Biodegradable pressure sensor

Patent metadata

Field	Value
Publication number	US-11666239-B2
Application number	US-201816491614-A
Country	US
Kind code	B2
Filing date	Mar 14, 2018
Priority date	Mar 14, 2017
Publication date	Jun 6, 2023
Grant date	Jun 6, 2023

Abstract

A biodegradable pressure sensor for measuring vital physiological pressures and for preventing the buildup of dangerous internal forces in impaired organs. The pressure sensor is constructed by depositing Mg or Mo on both sides of a PLLA film. This layered configuration (Mg/PLLA/Mg) or (Mo/PLLA/Mo) may then be encapsulated by layers of high molecular weight PLA. These materials are biodegradable such that after implantation, the sensor does not require invasive removal surgery that can damage directly interfaced tissues.

First claim

What is claimed is:

1. A biodegradable system comprising:
one or more magnesium wires encapsulated by poly-lactic acid;
a biodegradable piezoelectric device connected to the one or more magnesium wires, the biodegradable piezoelectric device including
a first magnesium electrode,
a second magnesium electrode, and
a polymer film positioned between the first magnesium electrode and the second magnesium electrode, the polymer film comprisinq a piezoelectric poly-L-lactic acid film,

wherein the biodegradable piezoelectric device is encapsulated by a biodegradable polymer; and
a charcie amplifier circuit connected to the biodegradable piezoelectric device, wherein the charge amplifier circuit is configured to convert a charge from the biodegradable piezoelectric device into a voltage signal and output the voltage signal to an electronic device.

2. The biodegradable system of claim 1 , wherein the biodegradable piezoelectric device includes at least one selected from a group consisting of a biodegradable piezoelectric sensor, a biodegradable piezoelectric actuator, and a biodegradable piezoelectric energy harvester.

3. The biodegradable system of claim 1 , wherein the biodegradable polymer polymer has a molecular weight of at least 200 kDa.

4. The biodegradable system of claim 1 , wherein the biodegradable piezoelectric device has a functional lifetime proportional to at least one selected from a group consisting of an amount of piezoelectric poly-L-lactic acid film layers included in the polymer film and a molecular weight of each piezoelectric poly-L-lactic acid film layer included in the polymer film.

5. The biodegradable system of claim 4 , wherein the functional life time of the biodegradable piezoelectric device increases as the amount or thickness of poly-lactic acid film layers encapsulating the sensor increases.

6. The biodegradable system of claim 4 , wherein the functional life time of the biodegradable piezoelectric device increases as the molecular weight of each encapsulating poly-lactic acid film layers included in the sensor increases.

7. The biodegradable system of claim 1 , wherein the polymer film includes two layers of a piezoelectric poly-L-lactic acid film.

8. The biodegradable system of claim 1 , wherein the biodegradable piezoelectric device is configured to function as a sensitive multi-layer pressure transducer.

9. The biodegradable system of claim 1 , wherein the biodegradable piezoelectric device is configured to output a charge in response to a pressure applied to the biodegradable piezoelectric device.

10. The biodegradable system of claim 1 , wherein the biodegradable piezoelectric device has a size of approximately 0.5×0.5×0.02 cm.

11. The biodegradable system of claim 1 , wherein the biodegradable piezoelectric device is configured to sense pressure within a range of approximately 1-50 mmHg.

12. A biodegradable system comprising:
one or more molybdenum wires encapsulated by poly-lactic acid;
a biodegradable piezoelectric device connected to the one or more molybdenum wires, the biodegradable piezoelectric device including
a first molybdenum electrode,
a second molybdenum electrode, and
a polymer film positioned between the first molybdenum electrode and the second molybdenum electrode, the polymer film comprising a piezoelectric poly-L-lactic acid film,

wherein the biodegradable piezoelectric device is encapsulated by a biodegradable polymer; and
a charge amplifier circuit connected to the biodegradable piezoelectric device, wherein the charge amplifier circuit is configured to convert a charge from the biodegradable piezoelectric device into a voltage signal and output the voltage signal to an electronic device.

13. The biodegradable system of claim 12 , wherein the biodegradable piezoelectric device includes at least one selected from a group consisting of a biodegradable piezoelectric sensor, a biodegradable piezoelectric actuator, and a biodegradable piezoelectric energy harvester.

14. The biodegradable system of claim 12 , wherein the biodegradable polymer has a molecular weight of at least 200 kDa.

15. The biodegradable system of claim 12 , wherein the biodegradable piezoelectric device has a functional lifetime proportional to at least one selected from a group consisting of an amount of piezoelectric poly-L-lactic acid film layers included in the polymer film and a molecular weight of each piezoelectric poly-L-lactic acid film layer included in the polymer film.

16. The biodegradable system of claim 15 , wherein the functional life time of the biodegradable piezoelectric device increases as the amount or thickness of poly-lactic acid film layers encapsulating the sensor increases.

17. The biodegradable system of claim 15 , wherein the functional life time of the biodegradable piezoelectric device increases as the molecular weight of each encapsulating poly-lactic acid film layers included in the sensor increases.

18. The biodegradable system of claim 12 , wherein the polymer film includes two layers of a piezoelectric poly-L-lactic acid film.

19. The biodegradable system of claim 12 , wherein the biodegradable piezoelectric device is configured to function as a sensitive multi-layer pressure transducer.

20. The biodegradable system of claim 12 , wherein the biodegradable piezoelectric device is configured to output a charge in response to a pressure applied to the biodegradable piezoelectric device.

21. The biodegradable system of claim 12 , wherein the biodegradable piezoelectric device has a size of approximately 0.5×0.5×0.02 cm.

22. The biodegradable system of claim 12 , wherein the biodegradable piezoelectric device is configured to sense pressure within a range of approximately 1-50 mmHg.

Assignees

• Univ Connecticut

Inventors

• Nguyen Thanh Duc
• Curry Eli

Classifications

• A61B5/6867

  specially adapted to be attached or implanted in a specific body part (A61B5/6847 takes precedence) · CPC title

• A61B5/031 Primary

  Intracranial pressure · CPC title

• A61B2562/0209

  Special features of electrodes classified in A61B5/24, A61B5/25, A61B5/283, A61B5/291, A61B5/296, A61B5/053 · CPC title

• A61L2420/08

  Coatings comprising two or more layers · CPC title

• A61B2562/04

  Arrangements of multiple sensors of the same type · CPC title