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Geranium oil and constituents thereof for treatment of neurodegenerative diseases
US11793767B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11793767-B2 |
| Application number | US-202016795709-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 20, 2020 |
| Priority date | May 7, 2012 |
| Publication date | Oct 24, 2023 |
| Grant date | Oct 24, 2023 |
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- Title
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Abstract
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The invention relates to the use of effective amount of Pelargonium graveolens essential oil or extract or constituents thereof selected from a group consisting of: (S)(−)citronellol, linalool, menthone and isomenthone or any combination thereof, in the preparation of a medicament for treating a mammal suffering from or susceptible to a neurodegenerative condition which can be improved or prevented by inhibition of acetylcholinesterase (ACliE).
First claim
Opening claim text (preview).
What is claimed is: 1. A method for treating a neurodegenerative condition, comprising administering to a subject in need thereof a composition comprising, as the sole active ingredient, geranium oil extracted from Pelargonium graveolens in an amount effective for the treatment of the neurodegenerative condition, wherein said neurodegenerative condition is selected from the group consisting of Alzheimer's disease, Parkinson's disease, Parkinsonian dementia (PDem), Parkinson's disease dementia (PDD), dementia with Lewy bodies (DLB), anorexia nervosa, traumatic brain injury (TBI), and Parkinson's disease falling short of dementia (CIND-PD). 2. The method of claim 1 , wherein said neurodegenerative condition is characterized by death of dopaminergic neurons. 3. The method of claim 1 , wherein said treating a neurodegenerative condition is by affecting the levels of acetylcholine. 4. The method of claim 3 , wherein said composition affects the levels of acetylcholine by inhibiting the enzymatic activity of acetylcholinesterase (AchE). 5. The method of claim 1 , wherein said composition is prepared from a stock solution having a concentration of 1000 mg geranium oil per ml.
Assignees
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Classifications
Magnoliopsida (dicotyledons) · CPC title
- A61K31/045Primary
Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates · CPC title
- A23L27/12Primary
from fruit, e.g. essential oils · CPC title
Plant extracts, their artificial duplicates or their derivatives · CPC title
Fatty acids or derivatives thereof; Fats or oils · CPC title
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- What does patent US11793767B2 cover?
- The invention relates to the use of effective amount of Pelargonium graveolens essential oil or extract or constituents thereof selected from a group consisting of: (S)(−)citronellol, linalool, menthone and isomenthone or any combination thereof, in the preparation of a medicament for treating a mammal suffering from or susceptible to a neurodegenerative condition which can be improved or preve…
- Who is the assignee on this patent?
- The State Of Israel Ministry Of Agriculture & Rural Development Agricultural Res Organization, The State Of Israel Ministry Of Agriculture & Rural Development Agriculture Res Organization
- What technology area does this patent fall under?
- Primary CPC classification A61K31/045. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Oct 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).