Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals

Patent metadata

Field	Value
Publication number	US-11738327-B2
Application number	US-202217725830-A
Country	US
Kind code	B2
Filing date	Apr 21, 2022
Priority date	Nov 6, 2017
Publication date	Aug 29, 2023
Grant date	Aug 29, 2023

Abstract

The invention relates to strong hydrogen-bond acidic sorbents. The sorbents may be provided in a form that limits or eliminates intramolecular bonding of the hydrogen-bond acidic site between neighboring sorbent molecules, for example, by providing steric groups adjacent to the hydrogen-bond acidic site. The hydrogen bond site may be a phenolic structure based on a bisphenol architecture. The sorbents of the invention may be used in methods for trapping or detecting hazardous chemicals or explosives.

First claim

What is claimed:

1. A method for separating a hydrogen-bond basic analyte from a mixture, the method comprising:
coating a bisphenol sorbent comprising a compound of formula I or formula II as a chromatographic stationary phase,

wherein
R 1 is selected from the group consisting of prop-1-en-2-yl; -dimethyl(phenyl)silyl; trimethylsilyl; diphenylmethyl; methylthio; prop-2-enyl; benzyl; ethylthio; cyclopropyl; 2-(trimethylsilyl)ethyl; 2,2-dimethylpropyl; 2-methylpropyl; phenylethyl; propyl; butyl; sec-butyl; pentyl; heptyl; propan-2-yl; cyclopentyl; cyclohexyl; cyclobutyl; 3-ethylpentan-3-yl; ethyl; 1,1-dimethylpropyl; (trimethylsilyl)methyl; trifluoromethyl; and fluoro; and
R 2 is selected from the group consisting of, methyl; tert-butyl; prop-1-en-2-yl; dimethyl(phenyl)silyl; trimethylsilyl; diphenylmethyl; methylthio; prop-2-enyl; benzyl; ethylthio; cyclopropyl; 2-(trimethylsilyl)ethyl; 2,2-dimethylpropyl; 2-methylpropyl; phenylethyl; propyl; butyl; sec-butyl; pentyl; heptyl; propan-2-yl; cyclopentyl; cyclobutyl; 3-ethylpentan-3-yl; ethyl; 1,1-dimethylpropyl; (trimethylsilyl)methyl; trifluoromethyl; and fluoro; and
contacting the chromatographic stationary phase coated with bisphenol sorbent with a sample comprising a hydrogen-bond basic analyte, wherein the bisphenol sorbent selectively binds with hydrogen-bond basic analytes having higher hydrogen-bond basicity over other chemicals having lower hydrogen-bond basicity, resulting in separation of the analyte from other components in the sample.

Assignees

• Us Gov Sec Navy

Inventors

• Mcgill R Andrew
• Roberts Courtney A

Classifications

• B01J20/22 Primary

  comprising organic material · CPC title

• B01J20/281

  Sorbents specially adapted for preparative, analytical or investigative chromatography · CPC title

• B01J20/282

  Porous sorbents (ion exchange B01J39/00 - B01J41/00) · CPC title

• B01J20/28023

  Fibres or filaments (fibres or filaments in the form of membranes B01J20/28038; B01J20/28007 takes precedence) · CPC title

• B01J20/3425

  of sorbents or filter aids comprising organic materials · CPC title