Immunostimulating IL-2 analogs

US11746137B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-11746137-B2
Application numberUS-202117915808-A
CountryUS
Kind codeB2
Filing dateMar 31, 2021
Priority dateMar 31, 2020
Publication dateSep 5, 2023
Grant dateSep 5, 2023

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present invention relates to changes in interleukin-2 alpha receptors and interleukin-2 analogs with increased binding affinity for interleukin-2 beta receptors.

First claim

Opening claim text (preview).

The invention claimed is: 1. An interleukin-2 analog comprising any one sequence selected from the group consisting of the amino acid sequences of SEQ ID NOs: 22, 53, 87, 89, 91, 99, 104, 105, and 106.

Assignees

Inventors

Classifications

  • Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression · CPC title

  • Medicinal preparations containing peptides (peptides containing beta-lactam rings A61K31/00; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, A61K31/00; ergot alkaloids of the cyclic peptide type A61K31/48; containing macromolecular compounds having statistically distributed amino acid units A61K31/74; medicinal preparations containing antigens or antibodies A61K39/00; medicinal preparations characterised by the non-active ingredients, e.g. peptides as drug carriers, A61K47/00) · CPC title

  • Interleukin · CPC title

  • C12N15/70Primary

    Vectors or expression systems specially adapted for E. coli · CPC title

  • C07K14/55Primary

    IL-2 · CPC title

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Frequently asked questions

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What does patent US11746137B2 cover?
The present invention relates to changes in interleukin-2 alpha receptors and interleukin-2 analogs with increased binding affinity for interleukin-2 beta receptors.
Who is the assignee on this patent?
Hanmi Pharm Ind Co Ltd
What technology area does this patent fall under?
Primary CPC classification C12N15/70. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).