Filtering apparatus comprising an integrated flow reducer, and method for completely imbibing a filter membrane

Patent metadata

Field	Value
Publication number	US-11759733-B2
Application number	US-201816635835-A
Country	US
Kind code	B2
Filing date	Jul 24, 2018
Priority date	Aug 1, 2017
Publication date	Sep 19, 2023
Grant date	Sep 19, 2023

Abstract

A filtration device, in particular a disposable filtration device, has a flow path in which a filter element and an integrated flow reducer are arranged one behind the other. The flow reducer is adapted to be brought to a first operating position, which permits a defined first volume flow rate, and at least to a second operating position, which permits a defined second volume flow rate which is smaller than the first volume flow rate.

First claim

The invention claimed is:

1. A filtration device, comprising
a flow path in which a filter element and a flow reducer are arranged one behind the other, the flow reducer being adapted to be brought to a first operating position, which permits a defined first volume flow rate, and at least to a second operating position, which permits a defined second volume flow rate which is smaller than the first volume flow rate, wherein a ratio between the second volume flow rate and the first volume flow rate is between 0.05 and 0.9,
the flow reducer comprising an adjustable control element, which in the first operating position of the flow reducer assumes a defined first position, in which it exposes a first effective flow cross-section, and in the second operating position of the flow reducer assumes a defined second position, in which it exposes a second effective flow cross section, which is smaller than the first effective flow cross-section,
wherein the control element is adapted to be moved to the defined positions by means of a rotating mechanism,
wherein the control element comprises a cylindrical body movable in a pipe section of the flow reducer and having a cylindrical passage extending through the body that is oriented in a flow direction in the first position of the control element and substantially transversely to the flow direction in the second position of the control element.

2. The filtration device according to claim 1 , characterized in that the filtration device is a disposable filtration device.

3. The filtration device according to claim 1 , characterized in that the flow reducer is integrated in the filtration device.

4. The filtration device according to claim 1 , characterized in that the flow reducer consists entirely of materials that are sterilizable.

5. The filtration device according to claim 1 , characterized in that the ratio between the second volume flow rate and the first volume flow rate is between 0.05 and 0.5.

6. The filtration device according to claim 1 , characterized by a control device by means of which the control element can be moved to the first position and to the second position in an automated manner.

7. The filtration device according to claim 1 , characterized in that the control element can assume further defined positions in addition to the first and second positions.

8. The filtration device according to claim 1 , characterized in that the defined positions of the control element are configured as detent positions.

9. The filtration device according to claim 8 , characterized in that the control element is adapted to be transferred to the detent positions by means of a pretensioned actuating element.

10. The filtration device according to claim 9 , characterized by a protective covering which surrounds the rotating mechanism and, if required, the pretensioned actuating element.

11. The filtration device according to claim 1 , characterized in that the body and the passage of the control element in the second position provide sickle-shaped passage ducts.

12. The filtration device according to claim 1 , characterized in that the pipe section of the flow reducer comprises a main pipe section having a first valve as the control element and a bypass pipe section for bypassing the first valve, the flow cross-section of the bypass pipe section being smaller than the flow cross-section of the main pipe section.

13. The filtration device according to claim 12 , characterized in that a second valve is provided in the bypass pipe section.

14. The filtration device according to claim 13 , characterized in that the first valve and/or the second valve is/are adapted to assume a plurality of positions in which different flow cross-sections are exposed.

15. A method of completely wetting a filter membrane in the filtration device according to claim 1 within a scope of a flushing process, characterized in that the flow reducer is in the second operating position, which permits a defined second volume flow rate, which is smaller than the first volume flow rate, so that the flushing of the filter element is effected with a reduced volume in order to completely wet the filter membrane, wherein the flow reducer is brought to the first operating position after the flushing process for carrying out a filtration process.

16. The method according to claim 15 , characterized in that the complete wetting of the filter membrane is performed while saving flushing medium by 10 to 95% in comparison with the complete wetting without pressure reduction.

Assignees

• Sartorius Stedim Biotech Gmbh

Inventors

• Thom Volkmar
• Loewe Thomas
• Handt Sebastian
• Sommer Maik

Classifications

• B01D65/10

  Testing of membranes or membrane apparatus; Detecting or repairing leaks · CPC title

• B01D61/20 Primary

  Accessories; Auxiliary operations · CPC title

• B01D29/668 Primary

  with valves, e.g. rotating valves for coaxially placed filtering elements · CPC title

• B01D35/1576

  Calibrated passages · CPC title

• B01D46/4272

  Special valve constructions adapted to filters or filter elements · CPC title