Methods and systems for determining the presence of a molecule in a sample and method and system for determining a range-resolved concentration of a molecule in a scene
US-11119044-B2 · Sep 14, 2021 · US
US11796475B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11796475-B2 |
| Application number | US-201917286304-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 15, 2019 |
| Priority date | Oct 16, 2018 |
| Publication date | Oct 24, 2023 |
| Grant date | Oct 24, 2023 |
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There is described a method for performing a Raman spectroscopy measurement on a sample. The method generally has sequentially illuminating an area of said sample with first and second excitation signals, said first excitation signal being slightly spectrally spaced-apart from said second excitation signal, resulting in said area sequentially emitting first and second emission signals; upon receiving said first emission signal, measuring a first intensity value being indicative of optical intensity of said first emission signal within at least a detection band; upon receiving said second emission signal, measuring a second intensity value being indicative of optical intensity of said second emission signal within said detection band; and performing said Raman spectroscopy measurement by comparing said first intensity value to said second intensity value.
Opening claim text (preview).
What is claimed is: 1. A method for performing a Raman spectroscopy measurement on a sample, said method comprising: sequentially illuminating an area of said sample with first and second excitation signals, said first excitation signal being slightly spectrally spaced-apart from said second excitation signal, resulting in said area sequentially emitting first and second emission signals; upon receiving said first emission signal, measuring a first intensity value being indicative of optical intensity of said first emission signal within at least a detection band; upon receiving said second emission signal, measuring a second intensity value being indicative of optical intensity of said second emission signal within said detection band; and performing said Raman spectroscopy measurement by comparing said first intensity value to said second intensity value; wherein said sequentially illuminating comprises sequentially illuminating an area of said sample with first, second and third excitation signals, said first, second and third excitation signals being slightly spectrally spaced-apart from one another, resulting in said area sequentially emitting first, second and third emission signals, the method further comprising measuring a third intensity value indicative of optical intensity of said third emission signal within said detection band, said comparing said first intensity value to said second intensity value comprising estimating a fourth intensity value at said detection band based on said first and second intensity values, said performing comprising comparing said fourth intensity value to said third intensity value.
Raman scattering · CPC title
by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy (A61B5/0071 takes precedence) · CPC title
Fibre array at detector, resolving · CPC title
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