Syringe and prefilled syringe

Patent metadata

Field	Value
Publication number	US-11660402-B2
Application number	US-202016862874-A
Country	US
Kind code	B2
Filing date	Apr 30, 2020
Priority date	Oct 31, 2017
Publication date	May 30, 2023
Grant date	May 30, 2023

Abstract

In a syringe, which is a prefilled syringe, when a cap body is attached to a cylindrical portion, a first sealing section is compressed radially inward by an inner peripheral surface constituting an opening of the cylindrical portion, thereby sealing a distal end section of a flow path in a liquid-tight manner, and a second sealing section is compressed radially inward by an inner peripheral surface of a proximal end section of the cylindrical portion, thereby sealing a proximal end section of the flow path in a liquid-tight manner.

First claim

What is claimed is:

1. A syringe, the syringe comprising:
a barrel body including a body portion that is hollow and configured to be filled with a drug solution, and a cylindrical portion that protrudes in a distal direction from a distal end of the body portion and includes an opening at a distal end of the cylindrical portion, the cylindrical portion defining a flow path that connects an inside of the body portion and the opening;
a cap including a cap body that is configured to be attached to the cylindrical portion, the cylindrical portion includes a female luer section having an inner diameter reduced in a proximal direction from the opening and configured to be engageable with a male luer section of another medical device, and a proximal end section that connects the female luer section to the body portion;
the cap body includes a base located closer to the distal end than the opening in a state where the cap body is attached to the cylindrical portion, and an insertion portion that protrudes from the base in a proximal direction and configured to be inserted into the cylindrical portion;
the insertion portion of the cap body includes a first sealing section provided at a distal end of the insertion portion and having an outer diameter greater than a diameter of the opening in a natural state where the cap body is not attached to the cylindrical portion, and a second sealing section provided at a proximal end of the insertion portion and having an outer diameter greater than an inner diameter of the proximal end section of the cylindrical portion in the natural state;
when the cap body is attached to the cylindrical portion, the first sealing section is configured to seal a distal end section of the flow path in a liquid-tight manner by being compressed radially inward by an inner peripheral surface constituting the opening of the cylindrical portion, and the second sealing section is configured to seal a proximal end section of the flow path in a liquid-tight manner by being compressed radially inward by an inner peripheral surface of the proximal end section of the cylindrical portion;
the proximal end section of the cylindrical portion includes an annular protruding section, the inner peripheral surface of the proximal end section protruding radially inward and configured to compress the second sealing section radially inward;
the cap body includes an expanded portion on a proximal end of the second sealing section, the expanded portion having an outer diameter greater than an outer diameter of the second sealing section; and
when the cap body is attached to the cylindrical portion, a distal end of the expanded portion is configured to be engageable with a proximal end of the annular protruding section.

2. The syringe according to claim 1 , wherein
the cap body has a proximal-end protruding portion protruding in the proximal direction from the insertion portion; and
when the cap body is attached to the cylindrical portion, the proximal-end protruding portion is configured to be disposed within a distal end section of the body portion.

3. The syringe according to claim 2 , wherein the proximal-end protruding portion protrudes toward a proximal end in a tapered manner.

4. The syringe according to claim 1 , wherein the cap body includes, between the first sealing section and the second sealing section, an intermediate section having an outer diameter smaller than an inner diameter of the female leer section.

5. The syringe according to claim 4 , wherein the cap body includes, between the intermediate section and the second sealing section, a third sealing section having an outer diameter greater than an inner diameter of the cylindrical portion in the natural state, and the third sealing section configured to seal the flow path in a liquid-tight manner by being compressed radially inward by the inner peripheral surface of the cylindrical portion.

6. The syringe according to claim 1 , wherein the cap further comprises:
a cylindrical cover member, the cover member being made of a material harder than the cap body and having an engagement portion to be engaged with the base of the cap body; and
the cover member is configured to be attachable to the cap body so as to cover at least a part of an outer peripheral surface of the base due to an engagement between the engagement portion and the base.

7. The syringe according to claim 6 , wherein the cover member comprises:
a cylindrical first cover portion, the first cover portion having the engagement portion and covering the outer peripheral surface of the base; and
a second cover portion that extends in a proximal direction from the first cover portion and that covers an outer peripheral surface of the cylindrical portion.

8. The syringe according to claim 7 , wherein the second cover portion has a female screw section on an inner peripheral surface, and the cylindrical portion has a screw portion that is screwed to the female screw section on the outer peripheral surface.

9. The syringe according to claim 1 , wherein the cap body is made of an elastic material.

10. A syringe, the syringe comprising:
a barrel body including a body portion that is hollow and configured to be filled with a drug solution, and a cylindrical portion that protrudes in a distal direction from a distal end of the body portion and includes an opening at a distal end of the cylindrical portion, the cylindrical portion defining a flow path that connects an inside of the body portion and the opening;
a cap including a cap body that is configured to be attached to the cylindrical portion, the cylindrical portion includes a female luer section having an inner diameter reduced in a proximal direction from the opening and configured to be engageable with a male luer section of another medical device, and a proximal end section that connects the female luer section to the body portion;
the cap body includes a base located closer to the distal end than the opening in a state where the cap body is attached to the cylindrical portion, and an insertion portion that protrudes from the base in a proximal direction and configured to be inserted into the cylindrical portion;
the insertion portion of the cap body includes a first sealing section provided at a distal end of the insertion portion and having an outer diameter greater than a diameter of the opening in a natural state where the cap body is not attached to the cylindrical portion, and a second sealing section provided at a proximal end of the insertion portion and having an outer diameter greater than an inner diameter of the proximal end section of the cylindrical portion in the natural state;
when the cap body is attached to the cylindrical portion, the first sealing section seals a distal end section of the flow path in a liquid-tight manner by being compressed radially inward by an inner peripheral surface constituting the opening of the cylindrical portion, and the second sealing section seals a proximal end section of the flow path in a liquid-tight manner by being compressed radially inward by an inner peripheral surface of the proximal end section of the cylindrical portion;
the proximal end section of the cylindrical portion has an annular recess, the inner peripheral surface of the proximal end section being recessed radially outward;
the second sealing section having an outer diameter greater than an inner diameter of the annular recess;
the insertion portion having a reduced portion at a distal end of the second sealing section, the reduced portion having an outer diameter smaller than an outer diameter of the second sealing section; and
when the cap body is attached to the cylindrical portion, the second sealing section

Assignees

• Terumo Corp

Inventors

• Okihara Hitoshi

Classifications

• A61M2005/312

  comprising sealing means, e.g. severable caps, to be removed prior to injection by, e.g. tearing or twisting · CPC title

• A61M5/3202 Primary

  Devices for protection of the needle before use, e.g. caps (A61M5/50 takes precedence; for infusion spikes A61M5/1626; protectors for sharps A61B50/3001) · CPC title

• A61M2005/3109

  Caps sealing the needle bore by use of, e.g. air-hardening adhesive, elastomer or epoxy resin · CPC title

• A61M5/31

  Details · CPC title

• A61M39/20

  Closure caps or plugs for connectors or open ends of tubes · CPC title