Mechanically resonant pulse relief valve and methods of use for assisted clearing of plugged aspiration

Patent metadata

Field	Value
Publication number	US-11730498-B2
Application number	US-202017133684-A
Country	US
Kind code	B2
Filing date	Dec 24, 2020
Priority date	Jan 23, 2020
Publication date	Aug 22, 2023
Grant date	Aug 22, 2023

Abstract

An aspiration system comprises an aspiration catheter, an aspiration source fluidly coupled to the aspiration catheter to create an aspiration flow path between the aspiration catheter and the aspiration source, a pressurized fluid source, and a passive pressure oscillation assembly fluidly coupled between the pressurized fluid source and the aspiration flow path. The passive pressure oscillation assembly is configured for being operated between a normal mode that prevents fluid communication between the pressurized fluid source and the aspiration flow path, and an oscillatory mode that pulses fluid communication between the pressurized fluid source and the aspiration flow path. The passive pressure oscillation assembly is configured for being triggered to switch from the normal mode to the oscillatory mode in response to a clog in the aspiration catheter.

First claim

What is claimed is:

1. A method of aspirating an occlusion from a patient, comprising:
creating an aspiration flow path between an aspiration catheter located adjacent the occlusion and an aspiration source;
preventing fluid communication between a pressurized fluid source and the aspiration flow path; and
pressure pulsing fluid between the pressurized fluid source and the aspiration flow path automatically, via a passive pressure oscillation assembly that is without user input and without an electronic sensor, in response to a clog in the aspiration catheter.

2. The method of claim 1 , wherein pressure pulsing fluid between the pressurized fluid source and the aspiration flow path causes pressure pulses to propagate in the aspiration flow path.

3. The method of claim 1 , wherein pressure pulsing fluid between the pressurized fluid source and the aspiration flow path causes fluid backflows to propagate in the aspiration flow path.

4. The method of claim 1 , wherein the pressurized fluid source comprises one of ambient air and a reservoir containing a liquid.

5. The method of claim 1 , further comprising ceasing pressure pulsing of the fluid between the pressurized fluid source and the aspiration flow path automatically in response to removal of the clog in the aspiration catheter.

6. The method of claim 1 , wherein fluid between the pressurized fluid source and the aspiration flow path is simultaneously pulsed at two different frequencies.

7. The method of claim 1 , wherein pressure pulsing fluid between the pressurized fluid source and the aspiration flow path automatically in response to a clog in the aspiration catheter comprises interrupting the aspiration flow path, such that the pulsing fluid between the pressurized fluid source and the aspiration flow path is directed towards the aspiration catheter.

8. The method of claim 1 , wherein pressure pulsing fluid between the pressurized fluid source and the aspiration flow path is automatically pulsed in accordance with an oscillatory mode that is triggered in response to the clog in the aspiration catheter.

9. The method of claim 1 , wherein the occlusion is a thrombus located in a blood vessel of the patient.

10. The method of claim 1 , wherein a manifold is in fluid communication between the pressurized fluid source and the aspiration flow path and comprises the passive pressure oscillation assembly.

11. A method of aspirating an occlusion from a patient, comprising:
creating an aspiration flow path between an aspiration catheter located adjacent the occlusion and an aspiration source;
preventing fluid communication between a pressurized fluid source and the aspiration flow path; and
pressure pulsing fluid between the pressurized fluid source and the aspiration flow path automatically, via a passive pressure oscillation assembly that is without user input and without an electronic sensor, in response to a drop in absolute pressure in the aspiration flow path that creates a negative activation pressure differential between the pressurized fluid source and the aspiration flow path equal to or less than −55 kPa.

12. The method of claim 11 , wherein pressure pulsing fluid between the pressurized fluid source and the aspiration flow path causes pressure pulses to propagate in the aspiration flow path.

13. The method of claim 11 , wherein pressure pulsing fluid between the pressurized fluid source and the aspiration flow path causes fluid backflows to propagate in the aspiration flow path.

14. The method of claim 11 , wherein the pressurized fluid source comprises one of ambient air and a reservoir containing a liquid.

15. The method of claim 11 , wherein the negative activation pressure differential is in the range of −55 kPa to −95 kPa.

16. The method of claim 11 , further comprising ceasing pressure pulsing fluid between the pressurized fluid source and the aspiration flow path automatically in response to a rise in absolute pressure in the aspiration flow path that creates a negative cessation pressure differential between the pressurized fluid source and the aspiration flow path greater than the negative activation pressure differential.

17. The method of claim 16 , wherein the negative cessation pressure differential is 10 kPa-25 kPa greater than the negative activation pressure differential.

18. The method of claim 11 , wherein pressure pulsing fluid between the pressurized fluid source and the aspiration flow path is simultaneously pulsed at two different frequencies.

19. The method of claim 11 , wherein fluid between the pressurized fluid source and the aspiration flow path is automatically pressure pulsed in accordance with an oscillatory mode of the passive pressure oscillation assembly that is triggered in response to the drop in absolute pressure in the aspiration flow path that creates the negative activation pressure differential between the pressurized fluid source and the aspiration flow path equal to or less than −55 kPa.

20. The method of claim 19 , wherein the occlusion is a thrombus located in a blood vessel of the patient.

21. The method of claim 11 , wherein a manifold is in fluid communication between the pressurized fluid source and the aspiration flow path and comprises the passive pressure oscillation assembly.

Assignees

• Stryker Corp
• Stryker European Operations Ltd

Inventors

• Porter Stephen

Classifications

• A61M1/83

  Tube strippers, i.e. for clearing the contents of the tubes · CPC title

• A61B17/22 Primary

  Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for · CPC title

• A61B2017/22079

  with suction of debris · CPC title

• A61M1/804

  using Laval or Venturi jet pumps · CPC title

• A61M1/81

  Piston pumps, e.g. syringes · CPC title