Method and apparatus for transapical procedures on a mitral valve

Patent metadata

Field	Value
Publication number	US-11678872-B2
Application number	US-202016866382-A
Country	US
Kind code	B2
Filing date	May 4, 2020
Priority date	Jan 3, 2014
Publication date	Jun 20, 2023
Grant date	Jun 20, 2023

Abstract

Apparatus and methods for performing a non-invasive procedure to repair a cardiac valve are described herein. In some embodiments, apparatus and methods are described herein for repairing a mitral valve using an edge-to-edge repair to secure the mitral valve leaflets. Implant securing devices are also described that can be used during a procedure to repair a mitral valve. In some embodiments, an implant securing device includes an outer member and an inner member movably disposed within the outer member. The inner member can be used to hold or secure a suture extending from an implant deployed on an atrial side of a leaflet of a mitral valve, and the outer member can be used to push or move a half hitch knot toward a ventricular side of the leaflet, which can be used to secure the implant in the desired position.

First claim

What is claimed is:

1. A method of treating a heart valve, the method comprising:
deploying a first tissue anchor on an atrial side of a first leaflet of a heart valve of a heart;
deploying a second tissue anchor on an atrial side of a second leaflet of the heart valve;
on a ventricular side of the first and second leaflets, forming a knot by tying a first suture tail associated with the first tissue anchor to a second suture tail associated with the second tissue anchor;
pushing, using a pushing feature of a pushing device, the knot distally towards the heart valve to thereby pull the first tissue anchor and the second tissue anchor together, the pushing device comprising a shaft having a side window at a distal end portion of the shaft; and
prior to said forming the knot, drawing the first suture tail through the side window of the shaft of the pushing device.

2. The method of claim 1 , wherein the pushing feature comprises a distal frame portion of the side window.

3. The method of claim 1 , wherein said forming the knot is performed distal to a distal end of the pushing device.

4. The method of claim 1 , further comprising, while forming the knot, holding a third suture tail associated with the first tissue anchor and a fourth suture tail associated with the second tissue anchor with a suture-holding device.

5. The method of claim 4 , wherein:
the suture-holding device comprises a tube; and
the method further comprises drawing the third suture tail and the fourth suture tail through the tube.

6. The method of claim 5 , further comprising pressing a distal end of the suture-holding device against the ventricular side of the first and second leaflets while performing said forming the knot and pushing the knot.

7. The method of claim 1 , further comprising securing the first suture tail and the second suture tail to an apex region of the heart to thereby tether the first leaflet and the second leaflet to the apex region.

8. The method of claim 7 , wherein said securing comprises anchoring the first suture tail and the second suture tail to a pledget disposed on an outside surface of the apex region.

9. A method of treating a heart valve, the method comprising:
deploying a first tissue anchor on an atrial side of a first leaflet of a heart valve of a heart;
deploying a second tissue anchor on an atrial side of a second leaflet of the heart valve;
on a ventricular side of the heart valve, forming a first knot by tying a first suture tail associated with the first tissue anchor to a second suture tail associated with the second tissue anchor;
while forming the first knot, holding a third suture tail associated with the first tissue anchor and a fourth suture tail associated with the second tissue anchor with a suture-holding device; and
pushing, using a pushing device, the first knot distally towards the heart valve to thereby pull the first tissue anchor and the second tissue anchor together.

10. The method of claim 9 , wherein:
the suture-holding device comprises a tube; and
the method further comprises drawing the third suture tail and the fourth suture tail through the tube.

11. The method of claim 10 , further comprising pressing a distal end of the suture-holding device against the ventricular side of the heart valve while performing said forming the first knot and said pushing the first knot.

12. The method of claim 10 , wherein the suture-holding device comprises a radially-projecting stopper disposed at a distal end of the suture-holding device.

13. The method of claim 9 , wherein the pushing device comprises one or more radially-projecting prongs configured to engage one or more suture knots.

14. The method of claim 13 , wherein:
the one or more radially-projecting prongs comprises first and second prongs that are aligned and offset with respect to a length of the pushing device;
the method further comprises:
forming a second knot by tying the first suture tail to the second suture tail proximal to the first knot;
engaging the first prong with the first knot; and
engaging the second prong with the second knot; and

said pushing comprises simultaneously pushing the first knot and the second knot with the first prong and the second prong, respectively, by distally pushing the pushing device.

15. The method of claim 9 , wherein the pushing device comprises a shaft having a side window at a distal end portion of the pushing device.

16. The method of claim 15 , wherein the said pushing the first knot is performed using a distal frame portion of the side window.

17. The method of claim 15 , further comprising drawing the first suture tail through the side window prior to said forming the first knot.

Assignees

• Univ Maryland
• Harpoon Medical Inc

Inventors

• Gammie James S
• Wilson Peter
• Boyd Peter
• Niland William

Classifications

• A61B2017/00783

  Valvuloplasty · CPC title

• A61B2090/034

  abutting on parts of the device itself · CPC title

• A61B2017/0488

  Instruments for applying suture clamps, clips or locks · CPC title

• A61B17/0401 Primary

  Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors (A61B17/0642 takes precedence; fixation devices for tendons or ligaments A61F2/0811) · CPC title

• A61B2017/0474

  Knot pushers · CPC title