Blood treatment systems

Patent metadata

Field	Value
Publication number	US-11730871-B2
Application number	US-202017092935-A
Country	US
Kind code	B2
Filing date	Nov 9, 2020
Priority date	Nov 12, 2019
Publication date	Aug 22, 2023
Grant date	Aug 22, 2023

Abstract

Dialyzer systems can consolidate multiple technologies and functionalities of blood treatment systems in a significantly integrated fashion. For example, this disclosure describes dialyzer systems that include a magnetically driven and magnetically levitating pump rotor integrated into the dialyzer. Such a dialyzer can be used with treatment modules that include a magnetic field-generating pump drive unit. In some embodiments, the dialyzers include pressure sensor chambers with flexible membranes with which corresponding pressure transducers of the treatment modules can interface to detect arterial and/or venous pressures.

First claim

What is claimed is:

1. A dialyzer comprising:
a housing;
a bundle of hollow fibers within an interior of the housing; and
a pump impeller within the housing, the pump impeller being magnetically-drivable to force fluid through lumens of the hollow fibers,
wherein the housing comprises a first end cap defining an incoming fluid flow path to the pump impeller that enters the first end cap transverse to a longitudinal axis of the housing and transitions to parallel to the longitudinal axis of the housing to deliver the fluid to the pump impeller.

2. The dialyzer of claim 1 , wherein the incoming fluid flow path is configured to deliver the fluid to a center of the pump impeller.

3. The dialyzer of claim 2 , wherein the pump impeller is centrifugal such that the fluid delivered to the center of the pump impeller is forced radially outward and then longitudinally along the first end cap and into the lumens of the hollow fibers when the pump impeller is rotated.

4. The dialyzer of claim 1 , wherein the first end cap defines a first dialysate port in fluid communication with the interior of the housing external to the lumens of the hollow fibers.

5. The dialyzer of claim 4 , wherein the first end cap defines a first substituate liquid port in fluid communication with the incoming fluid flow path.

6. The dialyzer of claim 5 , further comprising a check valve arranged to prevent the fluid from exiting the first substituate liquid port.

7. The dialyzer of claim 5 , wherein the housing further comprises a second end cap that defines an outgoing fluid flow path for the fluid to exit the housing after passing through the lumens of the hollow fibers, and wherein the second end cap defines: (i) a second substituate liquid port in fluid communication with the outgoing fluid flow path and (ii) a second dialysate port in fluid communication with the interior of the housing external to the lumens of the hollow fibers.

8. The dialyzer of claim 7 , further comprising a check valve along the outgoing fluid flow path.

9. The dialyzer of claim 7 , wherein the second end cap includes a port along the outgoing fluid flow path for administering medicaments or extracting a sample of the fluid.

10. The dialyzer of claim 1 , further comprising one or more magnets attached to the pump impeller, wherein the pump impeller is magnetically levitated during operation.

11. A blood treatment machine comprising:
a treatment module including a structure for releasably coupling with a dialyzer, the treatment module including a drive unit configured to generate dynamic magnetic fields to levitate and rotate a magnetic pump rotor within the dialyzer while the dialyzer is coupled with the treatment module,
wherein the treatment module further comprises a first pair of conduits configured to: (i) extend to fluidly couple with a first substituate liquid port and a first dialysate port defined by the dialyzer, and (ii) retract to uncouple from the first substituate liquid port and the first dialysate port.

12. The blood treatment machine of claim 11 , further comprising a blood treatment machine console that controls the treatment module, wherein the treatment module is mounted to an arm extending from the blood treatment machine console.

13. The blood treatment machine of claim 11 , wherein the treatment module further comprises a second pair of conduits configured to: (i) extend to fluidly couple with a second substituate liquid port and a second dialysate port defined by the dialyzer, and (ii) retract to uncouple from the second substituate liquid port and the second dialysate port.

14. The dialyzer of claim 1 , wherein the pump impeller comprises:
a first end portion to which one or more magnets are attached; and
a second end portion opposite of the first end portion and comprising a plurality of impeller blades.

15. The dialyzer of claim 14 , wherein the first end portion is diametrically smaller than the second end portion.

16. The dialyzer of claim 14 , wherein the pump impeller defines a central lumen that is open and that extends through an entire length of the impeller along the longitudinal axis of the housing.

17. The dialyzer of claim 16 , wherein liquid to be pumped enters the central lumen of the pump impeller through a central aperture at the second end portion of the of the pump impeller.

18. The dialyzer of claim 14 , wherein the housing comprises an annular concave wall surface around the second end portion of the pump impeller.

19. The dialyzer of claim 18 , wherein the annular concave wall surface defines a toroidal space around the pump impeller.

20. The blood treatment machine of claim 11 , wherein the first pair of conduits are configured to: (i) automatically extend to fluidly couple with the first substituate liquid port and the first dialysate port defined by the dialyzer, and (ii) automatically retract to uncouple from the first substituate liquid port and the first dialysate port.

Assignees

• Fresenius Medical Care Deutschland Gmbh

Inventors

• Heide Alexander
• Nikolic Dejan
• Peters Arne
• Wiktor Christoph

Classifications

• B01D61/243

  Dialysis · CPC title

• B01D63/034

  Lumen open in more than two directions · CPC title

• A61M1/267 Primary

  used for pumping · CPC title

• A61M39/24

  Check- or non-return valves · CPC title

• B01D63/02

  Hollow fibre modules · CPC title