuration, and wherein the centering mechanism includes a plurality of elongated filaments each slidingly positioned within the plurality of lumens of the outer shaft.

Assignees

• Medtronic Vascular Inc

Inventors

• Barrett Donna
• Cunningham Kieran
• Harewood Frank

Classifications

• A61F2/2436 Primary

  Deployment by retracting a sheath · CPC title