Methods for PET detector afterglow management

Patent metadata

Field	Value
Publication number	US-11675097-B2
Application number	US-202217697828-A
Country	US
Kind code	B2
Filing date	Mar 17, 2022
Priority date	Jul 11, 2017
Publication date	Jun 13, 2023
Grant date	Jun 13, 2023

Abstract

Disclosed herein are methods and devices for the acquisition of positron emission (or PET) data in the presence of ionizing radiation that causes afterglow of PET detectors. In one variation, the method comprises adjusting a coincidence trigger threshold of the PET detectors during a therapy session. In one variation, the method comprises adjusting a gain factor used in positron emission data acquisition (e.g., a gain factor used to multiply and/or shift the output(s) of a PET detector(s)) during a therapy session. In some variations, a method for acquiring positron emission data during a radiation therapy session comprises suspending communication between the PET detectors and a signal processor of a controller for a predetermined period of time after a radiation pulse has been emitted by the linac.

First claim

The invention claimed is:

1. A radiation therapy system comprising:
a therapeutic radiation source configured to deliver one or more radiation pulses toward a PET-avid region of interest during one or more irradiation intervals;
a plurality of PET detectors configured to detect one or more positron emission paths emitted by the PET-avid region of interest during one or more detection intervals; and
a radiation-blocking filter movable over the plurality of PET detectors, wherein the radiation-blocking filter is configured to be positioned over the plurality of PET detectors during the one or more irradiation intervals and positioned away from the PET detectors during the one or more detection intervals.

2. The system of claim 1 , wherein the radiation-blocking filter is a ring around a bore of the radiation therapy system.

3. The system of claim 2 , wherein the radiation-blocking filter ring is a closed ring.

4. The system of claim 2 , wherein the radiation-blocking filter ring is an open ring.

5. The system of claim 1 , wherein the radiation-blocking filter comprises a first radiation-blocking section and a second radiation blocking section.

6. The system of claim 5 , wherein the first and second radiation-blocking sections of the radiation-blocking filter are mounted on a ring and arranged to correspond with the arrangement of the plurality of PET detectors.

7. The system of claim 6 , wherein the plurality of PET detectors comprise a first PET detector array and a second PET detector array located opposite to the first PET detector array, and the first radiation-blocking section is located opposite to the second radiation-blocking section on the radiation-blocking filter ring.

8. The system of claim 7 , wherein a length of the first radiation-blocking system corresponds with a length of the first PET detector array, and a length of the second radiation-blocking system corresponds with a length of the second PET detector array.

9. The system of claim 5 , wherein the radiation-blocking filter has a first configuration where the first radiation-blocking section and the second radiation-blocking section are disposed over the plurality of PET detectors and a second configuration where the first radiation-blocking section and the second radiation-blocking section are not disposed over the plurality of PET detectors.

10. The system of claim 9 , wherein the plurality of PET detectors comprise a first PET detector array and a second PET detector array located opposite to the first PET detector array on a circular gantry, and the radiation-blocking filter is a ring located within an inner diameter of the circular gantry and the first radiation-blocking section is located opposite to the second radiation-blocking section on the radiation-blocking filter ring, and
wherein rotating the radiation-blocking filter ring within the inner diameter moves the radiation-blocking filter ring between the first configuration and the second configuration.

11. The system of claim 10 , further comprising a motion controller coupled to the radiation-blocking filter ring configured to rotate the radiation-blocking filter ring between the first configuration and the second configuration.

12. The system of claim 9 , wherein the plurality of PET detectors comprise a first PET detector array and a second PET detector array located opposite to the first PET detector array on a circular gantry, and the radiation-blocking filter is a ring located within an inner diameter of the circular gantry and the first radiation-blocking section is located opposite to the second radiation-blocking section on the radiation-blocking filter ring, and
wherein laterally translating the radiation-blocking filter ring into and out of the inner diameter of the gantry moves the radiation-blocking filter ring between the first configuration and the second configuration.

13. The system of claim 12 , wherein the radiation-blocking filter ring is configured to laterally oscillate into and out of the inner diameter of the gantry.

14. The system of claim 12 , wherein the radiation-blocking filter ring is configured to be laterally translated into the inner diameter of the gantry during an irradiation interval and is configured to be laterally translated out of the inner diameter of the gantry during a detection interval.

15. The system of claim 12 , further comprising a motion controller coupled to the radiation-blocking filter ring configured to laterally translate the radiation-blocking filter ring between the first configuration and the second configuration.

16. The system of claim 5 , wherein each of the first and section radiation-blocking sections may comprise one or more panels of a radiation-reflecting and/or radiation-absorbent material.

17. The system of claim 16 , wherein the radiation-reflecting and/or radiation-absorbent material comprises a high-Z material.

18. The system of claim 5 , wherein the radiation-blocking filter ring further comprises radiotransparent sections between the first and second radiation-blocking sections.

19. The system of claim 1 , further comprising a motion controller coupled to the radiation-blocking filter configured to position the radiation-blocking filter relative to the PET detectors.

20. The system of claim 19 , wherein the motion controller comprises an actuator.

Assignees

• Reflexion Medical Inc

Inventors

• Olcott Peter Demetri
• Bieniosek Matthew Francis
• Harper Brent

Classifications

• A61N2005/1052

  using positron emission tomography [PET] single photon emission computer tomography [SPECT] imaging · CPC title

• G01T1/208

  Circuits specially adapted for scintillation detectors, e.g. for the photo-multiplier section · CPC title

• G01T1/172

  with coincidence circuit arrangements (G01T1/178 takes precedence {; combination of detectors, see G01T1/1603, G01T1/30}) · CPC title

• A61N5/1077

  Beam delivery systems · CPC title

• G01T1/2985 Primary

  In depth localisation, e.g. using positron emitters; Tomographic imaging (longitudinal and transverse section imaging; apparatus for radiation diagnosis sequentially in different planes, steroscopic radiation diagnosis); (using external radiation sources A61B6/02) · CPC title