Process for preparing aminopyrimidine derivatives
US-11286253-B2 · Mar 29, 2022 · US
US11708362B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11708362-B2 |
| Application number | US-202217704718-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 25, 2022 |
| Priority date | Jul 28, 2017 |
| Publication date | Jul 25, 2023 |
| Grant date | Jul 25, 2023 |
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The present invention provides an improved process for preparing an aminopyrimidine derivative or pharmaceutically acceptable salt thereof having a selective inhibitory activity against protein kinases, especially against the protein kinases for mutant epidermal growth factor receptors. Additional, the present invention provides novel intermediates useful for said process and processes for preparing the same.
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What is claimed is: 1. A compound of Formula II: or a salt thereof.
containing three or more hetero rings · CPC title
not condensed and containing further heterocyclic rings · CPC title
not condensed and containing further heterocyclic rings, e.g. timolol · CPC title
Compounds with one or more Sn-N linkages · CPC title
directly linked by a ring-member-to-ring-member bond · CPC title
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