Organic electroluminescent materials and devices
US-2021070792-A1 · Mar 11, 2021 · US
US11718617B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11718617-B2 |
| Application number | US-202218072497-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 30, 2022 |
| Priority date | May 4, 2020 |
| Publication date | Aug 8, 2023 |
| Grant date | Aug 8, 2023 |
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The present disclosure provides compounds of Formula I, useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 (“TREM2”).This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.
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What is claimed is: 1. A compound selected from: Ex. 3 Ex. 19 Ex. 22 Ex 23 Ex. 28 Ex. 49 Ex. 61 Ex. 77 Ex. 82 Ex. 94 Ex. 107 Ex. 117 Ex. 123 Ex. 124 Ex. 125 Ex. 126 Ex. 128 Ex. 129 Ex. 131 Ex. 133 Ex. 136 Ex. 137 Ex. 146 Ex. 149 Ex. 150 Ex. 151
Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00 · CPC title
not condensed and containing further heterocyclic rings, e.g. timolol · CPC title
ortho- or peri-condensed with heterocyclic rings · CPC title
Ortho-condensed systems · CPC title
containing three or more hetero rings · CPC title
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