System, methodologies and components for skin sculpting with magnetic particles

Patent metadata

Field	Value
Publication number	US-11701522-B2
Application number	US-202016785034-A
Country	US
Kind code	B2
Filing date	Feb 7, 2020
Priority date	Feb 7, 2019
Publication date	Jul 18, 2023
Grant date	Jul 18, 2023

Abstract

A method, apparatus and components thereof enable stimulating synthesis of new collagen and elastic fibers in superficial tissues, of a human or other living subject by introducing magnetic particles into the superficial tissue and activating the magnetic particles by application of magnetic field to stimulate synthesis of new collagen and elastic fibers.

First claim

The invention claimed is:

1. A system for affecting superficial tissue in a live subject, the system comprising:
a plurality of magnetic particles configured to be injected into the superficial tissue, wherein at least one magnetic particle of the plurality of magnetic particles includes a tether to facilitate removal of the particle from the superficial tissue;
a power source configured to provide electrical power;
a magnetic field generator coupled to the power source to receive power to generate a magnetic field; and
a controller coupled to the power source and the magnetic field generator to control the power source and the magnetic field generator to produce the magnetic field in the proximity of the superficial tissue,
wherein the at least one part of at least one magnetic particle of a plurality of magnetic particles injected into the superficial tissue is activated by the magnetic field, and
wherein the controller is configured to affect superficial tissue by moving the at least one magnetic particle within the superficial tissue by application of the generated magnetic field to produce a desired cosmetic effect by disrupting collagen or elastic fibers in the superficial tissue via the movement.

2. The system of claim 1 , wherein the desired cosmetic effect is removal or reduction of an appearance of at least one wrinkle.

3. The system of claim 1 , further comprising a mechanism for injecting the plurality of magnetic particles into the superficial tissue.

4. The system of claim 3 , wherein the mechanism for injecting the plurality of magnetic particles into the superficial tissue is a syringe containing a solution including the plurality of magnetic particles.

5. The system of claim 3 , wherein the mechanism for injecting the plurality of magnetic particles into the superficial tissue applies magnetic fields, using rotation, to perform magnetic drilling.

6. The system of claim 3 , wherein the mechanism for injecting the plurality of magnetic particles into the superficial tissue uses temporary diamagnetic propulsive focusing of the plurality of magnetic particles by applying transient magnetic field pulses to the superficial tissue.

7. The system of claim 1 , wherein the power source, controller and magnetic field generator are incorporated in a one-sided magnetic resonance imaging system.

8. The system of claim 1 , further comprising an imaging system for imaging the at least one magnetic particle of the plurality of magnetic particles to monitor movement and/or activation of the at least one particle.

9. The system of claim 8 , wherein imaging of the at least one magnetic particle of the plurality of magnetic particles in tissue is used to avoid damage to important tissue structures.

10. The system of claim 1 , wherein the activation of the at least one part of the at least one magnetic particle of the plurality of magnetic particles are configured to rotate the at least one magnetic particle in the superficial tissue to disrupt tissue fibers.

11. The system of claim 1 , wherein the activation of the at least one part of the at least one magnetic particle of the plurality of magnetic particles are configured to heat the tissue via magnetic induction applied to the at least one magnetic particle in the superficial tissue to disrupt tissue fibers.

12. The system of claim 1 , wherein the activation of the at least one part of the at least one magnetic particle of the plurality of magnetic particles are configured to release a drug or other chemical agent loaded on or in the at least one magnetic particle in response to magnetic activation.

13. A method for affecting superficial tissue in a live subject to achieve a desired cosmetic effect, the method comprising:
generating a magnetic field using a power source coupled to a magnetic field generator under control of a controller to produce a magnetic field in proximity to the superficial tissue;
positioning a plurality of magnetic particles within the superficial tissue;
activating, by the magnetic field, at least one part of at least one magnetic particle of the plurality of magnetic particles in the superficial tissue;
moving the at least one magnetic particle within the superficial tissue by application of the generated magnetic field; and
disrupting collagen or elastic fibers in the superficial tissue via the movement to achieve the desired cosmetic effect.

14. The method of claim 13 , wherein the desired cosmetic effect is removal or reduction of an appearance of at least one wrinkle.

15. The method of claim 13 , wherein positioning the at least one magnetic particle of the plurality of magnetic particles within the superficial tissue comprises injecting the plurality of magnetic particles into the superficial tissue.

16. The method of claim 15 , wherein injecting the plurality of magnetic particles into the superficial tissue comprises using a syringe containing a solution including the plurality of magnetic particles.

17. The method of claim 15 , wherein injecting the plurality of magnetic particles into the superficial tissue comprises applying magnetic fields, using rotation, to perform magnetic drilling.

18. The method of claim 15 , wherein injecting the plurality of magnetic particles into the superficial tissue uses temporary diamagnetic propulsive focusing of the plurality of magnetic particles by applying transient magnetic field pulses to the superficial tissue.

19. The method of claim 13 , wherein the power source, controller and magnetic field generator are incorporated in a one-sided magnetic resonance imaging system.

20. The method of claim 13 , further comprising imaging the at least one magnetic particle of the plurality of magnetic particles to monitor movement and/or activation of the at least one magnetic particle.

21. The method of claim 20 , wherein imaging of the at least one magnetic particle of the plurality of magnetic particles in tissue is used to avoid damage to important tissue structures.

22. The method of claim 13 , wherein the activation of the at least one part of the at least one magnetic particle of the plurality of magnetic particles rotates the at least one magnetic particle in the superficial tissue to disrupt tissue fibers.

23. The method of claim 13 , wherein the activation of the at least one part of the at least one magnetic particle of the plurality of magnetic particles heats the tissue via magnetic induction applied to the at least one magnetic particle in the superficial tissue to disrupt tissue fibers.

24. The method of claim 13 , wherein the activation of the at least one part of the at least one magnetic particle of the plurality of magnetic particles releases a drug or other chemical agent loaded on or in the at least one magnetic particle in response to magnetic activation.

25. The method of claim 13 , wherein the at least one magnetic particle of the plurality of magnetic particles is tethered to facilitate removal of the at least one magnetic particle of the plurality of magnetic particles from the superficial tissue.

Assignees

• Weinberg Medical Physics Inc

Inventors

• Jafari Sahar
• Weinberg Irving

Classifications

• A61N2/004 Primary

  specially adapted for a specific therapy · CPC title

• A61M37/00 Primary

  Other apparatus for introducing media into the body (for reproduction or fertilisation A61B17/425; apparatus for iontophoresis or cataphoresis A61N1/30); Percutany, i.e. introducing medicines into the body by diffusion through the skin (salt baths A61H33/04) · CPC title

• G01R33/3808

  Magnet assemblies for single-sided MR wherein the magnet assembly is located on one side of a subject only; Magnet assemblies for inside-out MR, e.g. for MR in a borehole or in a blood vessel, or magnet assemblies for fringe-field MR · CPC title

• G01R33/1276

  of magnetic particles, e.g. imaging of magnetic nanoparticles (G01R33/1269 takes precedence) · CPC title

• A61B17/00234 Primary

  for minimally invasive surgery (A61B17/0218, A61B17/0469, A61B17/12013, A61B17/1285, A61B17/29, A61B17/320016 take precedence) · CPC title