Devices and methods for locating and implanting tissue anchors at mitral valve commissure

Patent metadata

Field	Value
Publication number	US-11744573-B2
Application number	US-202117173883-A
Country	US
Kind code	B2
Filing date	Feb 11, 2021
Priority date	Aug 31, 2013
Publication date	Sep 5, 2023
Grant date	Sep 5, 2023

Abstract

A system is transluminally advanced into the heart of a subject. A first portion of the system is positioned through a native valve of the heart, the system including wires disposed at the first portion. The first portion is stabilized at the native valve by positioning a distal portion of the system within a blood vessel of the subject. While the distal portion of the system remains within the blood vessel, the wires are induced to bow laterally such that the wires press against the native valve. While the wires remain pressed against the native valve, the shape of the wires is radiographically imaged. An anchor is transluminally anchored to tissue of the native valve, facilitated by the imaging. Other embodiments are also described.

First claim

The invention claimed is:

1. A method for use at a mitral valve of a heart of a subject, the method comprising:
transluminally advancing a system into the heart;
positioning a first portion of the system through the mitral valve, the system including wires disposed at the first portion;
stabilizing the first portion at the mitral valve by positioning a distal portion of the system within a pulmonary vein of the subject;
while the distal portion of the system remains within the pulmonary vein, inducing the wires to bow laterally such that the wires press against the mitral valve;
while the wires remain pressed against the mitral valve, radiographically imaging a shape of the wires; and
transluminally anchoring an anchor to tissue of the mitral valve, facilitated by the imaging.

2. The method according to claim 1 , wherein, for each of the wires, a first segment of the wire is disposed at the first portion and a second segment of the wire is disposed at the distal portion, and wherein inducing the wires to bow laterally comprises inducing the wires to bow laterally such that the second segment of each of the wires moves laterally and secures the distal portion inside the pulmonary vein.

3. The method according to claim 1 , wherein:
the wires are first wires,
the system includes second wires disposed at the distal portion, and
positioning the distal portion within the pulmonary vein comprises positioning the second wires within the pulmonary vein.

4. The method according to claim 3 , wherein the method further includes securing the distal portion inside the pulmonary vein by inducing the second wires to bow laterally within the pulmonary vein.

5. The method according to claim 1 , wherein inducing the wires to bow laterally such that the wires press against the mitral valve comprises inducing the wires to bow laterally such that the wires press against commissures of the mitral valve.

6. The method according to claim 1 , wherein the system includes exactly two wires, and wherein inducing the wires to bow laterally such that the wires press against the mitral valve comprises inducing the exactly two wires to bow laterally such that the exactly two wires press against the mitral valve.

7. The method according to claim 1 , wherein:
the system includes a bow catheter, and a central catheter that is slidably disposed within a lumen of the bow catheter,
each of the wires has a first end attached to the bow catheter, and a second end attached to the central catheter, and
inducing the wires to bow laterally comprises inducing the wires to bow laterally by sliding the central catheter with respect to the bow catheter.

8. The method according to claim 7 , wherein positioning the first portion of the system through the mitral valve comprises positioning the first portion of the system such that the first end of each of the wires is disposed downstream of the mitral valve, and the second end of each of the wires is disposed upstream of the mitral valve.

9. The method according to claim 7 , wherein inducing the wires to bow laterally by sliding the central catheter with respect to the bow catheter comprises inducing the wires to bow laterally by retracting the central catheter into the bow catheter.

10. The method according to claim 1 , further comprising transluminally advancing a delivery catheter to the heart, and delivering the anchor to the mitral valve via the delivery catheter.

11. The method according to claim 10 , further comprising tracking the delivery catheter along one of the wires.

12. The method according to claim 1 , wherein anchoring the anchor comprises anchoring the anchor at a posteromedial commissure of the mitral valve.

13. The method according to claim 1 , wherein anchoring the anchor comprises anchoring the anchor at an anterolateral commissure of the mitral valve.

14. The method according to claim 1 , wherein the anchor is a first anchor, and wherein the method further comprises transluminally anchoring a second anchor to tissue of the mitral valve, facilitated by the imaging.

15. The method according to claim 14 , wherein anchoring the first anchor comprises anchoring the first anchor at an anterolateral commissure of the mitral valve, and wherein anchoring the second anchor comprises anchoring the second anchor at a posteromedial commissure of the mitral valve.

16. The method according to claim 14 , further comprising, subsequently to anchoring the first and second anchors, transluminally reducing a distance between the first and second anchors by applying tension to a tensile member that is coupled to the first and second anchors.

17. The method according to claim 16 , further comprising locking the tension in the tensile member by locking a locker to the tensile member.

18. The method according to claim 17 , further comprising, prior to locking the locker to the tensile member, advancing the locker along the tensile member toward the first and second anchors.

19. The method according to claim 17 , further comprising, subsequently to locking the locker to the tensile member, using a cutter to remove excess of the tensile member.

20. The method according to claim 1 , wherein the system includes a catheter, the wires disposed laterally from the catheter, and wherein positioning the first portion of the system through the mitral valve comprises positioning the system such that the catheter extends through the mitral valve.

21. The method according to claim 1 , wherein inducing the wires to bow laterally such that the wires press against the mitral valve comprises inducing the wires to bow laterally until the wires form a waist at the mitral valve.

22. The method according to claim 1 , wherein the pulmonary vein is a left pulmonary vein of the subject, and wherein positioning the distal portion within the pulmonary vein comprises positioning the distal portion within the left pulmonary vein.

23. A method for use at a native valve of a heart of a subject, the method comprising:
transluminally advancing a system into the heart;
positioning a first portion of the system through the native valve, the system including wires disposed at the first portion;
stabilizing the first portion at the native valve by positioning a distal portion of the system within a blood vessel of the subject;
while the distal portion of the system remains within the blood vessel, inducing the wires to bow laterally such that the wires press against the native valve;
while the wires remain pressed against the native valve, radiographically imaging a shape of the wires; and
transluminally anchoring an anchor to tissue of the native valve, facilitated by the imaging.

24. The method according to claim 23 , wherein, for each of the wires, a first segment of the wire is disposed at the first portion and a second segment of the wire is disposed at the distal portion, and wherein inducing the wires to bow laterally comprises inducing the wires to bow laterally such that the second segment of each of the wires moves laterally and secures the distal portion inside the blood vessel.

25. The method according to claim 23 , wherein:
the wires are first wires,
the system includes second wires disposed at the distal portion,
positioning the distal portion within the blood vessel comprises positioning the second wires within the blood vessel, and
the method further comprises securing the distal portion inside the blood vessel by indu

Assignees

• Edwards Lifesciences Corp

Inventors

• Alexander John
• Holmes Megan E
• Hudson Richard D
• Lee Christopher C
• Cahalane Steven D

Classifications

• A61B17/0401 Primary

  Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors (A61B17/0642 takes precedence; fixation devices for tendons or ligaments A61F2/0811) · CPC title

• A61B18/1492

  having a flexible, catheter-like structure, e.g. for heart ablation (A61B18/1477 takes precedence) · CPC title

• A61B2017/003

  Steerable · CPC title

• A61B2017/00243

  cardiac · CPC title

• A61B2017/00783

  Valvuloplasty · CPC title