Novel sesquiterpenoid stat3 inhibitors
US-2016137663-A1 · May 19, 2016 · US
US11746120B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11746120-B2 |
| Application number | US-202218045390-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 10, 2022 |
| Priority date | Apr 5, 2019 |
| Publication date | Sep 5, 2023 |
| Grant date | Sep 5, 2023 |
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The present invention provides compounds, compositions thereof, and methods of using the same.
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We claim: 1. A compound selected from the group consisting of: or a pharmaceutically acceptable salt thereof. 2. The compound of claim 1 , wherein said compound is or a pharmaceutically acceptable salt thereof. 3. The compound of claim 1 , wherein said compound is or a pharmaceutically acceptable salt thereof. 4. The compound of claim 1 , wherein said compound is or a pharmaceutically acceptable salt thereof. 5. The compound of claim 1 , wherein said compound is or a pharmaceutically acceptable salt thereof. 6. The compound of claim 1 , wherein said compound is or a pharmaceutically acceptable salt thereof. 7. The compound of claim 1 , wherein said compound is or a pharmaceutically acceptable salt thereof. 8. The compound of claim 1 , wherein said compound is or a pharmaceutically acceptable salt thereof. 9. The compound of claim 1 , wherein said compound is or a pharmaceutically acceptable salt thereof. 10. The compound of claim 1 , wherein said compound is or a pharmaceutically acceptable salt thereof. 11. The compound of claim 1 , wherein said compound is or a pharmaceutically acceptable salt thereof. 12. The compound of claim 1 , wherein said compound is or a pharmaceutically acceptable salt thereof. 13. The compound of claim 1 , wherein said compound is or a pharmaceutically acceptable salt thereof. 14. The compound of claim 1 , wherein said compound is or a pharmaceutically acceptable salt thereof. 15. The compound of claim 1 , wherein said compound is or a pharmaceutically acceptable salt thereof. 16. The compound of claim 1 , wherein said compound is or a pharmaceutically acceptable salt thereof. 17. The compound of claim 1 , wherein said compound is or a pharmaceutically acceptable salt thereof. 18. The compound of claim 1 , wherein said compound is or a pharmaceutically acceptable salt thereof. 19. The compound of claim 1 , wherein said compound is or a pharmaceutically acceptable salt thereof. 20. The compound of claim 1 , wherein said compound is or a pharmaceutically acceptable salt thereof. 21. The compound of claim 1 , wherein said compound is or a pharmaceutically acceptable salt thereof. 22. The compound of claim 1 , wherein said compound is or a pharmaceutically acceptable salt thereof. 23. The compound of claim 1 , wherein said compound is or a pharmaceutically acceptable salt thereof. 24. The compound of claim 1 , wherein said compound is or a pharmaceutically acceptable salt thereof. 25. The compound of claim 1 , wherein said compound is or a pharmaceutically acceptable salt thereof. 26. A pharmaceutical composition comprising a compound selected from the group consisting of: or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant, or vehicle. 27. The pharmaceutical composition of claim 26 , wherein said compound is selected from the group consisting of: or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant, or vehicle. 28. The pharmaceutical composition of cla
Medicinal preparations containing peptides (peptides containing beta-lactam rings A61K31/00; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, A61K31/00; ergot alkaloids of the cyclic peptide type A61K31/48; containing macromolecular compounds having statistically distributed amino acid units A61K31/74; medicinal preparations containing antigens or antibodies A61K39/00; medicinal preparations characterised by the non-active ingredients, e.g. peptides as drug carriers, A61K47/00) · CPC title
specific for leukemia · CPC title
Antineoplastic agents · CPC title
the side chain containing 2 to 4 carbon atoms · CPC title
containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings · CPC title
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