Method for dosing liquid by means of a pipette and a syringe, and pipette for actuating a syringe for dosing liquid

Patent metadata

Field	Value
Publication number	US-11697113-B2
Application number	US-202016934243-A
Country	US
Kind code	B2
Filing date	Jul 21, 2020
Priority date	Dec 16, 2016
Publication date	Jul 11, 2023
Grant date	Jul 11, 2023

Abstract

A pipette with an adjustable dosing increment, wherein a control apparatus determines a dosing volume by a set dosing increment when a syringe is inserted in the pipette, and determines a maximum possible number of dosing steps following an execution of a reverse stroke without refilling the syringe given the set dosing increment and completely or partially filled syringe by the position of a displacement means on the path, and displays the maximum number of dosing steps on a display apparatus until the reverse stroke is executed. The control apparatus also determines the number of executed dosing steps and displays the number of executed dosing steps and/or the number of dosing steps still possible without refilling the syringe on the display apparatus.

First claim

The invention claimed is:

1. A pipette ( 1 ) for handling a syringe ( 3 ), comprising:
a rod-shaped housing ( 2 ),
a seat ( 20 ) having an opening ( 21 . 1 ) at a bottom end of the housing ( 2 ) for inserting a syringe ( 3 ) having a fastening section ( 16 ) at the a top edge of a cylinder ( 11 ),
a seat body ( 25 ) having a second seat ( 24 ) and another a second opening ( 21 . 2 ) at the bottom end in the housing ( 2 ) for receiving a second fastening section ( 19 ) of a plunger ( 12 ) of the syringe ( 3 ),
means for releasably holding the fastening section ( 16 ) in the seat ( 20 ) and the second fastening section ( 19 ) in the second seat ( 24 ), and
at least one means for displacing the seat body ( 25 ) within the housing ( 2 ) in a longitudinal direction of the housing ( 2 ),
the housing further having
a drawing lever ( 5 ) that can be actuated outside of the housing ( 2 ) for drawing liquid into the syringe ( 3 ),
a control button ( 8 ) that can be actuated outside of the housing ( 2 ) for the a stepwise discharging of liquid from the syringe ( 3 ),
an adjusting element for adjusting a dosing increment amount that can be adjusted outside of the housing ( 2 ),
means for detecting the dosing increment amount set with the adjusting element,
means for detecting the syringe ( 3 ) releasably connected to the pipette ( 1 ),
means for detecting a respective position of the at least one means for displacing the seat body ( 25 ) during displacement of the at least one means for displacing along a path relative to the housing ( 2 ),
an electronic control apparatus ( 42 ) connected to each of the means for detecting, and
an electronic display apparatus ( 9 ) connected to the electronic control apparatus ( 42 ),

wherein the control apparatus ( 42 ) is configured to determine a dosing volume determined by the set dosing increment amount when the syringe ( 3 ) is inserted in the pipette ( 1 ), and determine a maximum possible number of dosing steps following an execution of a reverse stroke without refilling the syringe ( 3 ) given the set dosing increment amount and the position of the at least one means for displacing on the path, and display the determined maximum possible number of dosing steps and the position of the at least one means for displacing on display apparatus ( 9 ), the control apparatus configured to determine an execution of a reverse stroke to be executed by the actuation of the control button ( 8 ), and indicates the determination of the execution of a reverse stroke to be executed on the display apparatus ( 9 ) until the reverse stroke is executed, and the control apparatus determines the number of executed dosing steps and displays the number of executed dosing steps determined on the display apparatus ( 9 ).

2. The pipette ( 1 ) according to claim 1 , wherein the means for detecting the respective position of the at least one means for displacing the seat body ( 25 ) has an incremental encoder arranged on the at least one means for displacing and at least one sensor ( 44 ) fixedly arranged in the housing ( 2 ) and connected to the control apparatus ( 42 ) for detecting the displacement of the incremental encoder.

3. The pipette ( 1 ) according to claim 2 , wherein the at least one means for displacing is a toothed rack ( 27 ) having a bottom end which is connected to the seat body ( 25 ) that can be engaged with a pawl ( 37 ) pivotably mounted on the control button ( 8 ) so that when the control button ( 8 ) is actuated to displace the toothed rack ( 27 ) a dosing step is completed.

4. The pipette ( 1 ) according to claim 2 , wherein the incremental encoder is integral with the toothed rack ( 27 ), or is a component securely connected to the toothed rack ( 27 ).

Assignees

• Eppendorf Ag

Inventors

• Reichmuth Burkhardt

Classifications

• B01L2300/027

  Digital display, e.g. LCD, LED · CPC title

• B01L2300/0627

  Sensor or part of a sensor is integrated · CPC title

• B01L2300/025

  Displaying results or values with integrated means · CPC title

• B01L3/0237

  Details of electronic control, e.g. relating to user interface · CPC title

• B01L3/0234

  Repeating pipettes, i.e. for dispensing multiple doses from a single charge · CPC title