Filamentary devices for treatment of vascular defects

Patent metadata

Field	Value
Publication number	US-11723667-B2
Application number	US-202017028037-A
Country	US
Kind code	B2
Filing date	Sep 22, 2020
Priority date	Aug 16, 2013
Publication date	Aug 15, 2023
Grant date	Aug 15, 2023

Abstract

Devices and methods for treatment of a patient's vasculature may include a resilient self-expanding permeable implant having a radially constrained elongated state configured for delivery within a catheter lumen and an expanded state with a longitudinally shortened configuration, and a plurality of elongate filaments which are woven together. Each of the plurality of elongate filaments may have a diameter between about 0.0005 and about 0.005 inches. The implant includes at least some filaments consisting of nitinol and at least some composite filaments that are drawn filled tube wires comprising an external nitinol tube and a highly radiopaque material concentrically disposed within the external tube. The implant has at least about 40% composite filaments relative to a total number of filaments, and wherein a total number of filaments is about 10 to about 300.

First claim

What is claimed is:

1. A device for treatment of a patient's vasculature, comprising:
a resilient self-expanding permeable implant including a radially constrained elongated state configured for delivery within a catheter lumen, an expanded state with a longitudinally shortened configuration relative to the radially constrained state, and a plurality of elongate filaments which are woven together, wherein each of the plurality of elongate filaments has a diameter between about 0.0005 inches to about 0.005 inches, the permeable implant comprising at least some filaments consisting of nitinol and at least some composite filaments, the composite filaments comprising drawn filled tube wires comprising an external nitinol tube and a highly radiopaque material concentrically disposed within the external tube, and wherein the permeable implant has at least about 40% composite filaments relative to a total number of filaments, and wherein a total number of filaments is about 10 to about 300; and
a tether coupled to a proximal end of the permeable implant.

2. The device of claim 1 , wherein the drawn filled tube wires have a fill ratio of cross sectional area selected from the group consisting of between about 10% and about 50%, between about 20% and about 40%, and between about 25% and about 35%.

3. The device of claim 1 , wherein the highly radiopaque material of the composite filaments comprises a material selected from the group consisting of tantalum, platinum, and gold.

4. The device of claim 1 , wherein each of the composite filaments has a diameter selected from the group consisting of 0.00075″, 0.001″, 0.0015″, and 0.00125″.

5. The device of claim 1 , wherein the expanded state has a globular configuration.

6. The device of claim 1 , wherein the implant is a stent.

7. The device of claim 1 , wherein the plurality of elongate filaments are secured relative to each other at a proximal end of the permeable implant.

8. The device of claim 1 , wherein the total number of filaments is selected from the group consisting of about 70 to about 300, about 10 to about 100, about 60 to about 80, about 100 to about 200, and about 80 to about 180.

9. The device of claim 1 , wherein each of the plurality of elongate filaments has a diameter selected from the group consisting of between about 0.0008 inches to about 0.004 inches, between about 0.001 inches to about 0.003 inches, and between about 0.0004 inches to about 0.002 inches.

10. The device of claim 1 , wherein the tether is configured to be releasably coupled to a delivery apparatus.

11. A method for treating a patient's vasculature, comprising the steps of:
advancing a resilient self-expanding permeable implant coupled to a pusher within a catheter to a region of interest within the patient's vasculature,
wherein the permeable implant comprises a plurality of elongate filaments that are woven together and a tether, wherein the permeable implant is in a radially constrained elongated state within the catheter, wherein each of the plurality of elongate filaments has a diameter between about 0.0005 inches to about 0.005 inches, wherein the permeable implant comprises at least some filaments consisting of nitinol and at least some composite filaments, the composite filaments comprising drawn filled tube wires comprising an external nitinol tube and a highly radiopaque material concentrically disposed within the external tube, and wherein the permeable implant has at least about 40% composite filaments relative to a total number of filaments, wherein a total number of filaments is about 10 to about 300, and wherein the tether is coupled to a proximal end of the permeable implant and a distal end of the pusher;
deploying the permeable implant in the region of interest, wherein the permeable implant expands to an expanded state with a longitudinally shortened configuration relative to the radially constrained state within the region of interest; and

detaching the permeable implant from the pusher.

12. The method of claim 11 , further comprising the step of withdrawing the catheter from the region of interest after detaching the permeable implant, wherein the permeable implant is in the expanded state after the permeable implant is detached from the pusher.

13. The method of claim 11 , wherein the drawn filled tube wires have a fill ratio of cross sectional area selected from the group consisting of between about 10% and about 50%, between about 20% and about 40%, and between about 25% and about 35%.

14. The method of claim 11 , wherein the highly radiopaque material of the composite filaments comprises a material selected from the group consisting of tantalum, platinum, and gold.

15. The method of claim 11 , wherein each of the composite filaments has a diameter selected from the group consisting of 0.00075″, 0.001″, 0.0015″, and 0.00125″.

16. The method of claim 11 , wherein the expanded state has a globular configuration.

17. The method of claim 11 , wherein the implant is a stent.

18. The method of claim 11 , wherein the plurality of elongate filaments are secured relative to each other at a proximal end of the permeable implant.

19. The method of claim 11 , wherein the region of interest is a cerebral aneurysm.

20. The method of claim 11 , wherein the region of interest is a vessel.

21. The method of claim 11 , wherein the total number of filaments is selected from the group consisting of about 70 to about 300, about 10 to about 100, about 60 to about 80, about 100 to about 200, and about 80 to about 180.

22. The method of claim 11 , wherein each of the plurality of elongate filaments has a diameter selected from the group consisting of between about 0.0008 inches to about 0.004 inches, between about 0.001 inches to about 0.003 inches, and between about 0.0004 inches to about 0.002 inches.

Assignees

• Microvention Inc

Inventors

• Hewitt Todd
• Merritt Brian E
• Patterson William R

Classifications

• A61B17/12113 Primary

  within an aneurysm · CPC title

• A61B17/12013

  for use in minimally invasive surgery, e.g. endoscopic surgery · CPC title

• A61B17/12031

  complete occlusion · CPC title

• A61B17/12118

  for positioning in conjunction with a stent · CPC title

• A61B17/12172

  having a pre-set deployed three-dimensional shape (methods of manufacturing A61B2017/00526) · CPC title