Sensing element and wireless communication device for single-use elements

Patent metadata

Field	Value
Publication number	US-11729536-B2
Application number	US-201916967338-A
Country	US
Kind code	B2
Filing date	Jan 21, 2019
Priority date	Feb 5, 2018
Publication date	Aug 15, 2023
Grant date	Aug 15, 2023

Abstract

Summarizing the invention, a sensing element for monitoring the state of a single-use sterilizable element such as a single-use bioreactor, wherein the state of the single-use sterilizable element is determined by at least one environmental condition is provided. The sensing element comprises: a variable component having at least one physical property that is configured to change in response to the at least one environmental condition and/or a change thereof, wherein the variable component comprises a sensing material with changing absorption characteristics for electromagnetic radiation configured to change in response to the at least one environmental condition and/or a change thereof.

First claim

The invention claimed is:

1. A communication device comprising:
a sensing element for monitoring a state of a single-use sterilizable element, wherein the state of the single-use sterilizable element is determined by at least one environmental condition, the sensing element comprising a variable component having at least one physical property that is configured to change in response to the at least one environmental condition and/or a change thereof, wherein the variable component comprises a sensing material with changing absorption characteristics for electromagnetic radiation configured to change in response to the at least one environmental condition and/or the change thereof;
an electronic circuit;
an antenna connected to the electronic circuit, the antenna being configured to transmit a radio-frequency signal modulated by the electronic circuit;
coupling means configured to operatively couple the electronic circuit to the sensing element;
wherein:
the electronic circuit is operatively coupled to the sensing element so that the at least one physical property affects a modulation of the modulated radio-frequency signal,
the coupling means comprises a LED, a first photodiode, wiring and electrical components,
the LED and the first photodiode are disposed such that the sensing material is between the LED and the first photodiode, and
the LED is configured to emit light towards the sensing material to be transmitted by the sensing material, such that the light that is transmitted by the sensing material is incident on the first photodiode.

2. The communication device according to claim 1 , wherein the sensing material has changing absorption characteristics for electromagnetic radiation in a first range of wavelength, and the sensing material has substantially fixed absorption characteristics for electromagnetic radiation in a second range of wavelength.

3. The communication device according to claim 2 , wherein the sensing material is substantially non-absorbent in the second range of wavelength.

4. The communication device according to claim 1 , wherein the sensing material has first changing absorption characteristics for electromagnetic radiation in a first range of wavelength and second changing absorption characteristics for electromagnetic radiation in a second range of wavelength being different from the first range of wavelength.

5. The communication device according to 1 , wherein the at least one physical property is configured to change gradually and irreversibly.

6. The communication device of claim 1 , further comprising a second photodiode and a comparator, wherein:
the first photodiode is sensitive to a first range of wavelength and the second photodiode is sensitive to a second range of wavelength,
the second photodiode is disposed such that the sensing material is between the LED and the second photodiode,
the LED is configured to emit light towards the sensing material such that the light that is transmitted by the sensing material is incident on the second photodiode, and
the comparator is configured to compare a first current generated by the first photodiode in response to the light incident on the first photodiode to a second current generated by the second photodiode in response to the light incident on the second photodiode and to output a third current proportional to a difference between the first current and the second current.

7. A method for determining a state of a single-use sterilizable element comprising a sensing element, wherein the state of the single-use sterilizable element is determined by at least one environmental condition and the sensing element comprises a variable component having at least one physical property that is configured to change in response to the at least one environmental condition and/or a change thereof, wherein the variable component comprises a sensing material with changing absorption characteristics for electromagnetic radiation configured to change in response to the at least one environmental condition and/or the change thereof, the method comprising:
providing an electronic circuit and an antenna connected to the electronic circuit that transmits a radio-frequency signal modulated by the electronic circuit;
operatively coupling the electronic circuit to the sensing element so that the at least one physical property affects a modulation of the modulated radio-frequency signal; and
sending an interrogating signal to the antenna to prompt the antenna to transmit the modulated radio-frequency signal based on the affected modulation,
wherein operatively coupling the electronic circuit to the sensing element comprises connecting coupling means to the electronic circuit, and
wherein:
the coupling means comprise a LED, a first photodiode, wiring and electrical components,
the LED and the first photodiode are disposed such that the sensing material is between the LED and the first photodiode, and
the LED is configured to emit light towards the sensing material to be transmitted by the sensing material, such that the light that is transmitted by the sensing material is incident on the first photodiode.

Assignees

• Sartorius Stedim Biotech Gmbh

Inventors

• Grimm Christian
• Scholz Jochen
• Bode Matthias
• Prediger Andreas
• Courtney Patrick

Classifications

• H04Q9/00 Primary

  Arrangements in telecontrol or telemetry systems for selectively calling a substation from a main station, in which substation desired apparatus is selected for applying a control signal thereto or for obtaining measured values therefrom · CPC title

• H05K1/0274

  Optical details, e.g. printed circuits comprising integral optical means (H05K1/0269 takes precedence; coupling light guides with opto-electronic components G02B6/42) · CPC title

• H05K2201/10106

  Light emitting diode [LED] · CPC title