Nerve stimulation apparatus and biomagnetic field measurement system
US-10722701-B2 · Jul 28, 2020 · US
US11666759B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11666759-B2 |
| Application number | US-202017069193-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 13, 2020 |
| Priority date | Oct 16, 2019 |
| Publication date | Jun 6, 2023 |
| Grant date | Jun 6, 2023 |
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A nerve stimulating apparatus includes a plurality of stimulating units configured to respectively apply stimuli to a plurality of nerve regions branching from a particular nerve region of a living body, and a stimulation timing controller configured to set generating timings of respectively generating the stimuli at the plurality of stimulating units. The stimulation timing controller sets the generating timings of generating the stimuli at the plurality of stimulating units based on response results of the particular nerve region, the response results being obtained in response to the stimuli that are respectively generated at the plurality of stimulating units and that are respectively applied to the plurality of nerve regions, and the response results being measured by a biometric information measuring apparatus that measures biometric information.
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What is claimed is: 1. A nerve stimulating apparatus comprising: a plurality of stimulating units configured to respectively apply stimuli to a plurality of nerve regions branching from a particular nerve region of a living body, the stimuli being electrical stimuli, magnetic stimuli, acoustic stimuli, or mechanical stimuli; and a stimulation timing controller configured to set generating timings of respectively generating the stimuli at the plurality of stimulating units, wherein the stimulation timing controller sets the generating timings of generating the stimuli at the plurality of stimulating units based on response results of the particular nerve region, the response results being obtained in response to the stimuli that are respectively generated at the plurality of stimulating units and that are respectively applied to the plurality of nerve regions, and each of the response results being a magnetic field measured by a biomagnetic field measuring device, wherein the stimulation timing controller respectively calculates a plurality of latencies each indicating a duration from when a respective one of the stimuli is applied to the living body to when a corresponding one of feature points appears in a response of the living body, for the plurality of stimulating units, based on current data estimated based on the measured magnetic field, and sets the generating timings based on the plurality of calculated latencies. 2. The nerve stimulating apparatus as claimed in claim 1 , wherein the stimulation timing controller sets the generating timings based on the plurality of calculated latencies so as to cause the feature points to appear at the same time. 3. The nerve stimulating apparatus as claimed in claim 2 , wherein the stimulation timing controller calculates a peak value of a waveform indicating temporal changes of a strength of the response measured by the biomagnetic field measuring device or a rise of the waveform, as each of the feature points. 4. The nerve stimulating apparatus as claimed in claim 2 , wherein the stimulation timing controller is further configured to calculate the generating timings to cause the feature points to appear at the same time based on the plurality of latencies respectively calculated for the plurality of stimulating units, and a trigger signal generator configured to generate a trigger signal based on the calculated generating timings, and wherein the plurality of stimulating units generates the stimuli in response to the trigger signal. 5. The nerve stimulating apparatus as claimed in claim 4 , wherein the trigger signal generator generates a plurality of said trigger signals respectively output to the plurality of stimulating units, and wherein the plurality of stimulating units respectively generates the stimuli in response to the plurality of trigger signals. 6. A biometric information measuring system comprising: a nerve stimulating apparatus including a plurality of stimulating units configured to respectively apply stimuli to a plurality of nerve regions branching from a particular nerve region of a living body, the stimuli being electrical stimuli, magnetic stimuli, acoustic stimuli, or mechanical stimuli; a biomagnetic field measuring device configured to measure response results of the particular nerve region as biometric information, the response results being generated in response to the stimuli respectively applied to the plurality of nerve regions; and a stimulation timing control device configured to set generating timings of respectively generating the stimuli at the plurality of stimulating units, wherein the stimulation timing control device sets the generating timings of generating the stimuli at the plurality of stimulating units based on the response results of the particular nerve region, the response results being obtained in response to the stimuli that are respectively generated at the plurality of stimulating units and that are respectively applied to the plurality of nerve regions, and each of the response results being a magnetic field measured by the biomagnetic field measuring device, wherein the stimulation timing controller respectively calculates a plurality of latencies each indicating a duration from when a respective one of the stimuli is applied to the living body to when a corresponding one of feature points appears in a response of the living body, for the plurality of stimulating units, based on current data estimated based on the measured magnetic field, and sets the generating timings based on the plurality of calculated latencies. 7. The biometric information measuring system as claimed in claim 6 , wherein the stimulation timing control device respectively calculates a plurality of latencies each indicating a duration from when a respective one of the stimuli is applied to the living body to when a corresponding one of feature points appears in a response of the living body, for the plurality of stimulating units, based on the response results of the particular nerve region, and sets the generating timings based on the plurality of calculated latencies so as to cause the feature points to appear at the same time. 8. The biometric information measuring system as claimed in claim 7 , wherein the stimulation timing control device calculates a peak value of a waveform indicating temporal changes of a strength of the response measured by the biomagnetic field measuring device or a rise of the waveform, as each of the feature points. 9. The biometric information measuring system as claimed in claim 7 , wherein the stimulation timing control device is further configured to calculate the generating timings to cause the feature points appear at the same time based on the plurality of latencies respectively calculated for the plurality of stimulating units, and a trigger signal generator configured to generate a trigger signal based on the calculated generating timings calculated, and wherein the plurality of stimulating units generates the stimuli in response to the trigger signal. 10. The biometric information measuring system as claimed in claim 9 , wherein the trigger signal generator generates a plurality of said trigger signals respectively output to the plurality of stimulating units, and wherein the plurality of stimulating units respectively generates the stimulus in response to the plurality of trigger signals. 11. The biometric information measuring system as claimed in claim 10 , wherein the nerve stimulating apparatus includes a plurality of sub-stimulators respectively including the plurality of stimulating units, and wherein the trigger signal generator generates the plurality of trigger signals respectively output to the plurality of stimulating units of the plurality of sub-stimulators. 12. The biometric information measuring system as claimed in claim 6 , wherein the magnetic field is generated by the living body, and wherein the stimuli applied by the plurality of stimulating units to the living body are electrical stimuli. 13. The biometric information measuring system as claimed in claim 12 , further comprising an electric potential measuring device that is configured to measure an electric potential difference at the particular nerve region of the living body, in addition to the biomagnetic field measuring device. 14. A method of setting stimulus generating timings of a biometric information measuring system including a nerve stimulating apparatus including a plurality of stimulating units configured to respectively apply stimuli to a plurality of nerve regions branching from a particular nerve region of a living body, th
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