Devices, systems, and methods for the treatment of vascular defects

Patent metadata

Field	Value
Publication number	US-11730485-B2
Application number	US-201916718169-A
Country	US
Kind code	B2
Filing date	Dec 17, 2019
Priority date	Dec 17, 2018
Publication date	Aug 22, 2023
Grant date	Aug 22, 2023

Abstract

Devices, systems, and methods for treating vascular defects are disclosed herein. One aspect of the present technology, for example, includes an occlusive device comprising a mesh having a low-profile state for intravascular delivery to the aneurysm and a deployed state, the mesh comprising a first end portion, a second end portion, and a length extending between the first and second end portions, and a first lateral edge, a second lateral edge, and a width extending between the first and second lateral edges. The mesh may have a predetermined shape in the deployed state in which (a) the mesh is curved along its width, (b) the mesh is curved along its length, and (c) the mesh has an undulating contour across at least a portion of one or both of its length or its width. The mesh is configured to be positioned within the aneurysm in the deployed state such that the mesh extends over the neck of the aneurysm.

First claim

We claim:

1. An occlusive device for treating an aneurysm, wherein a neck of the aneurysm opens to a blood vessel, the device comprising:
a mesh having a low-profile state for intravascular delivery to the aneurysm and a deployed state, the mesh comprising—
a first end portion, a second end portion, and a length extending between the first and second end portions, and
a first lateral edge, a second lateral edge, and a width extending between the first and second lateral edges,
wherein the mesh has a predetermined shape in an expanded, unconstrained state in which (a) the mesh is curved along its width, (b) the mesh is curved along its length, and (c) the mesh has a plurality of undulations across at least a portion of one or both of its length or its width, and
wherein the mesh is configured to be positioned within the aneurysm in a deployed state such that the mesh extends over the neck of the aneurysm with at least one of the undulations being convex towards the blood vessel and at least a different one of the undulations being concave towards the blood vessel.

2. The occlusive device of claim 1 , wherein the mesh has a first side, a second side opposite the first side, and a thickness measured therebetween, and wherein the mesh has a generally constant thickness along its length.

3. The occlusive device of claim 1 , wherein the mesh does not define an inner cavity.

4. The occlusive device of claim 1 , wherein the mesh is formed of a tubular braid that has been flattened along it longitudinal axis such that opposing portions of a sidewall of the tubular braid are urged towards one another.

5. The occlusive device of claim 1 , wherein each of the plurality of undulations extend across at least a portion of the width of the mesh.

6. The occlusive device of claim 1 , wherein the mesh has a first side and a second side opposite the first side, and wherein the plurality of undulations comprise a first inflection region comprising a first peak at the first side and a first valley at the second side, a second inflection region comprising a second valley at the first side and a second peak at the second side, and a third inflection region comprising a third peak at the first side and a third valley at the second side, and wherein the mesh is configured to be positioned within an aneurysm such that the first side faces the aneurysm cavity and the second side faces the parent vessel.

7. The occlusive device of claim 1 , wherein the mesh comprises a divot extending across at least a portion of the length of the mesh.

8. The occlusive device of claim 7 , wherein the divot corresponds to a protrusion along the length of the mesh, and wherein the occlusive device is configured to be positioned within the aneurysm such that the protrusion is convex towards the aneurysm cavity.

9. The occlusive device of claim 1 , wherein the width of the mesh tapers in the direction of the first end portion.

10. The occlusive device of claim 1 , wherein the width of the mesh tapers in the direction of the second end portion.

11. The occlusive device of claim 1 , wherein the mesh is formed of a plurality of filaments, and wherein at least some of the filaments are drawn-filled tube (“DFT”) wires.

12. The occlusive device of claim 1 , wherein a proximal end of the mesh is configured to be detachably coupled to an elongated delivery member.

13. The occlusive device of claim 1 , wherein a proximal end of the occlusive device is configured to be detachably coupled to an elongated delivery member.

14. The occlusive device of claim 1 , further comprising an embolic element coupled to a proximal end of the mesh.

15. The occlusive device of claim 1 , further comprising a lead-in member coupled to a distal end of the mesh.

16. The occlusive device of claim 1 , wherein a radius of curvature of the mesh increases distally along its longitudinal axis between its proximal and distal ends.

17. The occlusive device of claim 1 , wherein a radius of curvature of the mesh decreases distally along its longitudinal axis between its proximal and distal ends.

18. An occlusive device for treating an aneurysm, wherein a neck of the aneurysm opens to a blood vessel, the device comprising:
a mesh having a low-profile state for intravascular delivery to the aneurysm and a deployed state, the mesh comprising—
a first end portion, a second end portion, and a length extending between the first and second end portions, and
a first lateral edge, a second lateral edge, and a width extending between the first and second lateral edges; and
a coil,
wherein the mesh has a predetermined shape in an expanded, unconstrained state in which (a) the mesh is curved along its width, (b) the mesh is curved along its length, and (c) the mesh has a plurality of longitudinally extending undulations, the undulations comprising first and second peaks separated by a valley, and
wherein the occlusive device is configured to be positioned within the aneurysm such that the mesh extends over the neck of the aneurysm with the first and second peaks convex toward the blood vessel and the valley concave towards the blood vessel and the coil is positioned between the dome of the aneurysm and the mesh.

19. The occlusive device of claim 18 , wherein the mesh and the coil are coupled end-to-end.

20. The occlusive device of claim 18 , wherein the mesh and the coil are coupled end-to-end and, when positioned within a delivery catheter for intravascular delivery to the aneurysm, the mesh is distal of the coil such that the mesh is delivered to the aneurysm before the coil.

21. An occlusive device for treating an aneurysm, wherein a neck of the aneurysm opens to a blood vessel, the device comprising:
a mesh having a low-profile state for intravascular delivery to the aneurysm and a deployed state, the mesh comprising—
a first end portion, a second end portion, and a length extending between the first and second end portions, and
a first lateral edge, a second lateral edge, and a width extending between the first and second lateral edges,
wherein the mesh has a predetermined shape in an expanded, unconstrained state in which the mesh is curved along its width and along its length, and has a plurality of laterally extending undulations, the undulations comprising first and second peaks separated by a valley between the first and second lateral edges, and
wherein the mesh is configured to be positioned within the aneurysm in a deployed state such that the mesh extends over the neck of the aneurysm with the first and second peaks convex toward the blood vessel and the valley concave towards the blood vessel.

Assignees

• Covidien Lp

Inventors

• Hamel Gregory
• Quinn Patrick
• Rosqueta Arturo
• Sosnowski Stephen
• Andrews Christopher
• Dang Hieu
• Nguyen Dinh
• Pecor Robert
• Dinh Minh Q
• Tatavoosian Ahramahzd

Classifications

• A61B17/12113 Primary

  within an aneurysm · CPC title

• A61B17/00234

  for minimally invasive surgery (A61B17/0218, A61B17/0469, A61B17/12013, A61B17/1285, A61B17/29, A61B17/320016 take precedence) · CPC title

• A61B17/1214

  Coils or wires · CPC title

• A61B17/12145

  having a pre-set deployed three-dimensional shape (methods of manufacturing A61B2017/00526) · CPC title

• A61B17/12172

  having a pre-set deployed three-dimensional shape (methods of manufacturing A61B2017/00526) · CPC title