Inert apparatus for microfluidic motion using magnetic shape memory material

Patent metadata

Field	Value
Publication number	US-11786897-B2
Application number	US-202217677697-A
Country	US
Kind code	B2
Filing date	Feb 22, 2022
Priority date	Feb 22, 2021
Publication date	Oct 17, 2023
Grant date	Oct 17, 2023

Abstract

A magnetic shape memory (MSM) microfluidic device may include a flexible membrane positioned between a channel and an MSM element. The MSM element may engage the flexible membrane to deform the channel at portions of the flexible membrane that are adjacent to non-contracted portions of the MSM element. The flexible membrane may prevent contact between a fluid within the channel and the MSM element. Magnetic field components may be applied to the MSM element and moved along the MSM element enable fluidic flow within the channel while. The device may include an upper portion including the flexible membrane and a lower portion including the MSM element. The upper portion may be interchangeable with additional upper portions.

First claim

What is claimed is:

1. A magnetic shape memory (MSM) microfluidic device comprising:
an MSM element having a dimension, and configured to contract across the dimension at a first portion of the MSM element that is exposed to a first component of a magnetic field, the first component substantially parallel to the dimension, and simultaneously not contract across the dimension at a second portion of the MSM element that is exposed to a second component of the magnetic field, the second component not substantially parallel to the dimension; and
a flexible membrane positioned between a channel and the MSM element, wherein the MSM element engages the flexible membrane to deform the channel at portions of the flexible membrane that are adjacent to the MSM element, and wherein the flexible membrane prevents contact between a fluid within the channel and the MSM element.

2. The device of claim 1 , wherein the MSM element engages the flexible membrane to enable a cavity to form at portions of the flexible membrane that are adjacent to contracted portions of the MSM element, and wherein movement of the first component and second component of the magnetic field along the MSM element results in movement of the cavity.

3. The device of claim 1 , wherein the flexible membrane includes an inert material such as polyvinylchloride (PVC), polyethersulfone (PES), polytetrafluoroethylene (PTFE), low-density-polyethylene (PE-LD), high-density-polyethylene (PE-HD), ultra-high-molecular-weight polyethylene (PE-UHMW), polyurethane (PU), polyetherimide (PEI), polycarbonate (PC), polysulfone (PS), polyetheretherketone (PEEK), polypropylene (PP), polytetrafluoroethylene (PTFE, Teflon), or any combination thereof.

4. The device of claim 1 , further comprising at least one port providing fluid access to the channel.

5. The device of claim 1 , wherein the flexible membrane is a portion of a wall of a flexible tube, wherein the channel is defined within the flexible tube, wherein the device further comprises a body, wherein the flexible tube is positioned between the body and the MSM element, and wherein the MSM element compresses the channel at the portions of the flexible membrane that are adjacent to the non-contracted portions of the MSM element by compressing the tube between the body and the MSM element at portions of the tube that are adjacent to the non-contracted portions of the MSM element, and wherein the MSM element opens the channel at portions of the tube that are adjacent to the contracted portions of the MSM element.

6. The device of claim 1 , further comprising:
an upper body, wherein the flexible membrane is a film fused to the upper body along a first portion of a surface of the upper body, and wherein the channel is defined along a second portion of the surface of the upper body to which the film is not fused; and
a lower body configured to attach to the upper body, wherein the MSM element is positioned between the upper body and the lower body, and wherein the MSM element compresses the channel at the portions of the film that are adjacent to the non-contracted portions of the MSM element by compressing the film between the upper body and the MSM element at portions of the film that are adjacent to the non-contracted portions of the MSM element, and wherein the MSM element opens the channel at portions of the film that are adjacent to the contracted portions of the MSM element.

7. The device of claim 6 , wherein the upper body is interchangeable with additional upper bodies having additional channels defined therein and having additional films, and wherein, when the additional upper bodies are attached to the lower body, the MSM element deforms the additional channels at portions of the additional films that are adjacent to the non-contracted portions of the MSM element by compressing the additional films between the additional upper bodies and the MSM element at portions of the additional films that are adjacent to the non-contracted portions of the MSM element, and wherein the MSM element opens the channel at portions of the additional films that are adjacent to the contracted portions of the MSM element.

8. The device of claim 1 , further comprising:
an upper body, wherein the channel is defined within the upper body; and
a lower body configured to attach to the upper body, wherein the MSM element is attached to the lower body, wherein the membrane is a film attached to the lower body and covering the MSM element, wherein a pressure fit between the film and the upper body seals the channel when the upper body and the lower body are attached, and wherein the MSM element deforms the channel at the portions of the flexible membrane that are adjacent to the non-contracted portions of the MSM element by compressing the membrane between an inner surface of the channel and the MSM element.

9. The device of claim 8 , wherein the film is an adhesive tape and holds the MSM element in place.

10. The device of claim 8 , further comprising a second membrane positioned between the MSM element and the lower body.

11. A magnetic shape memory (MSM) actuation method comprising:
exposing a first portion of an MSM element, having a dimension, to a first component of a magnetic field, the first component substantially parallel to the dimension, to contract the MSM element across the dimension at the first portion;
exposing a second portion of the MSM element to a second component of the magnetic field, the second component not substantially parallel to the dimension, to un-contract the MSM element across the dimension at the second portion;
engaging a flexible membrane to deform a channel at portions of the flexible membrane that are adjacent to the MSM element; and
preventing contact between a fluid and the MSM element using the flexible membrane.

12. The method of claim 11 , further comprising:
engaging the flexible membrane to enable a cavity to form at portions of the flexible membrane that are adjacent to contracted portions of the MSM element.

13. The method of claim 12 , further comprising:
moving the first component and second component of the magnetic field along the MSM element to result in movement of the cavity.

14. The method of claim 11 , wherein the flexible membrane is incorporated into an upper body, wherein the MSM element is incorporated into a lower body, the method further comprising:
interchanging the upper body with at least one additional upper body wherein at least one additional upper body comprises an additional flexible membrane.

15. The method of claim 11 , wherein the flexible membrane includes an inert material such as polyvinylchloride (PVC), polyethersulfone (PES), polytetrafluoroethylene (PTFE), low-density-polyethylene (PE-LD), high-density-polyethylene (PE-HD), ultra-high-molecular-weight polyethylene (PE-UHMW), polyurethane (PU), polyetherimide (PEI), polycarbonate (PC), polysulfone (PS), polyetheretherketone (PEEK), polypropylene (PP), polytetrafluoroethylene (PTFE, Teflon), or any combination thereof.

16. A method comprising:
forming an upper body from an inert material;
positioning a film adjacent to a surface of the upper body;
bonding the film to the upper body along a first portion of the surface of the upper body while refraining from bonding the film to the upper body along a second portion of the surface to define a channel between the surface of the upper body and the film; and
forming a lower body configured to attach to the upper body, wherein an MSM element is positioned between the upper body and the lower body when the lower body is attached to the upper body, and

Assignees

• Univ Boise State

Inventors

• Mullner Peter
• Johnston Geoffrey Brent
• Smith Aaron
• Armstrong Andrew

Classifications

• B01L3/50273 Primary

  characterised by the means or forces applied to move the fluids · CPC title

• B01L3/502707

  characterised by the manufacture of the container or its components · CPC title

• B01L2200/12

  Specific details about manufacturing devices · CPC title

• B01L2300/0681

  Filter · CPC title

• B01L2300/123

  Flexible; Elastomeric · CPC title