Functionalized balloon surface

Patent metadata

Field	Value
Publication number	US-11771874-B2
Application number	US-202017619660-A
Country	US
Kind code	B2
Filing date	Jun 23, 2020
Priority date	Jul 2, 2019
Publication date	Oct 3, 2023
Grant date	Oct 3, 2023

Abstract

A method for producing a balloon for a balloon catheter includes providing the balloon that has an outer surface. A solution including a solvent and a polymer is used to deposit the polymer onto the surface and form a surface coating of the polymer.

First claim

The invention claimed is:

1. A method for producing a balloon for a balloon catheter, comprising the following steps:
providing the balloon, wherein the balloon has an outer surface;
providing a solution comprising a solvent and a polymer dissolved in the solution; and
depositing the polymer onto the surface from the solution to form a surface coating of the polymer on the surface of the balloon, wherein the solvent and polymer are selected such that fibrous particles are deposited on the surface in gel-like form, and the particles undergo a loss of volume due to the drying after application and due to suctioning or solvent-withdrawing action of the balloon surface.

2. The method according to claim 1 , wherein the solvent is trifluoroacetic acid.

3. The method according to claim 2 , wherein the polymer is selected from the group consisting of: an aliphatic or aromatic polyamide and a thermoplastic polymer.

4. The method according to claim 3 , wherein the polymer in the solution has a concentration in the range of 1 wt. % to 30 wt. %.

5. The method according to claim 3 , wherein the polymer is a thermoplastic elastomer-modified polymer.

6. The method according to claim 3 , wherein the polymer is a polyether block amide.

7. The method according to claim 1 , wherein the polymer of the solution is deposited onto the surface by electrospinning.

8. The method according to claim 1 , wherein the balloon comprises one of an aliphatic or aromatic polyamide or a thermoplastic elastomer-modified polymer.

9. The method according to claim 1 , further comprising adding a drug or a composition containing a drug on the surface coating.

10. The method according to claim 1 , wherein the balloon comprises at least one electrical conductor on the surface of the balloon prior to the deposition of the polymer, the generated surface coating embeds the at least one conductor.

11. The method according to claim 1 , wherein the depositing comprises spraying through a shaped nozzle and wherein the solvent and polymer are selected such that the viscosity of the solution creates thread-shaped fragments in a spray from the nozzle that are preserved in the gas phase due to solvent loss.

12. The method according to claim 11 , wherein the solution emerges in a thread-like manner from the nozzle.

Assignees

• Biotronik Ag

Inventors

• Quint Bodo
• Wernli Jeremy

Classifications

• A61M25/1029 Primary

  Production methods of the balloon members, e.g. blow-moulding, extruding, deposition or by wrapping a plurality of layers of balloon material around a mandril · CPC title

• D01D5/003

  the material being a polymer solution or dispersion (D01D5/0053 takes precedence) · CPC title

• A61M2025/105

  having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes · CPC title

• A61M2025/1031

  Surface processing of balloon members, e.g. coating or deposition; Mounting additional parts onto the balloon member's surface · CPC title

• A61M2025/1075

  having a balloon composed of several layers, e.g. by coating or embedding · CPC title