(Cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles

US11725004B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-11725004-B2
Application numberUS-202117398155-A
CountryUS
Kind codeB2
Filing dateAug 10, 2021
Priority dateMay 17, 2013
Publication dateAug 15, 2023
Grant dateAug 15, 2023

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

    Technology tags used to group this patent with similar filings.

  7. Citations and related patents

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Abstract

Official abstract text for this publication.

This invention relates to novel (Cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles and their use as CB2 cannabinoid receptor agonists, pharmaceutical compositions containing the same, and their use for the treatment of CB2 receptor mediated disorders or conditions.

First claim

Opening claim text (preview).

The invention claimed is: 1. A method of treating diabetic neuropathy, comprising administering to a human being an effective amount of a compound selected from the group consisting of and a pharmaceutically acceptable salt thereof, to treat the diabetic neuropathy. 2. The method of claim 1 , wherein the compound is 3. The method of claim 1 , wherein the compound is administered in the form of a tablet, pill, or capsule. 4. The method of claim 2 , wherein the compound is administered in the form of a tablet, pill, or capsule. 5. A method of treating neuropathic pain due to diabetic peripheral neuropathy, comprising administering to a human being an effective amount of a compound selected from the group consisting of and a pharmaceutically acceptable salt thereof, to treat the neuropathic pain due to diabetic peripheral neuropathy. 6. The method of claim 5 , wherein the compound is 7. The method of claim 5 , wherein the compound is administered in the form of a tablet, pill, or capsule. 8. The method of claim 6 , wherein the compound is administered in the form of a tablet, pill, or capsule. 9. A method of treating neuropathic pain due to diabetic neuropathy, comprising administering to a human being an effective amount of a compound selected from the group consisting of and a pharmaceutically acceptable salt thereof, to treat the neuropathic pain due to diabetic neuropathy. 10. The method of claim 9 , wherein the compound is 11. The method of claim 9 , wherein the compound is administered in the form of a tablet, pill, or capsule. 12. The method of claim 10 , wherein the compound is administered in the form of a tablet, pill, or capsule. 13. A method of treating nerve injury-induced neuropathic pain, comprising administering to a human being an effective amount of a compound selected from the group consisting of and a pharmaceutically acceptable salt thereof, to treat the nerve injury-induced neuropathic pain. 14. The method of claim 13 , wherein the compound is 15. The method of claim 13 , wherein the compound is administered in the form of a tablet, pill, or capsule. 16. The method of claim 14 , wherein the compound is administered in the form of a tablet, pill, or capsule.

Assignees

Inventors

Classifications

  • C07D417/12Primary

    linked by a chain containing hetero atoms as chain links · CPC title

  • not condensed and containing further heterocyclic rings · CPC title

  • having one double bond between ring members or between a ring member and a non-ring member · CPC title

  • Nitrogen atoms · CPC title

  • containing two hetero rings · CPC title

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Frequently asked questions

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What does patent US11725004B2 cover?
This invention relates to novel (Cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles and their use as CB2 cannabinoid receptor agonists, pharmaceutical compositions containing the same, and their use for the treatment of CB2 receptor mediated disorders or conditions.
Who is the assignee on this patent?
Centrexion Therapeutics Corp
What technology area does this patent fall under?
Primary CPC classification C07D417/12. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Aug 15 2023 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 6 related publications on this page (citations in our corpus or others sharing the same primary CPC).