Ablation catheters

Patent metadata

Field	Value
Publication number	US-11744639-B2
Application number	US-201916379140-A
Country	US
Kind code	B2
Filing date	Apr 9, 2019
Priority date	Nov 11, 2008
Publication date	Sep 5, 2023
Grant date	Sep 5, 2023

Abstract

Cardiac tissue ablation catheters including an inflatable and flexible toroidal or spherically shaped balloon disposed at a distal region of an elongate member, a flexible circuit carried by an outer surface of the balloon, the flexible circuit including, a plurality of flexible branches conforming to the radially outer surface of the balloon, each of the plurality of flexible branches including a substrate, a conductive trace carried by the substrate, and an ablation electrode carried by the substrate, the ablation electrode in electrical communication with the conductive trace, and an elongate shaft comprising a guidewire lumen extending in the elongate member and extending from a proximal region of the inflatable balloon to distal region of the inflatable balloon and being disposed within the inflatable balloon, wherein a distal region of the elongate shaft is secured directly or indirectly to the distal region of the inflatable balloon.

First claim

What is claimed is:

1. A cardiac tissue ablation apparatus comprising:
an elongate member;
a membrane forming an inflatable balloon having a proximal region and a distal region, the proximal region attached to the distal portion of the elongate member, the distal region terminating at a balloon distal end;
a shaft having a guidewire lumen and a longitudinal axis extending through the elongate member and the balloon, the shaft having a distal region secured directly or indirectly to the distal region of the balloon;
an electrode assembly comprising:
a plurality of flexible branches attached to an outer surface of the balloon, the flexible branches extending from the balloon distal end to the proximal region of the balloon; and
a plurality of ablation electrodes, each one of the plurality of ablation electrodes carried by one of the plurality of branches; and

a mapping catheter extendable through the guidewire lumen, the mapping catheter including a loop portion including a plurality of mapping electrodes, the mapping catheter being configured so that the loop portion can be located distally of the balloon distal end in use,
wherein each of the plurality of ablation electrodes has a proximal end and a distal end, wherein each of the plurality of ablation electrodes has a width that increases from the proximal end to a greatest width and then decreases from the greatest width to the distal end, wherein the decrease in width of the ablation electrode from the greatest width to the distal end is more gradual than is the increase in the width from the proximal end to the greatest width, wherein a length of each of the plurality of ablation electrodes from the greatest width to the distal end is greater than a length of the ablation electrode from the proximal end to the greatest width.

2. The cardiac tissue ablation apparatus of claim 1 , wherein the plurality of flexible branches each carry an electrical conductor operatively coupled to a respective one of the ablation electrodes.

3. The cardiac tissue ablation apparatus of claim 2 , wherein the plurality of flexible branches each form a flex circuit having a substrate and an electrical trace on the substrate defining the electrical conductor.

4. The cardiac tissue ablation apparatus of claim 2 , further comprising a plurality of irrigation holes in the membrane proximate the ablation electrodes, the irrigation holes configured to pass irrigation fluid from an interior of the balloon.

5. The cardiac tissue ablation apparatus of claim 2 , further comprising a plurality of irrigation holes in the ablation electrodes and the membrane, the irrigation holes configured to pass irrigation fluid from an interior of the balloon.

6. The cardiac tissue ablation apparatus of claim 1 , wherein in a view directed orthogonally to the longitudinal axis of the shaft, proximal ends of all of the plurality of ablation electrodes are disposed in a first plane orthogonal to the longitudinal axis of the shaft, and distal ends of all of the plurality of ablation electrodes are disposed in a second plane orthogonal to the longitudinal axis of the shaft, the second plane being different from the first plane.

7. The cardiac tissue ablation apparatus of claim 1 , wherein the ablation electrodes are configured to conform to a shape of the balloon when the balloon is in an inflated state.

8. The cardiac tissue ablation apparatus of claim 1 , wherein all of the plurality of flexible branches are joined to form a unitary structure proximate the balloon distal end.

9. The cardiac tissue ablation apparatus of claim 8 , wherein the shaft is axially movable relative to the elongate member such that movement of the shaft can modify the shape of the balloon.

10. The cardiac tissue ablation apparatus of claim 1 , wherein the loop portion of the mapping catheter is configured to conform to an inside surface of a pulmonary vein when in use.

11. The cardiac tissue ablation apparatus of claim 10 , wherein the mapping catheter is operable as a guidewire.

12. A cardiac tissue ablation apparatus comprising:
an ablation catheter comprising:
an inflatable balloon having a proximal region and a distal region, the distal region terminating at a balloon distal end;
a shaft having a guidewire lumen and a longitudinal axis extending through the balloon, the shaft having a distal region secured directly or indirectly to the distal region of the balloon;
an electrode assembly comprising:
a plurality of flexible branches attached to an outer surface of the balloon, the flexible branches extending from the balloon distal end to the proximal region of the balloon; and
a plurality of ablation electrodes, each one of the plurality of ablation electrodes carried by one of the plurality of branches; and
a plurality of irrigation holes in the ablation electrodes configured to pass irrigation fluid from an interior of the balloon; and

a mapping catheter extendable through the guidewire lumen, the mapping catheter including a loop portion including a plurality of mapping electrodes, the mapping catheter being configured so that the loop portion can be located distally of the balloon distal end in use, wherein the mapping catheter is operable as a guidewire,
wherein each of the plurality of ablation electrodes has a proximal end and a distal end, and wherein each of the plurality of ablation electrodes has a width that increases from the proximal end to a greatest width and then decreases from the greatest width to the distal end, wherein the decrease in width of the ablation electrode from the greatest width to the distal end is more gradual than is the increase in the width from the proximal end to the greatest width, wherein a length of each of the plurality of ablation electrodes from the greatest width to the distal end is greater than a length of the ablation electrode from the proximal end to the greatest width.

13. The cardiac tissue ablation apparatus of claim 12 , wherein the loop portion of the mapping catheter is configured to conform to an inside surface of a pulmonary vein when in use.

14. The cardiac tissue ablation apparatus of claim 13 , wherein the ablation electrodes are configured to conform to a shape of the balloon when the balloon is in an inflated state.

15. The cardiac tissue ablation apparatus of claim 14 , wherein the plurality of flexible branches each carry an electrical conductor operatively coupled to a respective one of the ablation electrodes.

16. The cardiac tissue ablation apparatus of claim 15 , wherein the plurality of flexible branches each form a flex circuit having a substrate and an electrical trace on the substrate defining the electrical conductor.

17. The cardiac tissue ablation apparatus of claim 12 , wherein in a view directed orthogonally to the longitudinal axis of the shaft, proximal ends of all of the plurality of ablation electrodes are disposed in a first plane orthogonal to the longitudinal axis of the shaft, and distal ends of all of the plurality of ablation electrodes are disposed in a second plane orthogonal to the longitudinal axis of the shaft, the second plane being different from the first plane.

18. The cardiac tissue ablation apparatus of claim 14 , wherein all of the plurality of flexible branches are joined to form a unitary structure proximate the balloon distal end.

Assignees

• Shifamed Holdings Llc

Inventors

• Salahieh Amr
• Lepak Jonah
• Lepak Emma
• Brandt Brian D
• Claude John P
• Saul Tom

Classifications

• A61B18/1492 Primary

  having a flexible, catheter-like structure, e.g. for heart ablation (A61B18/1477 takes precedence) · CPC title

• A61B1/00082

  Balloons · CPC title

• A61B1/00179

  for off-axis viewing · CPC title

• A61B1/0623

  for off-axis illumination · CPC title

• A61B5/287

  Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS] · CPC title