Phantom for quantitative diffusion magnetic resonance imaging
US-2016363644-A1 · Dec 15, 2016 · US
US11733334B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11733334-B2 |
| Application number | US-201917252753-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 17, 2019 |
| Priority date | Jun 19, 2018 |
| Publication date | Aug 22, 2023 |
| Grant date | Aug 22, 2023 |
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A method of magnetic resonance (MR) imaging includes a phantom that is inexpensive to produce and enables simple, practical and fast assessment of image sharpness, in particular for checking image quality of MR imaging with spiral acquisition. The method includes subjecting a phantom, which comprises a volume filled with a bulk of granules of solid material surrounded by a liquid, to an imaging sequence, acquiring MR signals from the phantom, reconstructing an MR image from the acquired MR signals, and deriving a measure of the local image sharpness in two or more different image regions from the MR image, wherein each image region is a representation of a part of the phantom volume.
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The invention claimed is: 1. A method of assessment of image quality of a magnetic resonance (MR) image, the method comprising: providing a phantom, which comprises a volume filled with a bulk of granules of solid material surrounded by a liquid, the granules' material's paramagnetic susceptibility being essentially equal to a surrounding liquid's paramagnetic susceptibility, subjecting the phantom to an imaging sequence, acquiring MR signals from the phantom, reconstructing an MR image from the acquired MR signals, and deriving a measure of sharpness associated with off-resonance effects of the MR image due to main magnetic field inhomogeneities and to deviations of gradient magnetic fields in two or more different image regions from the MR image, wherein each image region is a representation of a different part of the phantom volume. 2. The method of claim 1 , wherein a diameter of the granules is two to five times larger than a voxel size of the MR image. 3. The method of claim 1 , wherein the granules are spherical and of essentially equal size. 4. The method of claim 1 , wherein the granules are randomly packed in the phantom volume. 5. The method of claim 1 , wherein the material of the granules contains no nuclei contributing to the MR signals. 6. The method of claim 1 , wherein a transverse relaxation time of the contribution from the material of the granules to the MR signals is significantly shorter than the transverse relaxation time of a contribution from the surrounding liquid to the MR signals. 7. The method of claim 1 , wherein the phantom volume is of a spherical shape. 8. The method of claim 1 , wherein the surrounding liquid is free of dissolved gas. 9. The method of claim 1 , wherein the material of the granules is a plastic. 10. The method of claim 1 , wherein the surrounding liquid is any of water with ions dissolved therein. 11. The method of claim 10 , wherein the ions include at least one selected from a group consisting of copper, nickel or manganese ions, a carbohydrate. 12. The method of claim 1 , wherein the imaging sequence comprises at least one RF excitation pulse and modulated magnetic field gradients, wherein the MR signals are acquired along at least one spiral k-space trajectory. 13. The method of claim 1 , wherein the imaging sequence comprises a number of RF excitation pulses and a number of magnetic field gradients applied in different directions, wherein the MR signals are acquired along a number of radial k-space trajectories. 14. The method of claim 1 , wherein the measure of the image sharpness is derived by computing an average voxel value and a standard deviation of the voxel values for each of the image regions and by computing a ratio of the standard deviation and the average voxel value for each of the image regions. 15. The method of claim 1 , wherein deviations of the gradient magnetic fields includes at least one of gradient non-linearities or gradient delays. 16. The method of claim 1 , wherein a diameter of the granules is three to four times larger than a voxel size of the MR image. 17. The method of claim 1 , wherein the material of the granules is a is at least one selected from a group consisting of: polyethylene or polymethyl methacrylate.
Signal processing systems, e.g. using pulse sequences {; Generation or control of pulse sequences; Operator console} · CPC title
using a non-Cartesian trajectory · CPC title
Calibration of imaging systems, e.g. using test probes {, Phantoms; Calibration objects or fiducial markers such as active or passive RF coils surrounding an MR active material} · CPC title
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