Magnesium single crystal for biomedical applications and methods of making same

Patent metadata

Field	Value
Publication number	US-11730857-B2
Application number	US-202117195997-A
Country	US
Kind code	B2
Filing date	Mar 9, 2021
Priority date	Aug 18, 2014
Publication date	Aug 22, 2023
Grant date	Aug 22, 2023

Abstract

A biomedical implant ( 16, 18 ) is formed from magnesium (Mg) single crystal ( 10 ). The biomedical implant ( 16, 18 ) may be biodegradable. The biomedical implant ( 16, 18 ) may be post treated to control the mechanical properties and/or corrosion rate thereof said Mg single crystal ( 10 ) without changing the chemical composition thereof. A method of making a Mg single crystal ( 10 ) for biomedical applications includes filling a single crucible ( 12 ) with more than one chamber with polycrystalline Mg, melting at least a portion of said polycrystalline Mg, and forming more than one Mg single crystal ( 10 ) using directional solidification.

First claim

What is claimed is:

1. A method of making a Mg single crystal for biomedical applications comprising:
filling a single crucible including more than one chamber with polycrystalline Mg;
melting at least a portion of said polycrystalline Mg;
forming more than one Mg single crystal using directional solidification; and
applying an annealing procedure in argon at a temperature maintained below the magnesium melting point for 1 to 50 hrs, thereby eliminating segregation of said Mg alloy during growth of said Mg single crystal.

2. The method of claim 1 , wherein said polycrystalline Mg is a polycrystalline Mg alloy.

3. The method of claim 2 , wherein the magnesium alloy contains rare earth elements.

4. The method according to claims 1 , 2 , or 3 , wherein the controlled crystallization of said Mg crystallization is caused by directional solidification from the Mg melt utilizing at least one method chosen from the Czochralski method, the Bridgman method, and the floating zone method.

5. The method of claim 1 , further comprising linear motion of the crucible of 0.5 mm/hr to 5 mm/hr and a crucible rotation rate of 0-15 rpm.

6. The method of claim 1 , further comprising use of a single crystal of zirconium or magnesium as a seed crystal.

7. The method of claim 1 , wherein the Mg single crystal is grown from a melt exposed to a soaking time of 1-50 hr and a constant soaking temperature of 10-150° C. above the melting point of magnesium.

8. The method of claim 7 , wherein the Mg single crystal is grown from a melt exposed to a soaking time of 30 hr and a constant soaking temperature of 75° C. above the melting point of magnesium.

9. The method of claim 1 , wherein the length to diameter ratio of the single crystals is in a range chosen from 7.5:1, 8.125:1, and 10:1.

10. The method of claim 1 , wherein the annealing temperature is 645° C. and the annealing procedure is applied for 14 hrs.

11. A method of making a Mg single crystal for biomedical applications comprising:
filling a split mold crucible locked with a carbon nanotube (CNT) thread or a CNT sheet with polycrystalline Mg;
melting at least a portion of said polycrystalline Mg; and
forming Mg single crystal using directional solidification.

Assignees

• Univ Cincinnati

Inventors

• Shanov Vesselin N
• Chaswal Vibhor
• Salunke Pravahan
• Joshi Madhura
• Zhang Guangqi
• Schulz Mark J
• Yarmolenko Sergey N
• Nienaber Doug

Classifications

• A61L27/047 Primary

  Other specific metals or alloys not covered by A61L27/042 - A61L27/045 or A61L27/06 · CPC title

• A61B17/80

  Cortical plates {, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates} · CPC title

• A61B17/86

  Pins or screws {or threaded wires; nuts therefor (A61B17/72 take precedence)} · CPC title

• A61F2/3099

  for temporo-mandibular [TM, TMJ] joints (endoprostheses for mandibular reconstruction A61F2/2803) · CPC title

• A61L27/58

  Materials at least partially resorbable by the body · CPC title