System and method for improved fluid delivery in multi-fluid injector systems

Patent metadata

Field	Value
Publication number	US-11672902-B2
Application number	US-202117157506-A
Country	US
Kind code	B2
Filing date	Jan 25, 2021
Priority date	Mar 3, 2016
Publication date	Jun 13, 2023
Grant date	Jun 13, 2023

Abstract

A method of maintaining an overall flow rate during a sequential delivery of at least two fluids to a patient's blood vessel includes delivering at least a first fluid into the patient's blood vessel at a first flow rate, delivering at least a second fluid into the patient's blood vessel at a second flow rate, and adjusting at least one of a first flow profile of the first flow rate and a second flow profile of the second flow rate to dampen a transient increase in the overall flow rate during a transition between delivering one of the first fluid and the second fluid to delivering the other of the first fluid and the second fluid.

First claim

What is claimed is:

1. A method of maintaining an overall flow rate during a sequential delivery of a first fluid followed by a second fluid, the method comprising:
delivering the first fluid using a powered fluid injector;
delivering the second fluid using the powered fluid injector; and
adjusting at least one of a first flow profile of the first fluid and a second flow profile of the second fluid to dampen a transient change in the overall flow rate during a transition between delivering the first fluid to delivering the second fluid.

2. The method of claim 1 , further comprising delaying the delivering the second fluid until the first fluid reaches a predetermined flow rate.

3. The method of claim 1 , further comprising adjusting one of the first flow profile and the second flow profile based on the other of the first flow profile and the second flow profile.

4. The method of claim 1 , further comprising pressurizing at least one of the first fluid and the second fluid using at least one check valve to a predetermined pressure before delivering the at least one of the first fluid and the second fluid.

5. The method of claim 1 , further comprising over-delivering a predetermined volume of at least one of the first fluid and the second fluid during the delivery of at least one of the first fluid and the second fluid.

6. The method of claim 1 , further comprising diluting one of the first fluid and the second fluid with a predetermined volume of the other of the first fluid and the second fluid.

7. The method of claim 1 , further comprising reducing a capacitance volume of at least one of a first syringe containing the first fluid and a second syringe containing the second fluid to prevent backflow of at least one of the first fluid into the second syringe and the second fluid into the first syringe.

8. The method of claim 7 , wherein reducing the capacitance volume comprises providing a pressure jacket around at least a portion of an exterior of at least one of the first syringe and the second syringe to reduce a capacitance expansion of at least one of the first syringe and the second syringe when the at least one of the first syringe and the second syringe is under pressure.

9. The method of claim 7 , wherein at least one of the first syringe and the second syringe comprises a reduced inner diameter or an obstruction member within an interior of the at least one of the first syringe and the second syringe.

10. The method of claim 1 , wherein the first fluid has a different viscosity than the second fluid.

11. The method of claim 1 , further comprising controlling one of a first flow rate of the first fluid and a second flow rate of the second fluid using an equalizing flow valve based on the other of the first flow rate and the second flow rate.

12. The method of claim 1 , further comprising adjusting at least one of a first flow rate of the first fluid and a second flow rate of the second fluid before delivery of at least one of the first fluid and the second fluid based on at least one of a known operating fluid pressure, a capacitance of the first syringe and the second syringe, and an overall capacitance of the powered fluid injector.

13. The method of claim 1 , further comprising increasing a transition time between delivering the first fluid and delivering the second fluid.

14. A multi-fluid injection system comprising:
a first syringe configured for containing a first fluid;
a second syringe configured for containing a second fluid;
a drive mechanism configured for delivering the first fluid from the first syringe and the second fluid from the second syringe; and
a controller operatively connected to the drive mechanism, wherein the controller is configured to maintain an overall flow rate during a sequential delivery of the first fluid followed by the second fluid, wherein the controller comprises a processor configured to control the multi-fluid injection system to:
deliver the first fluid using the drive mechanism;
deliver the second fluid using the drive mechanism; and
adjust at least one of a first flow profile of the first fluid and a second flow profile of the second fluid to dampen a transient change in the overall flow rate during a transition between delivering the first fluid to delivering the second fluid.

15. The multi-fluid injection system of claim 14 , wherein the processor is further configured to control the multi-fluid injection system to increase a transition time between delivering the first fluid and delivering the second fluid.

16. The multi-fluid injection system of claim 14 , wherein the processor is further configured to control the multi-fluid injection system to delay the delivery of one of the first fluid and the second fluid until the other of the first fluid and the second fluid reaches a predetermined flow rate.

17. The multi-fluid injection system of claim 14 , wherein the processor is further configured to control the multi-fluid injection system to over-deliver a predetermined volume of at least one of the first fluid and the second fluid during delivery of at least one of the first fluid and the second fluid.

18. The multi-fluid injection system of claim 14 , further comprising an equalizing flow valve, wherein the processor is configured to control one of a first flow rate of the first fluid and a second flow rate of the second fluid using the equalizing flow valve based on the other of the first flow rate and the second flow rate.

19. The multi-fluid injection system of claim 14 , wherein the processor is further configured to adjust at least one of a first flow rate of the first fluid and a second flow rate of the second fluid before delivery of at least one of the first fluid and the second fluid based on at least one of a known operating fluid pressure, a capacitance of the first syringe and the second syringe, and an overall capacitance of the multi-fluid injection system.

20. A method for reducing catheter kickback in a patient's vasculature during a transition between delivery of a first fluid and a second fluid, the method comprising:
delivering the first fluid using a powered fluid injector;
delivering the second fluid using the powered fluid injector; and
adjusting at least one of a first flow profile of the first fluid and a second flow profile of the second fluid to dampen a transient increase in an overall flow rate during the transition between delivering the first fluid to delivering the second fluid,
wherein the first fluid and the second fluid have a different viscosity.

Assignees

• Bayer Healthcare Llc

Inventors

• Spohn Michael
• Schriver Ralph
• Uber Iii Arthur
• Heller Ronald
• Cowan Kevin
• Tucker Barry
• Rhinehart Edward
• Newing Timothy

Classifications

• A61M2205/50

  with microprocessors or computers · CPC title

• A61M2005/14553

  comprising a pressure jacket · CPC title

• A61M5/14546 Primary

  Front-loading type injectors · CPC title

• A61M5/1408 Primary

  in parallel, e.g. manifolds, sequencing valves (access sites A61M39/02; tube connectors A61M39/10) · CPC title

• A61M2205/3331

  Pressure; Flow · CPC title