Physiological measurement using wearable device

Patent metadata

Field	Value
Publication number	US-11657916-B2
Application number	US-201916665733-A
Country	US
Kind code	B2
Filing date	Oct 28, 2019
Priority date	Jun 21, 2013
Publication date	May 23, 2023
Grant date	May 23, 2023

Abstract

A method for real-time, high-density physiological data collection includes automatically measuring, by a wearable device, one or more physiological parameters during each of a plurality of measurement periods, and upon conclusion of a measurement period, for each of the plurality of measurement periods, automatically transmitting by the wearable device data representative of the physiological parameters measured during that measurement period, to a server, the server configured to develop a baseline profile based on the data transmitted by the wearable device for the plurality of measurement periods. The measurement periods may extend through a plurality of consecutive days, and each of the consecutive days may include multiple measurement periods. At least some of the physiological parameters are measured by non-invasively detecting one or more analytes in blood circulating in subsurface vasculature proximate to the wearable device.

First claim

What is claimed is:

1. A method, comprising:
measuring, by a wearable device being worn on an external surface of a body of a user proximate a portion of subsurface vasculature, one or more physiological parameters during one or more measurement periods to develop a baseline profile of the user, wherein the one or more physiological parameters are measured by:
directing, from a magnet in the wearable device, a magnetic field into the portion of subsurface vasculature, wherein the magnetic field causes functionalized magnetic particles that have been introduced into the body to collect in a lumen of the portion of subsurface vasculature;
directing, from a signal source in the wearable device, an interrogating signal into the portion of subsurface vasculature; and
detecting, by a detector in the wearable device, a response signal transmitted from the portion of subsurface vasculature in response to the interrogating signal, wherein the response signal is indicative of binding of one or more analytes to the functionalized magnetic particles collected in the lumen of the subsurface vasculature by the magnetic field;

measuring, using the magnet, signal source, and detector in the wearable device, the one or more physiological parameters during one or more additional measurement periods to obtain additional data; and
providing, by the wearable device, an output based on the additional data deviating from the baseline profile.

2. The method of claim 1 , wherein the output is provided via a user interface of the wearable device.

3. The method of claim 2 , wherein the output comprises at least one of a visual component, an auditory component, or a tactile component.

4. The method of claim 3 , wherein the output indicates one or more recommendation for the user.

5. The method of claim 4 , wherein the one or more recommendations comprise at least one of a recommendation that the user take a particular medication, a recommendation that the user schedule an appointment with a medical professional, a recommendation that the user seek immediate medical attention, or a recommendation that the user abstain from an activity.

6. The method of claim 4 , further comprising:
transmitting, by the wearable device to a server, data indicative of the one or more physiological parameters measured during the one or more measurement periods; and
transmitting, by the wearable device to the server, data indicative of the one or more physiological parameters measured during the one or more additional measurement periods.

7. The method of claim 6 , further comprising:
receiving, by the wearable device from the server, the one or more recommendations.

8. A wearable device, comprising:
a magnet;
a signal source;
a detector;
a processor;
a user interface; and
a non-transitory computer-readable medium having stored therein instructions that are executable by the processor to cause the wearable to perform functions comprising:
measuring one or more physiological parameters of a user of the wearable device during one or more measurement periods to develop a baseline profile of the user, wherein the wearable device is worn on an external body surface of the user proximate a portion of subsurface vasculature, wherein the one or more physiological parameters are measured by:
directing, from the magnet, a magnetic field into the portion of subsurface vasculature, wherein the magnetic field causes functionalized magnetic particles that have been introduced into the body to collect in a lumen of the portion of sub surface vasculature;
directing, from the signal source, an interrogating signal into the portion of subsurface vasculature; and
detecting, by the detector, a response signal transmitted from the portion of subsurface vasculature in response to the interrogating signal, wherein the response signal is indicative of binding of one or more analytes to the functionalized magnetic particles collected in the lumen of the subsurface vasculature by the magnetic field;

measuring, using the magnet, signal source, and detector, the one or more physiological parameters during one or more additional measurement periods to obtain additional data; and
providing an output based on the additional data deviating from the baseline profile.

9. The wearable device of claim 8 , wherein the output is provided via the user interface.

10. The wearable device of claim 9 , wherein the output comprises at least one of a visual component, an auditory component, or a tactile component.

11. The wearable device of claim 10 , wherein the output indicates one or more recommendations for the user.

12. The wearable device of claim 11 , wherein the one or more recommendations comprise at least one of a recommendation that the user take a particular medication, a recommendation that the user schedule an appointment with a medical professional, a recommendation that the user seek immediate medical attention, or a recommendation that the user abstain from an activity.

13. The wearable device of claim 11 , wherein the wearable device further comprises a communication interface, and wherein the functions further comprise:
transmitting, via the communication interface and to a server, data indicative of the one or more physiological parameters measured during the one or more measurement periods; and
transmitting, via the communication interface and to the server, data indicative of the one or more physiological parameters measured during the one or more additional measurement periods.

14. The wearable device of claim 13 , wherein the functions further comprise:
receiving, via the communication interface and from the server, the one or more recommendations.

15. A non-transitory computer readable medium having stored therein instructions that are executable by a processor in a wearable device to cause the wearable device to perform functions comprising:
measuring, by the wearable device, one or more physiological parameters of a user of the wearable device during one or more measurement periods to develop a baseline profile of the user, wherein the wearable device is worn on an external body surface of the user proximate a portion of subsurface vasculature, wherein the one or more physiological parameters are measured by:
directing, from a magnet in the wearable device, a magnetic field into the portion of subsurface vasculature, wherein the magnetic field causes functionalized magnetic particles that have been introduced into the body to collect in a lumen of the portion of sub surface vasculature;
directing, from a signal source in the wearable device, an interrogating signal into the portion of subsurface vasculature; and
detecting, by a detector in the wearable device, a response signal transmitted from the portion of subsurface vasculature in response to the interrogating signal, wherein the response signal is indicative of binding of one or more analytes to the functionalized magnetic particles collected in the lumen of the subsurface vasculature by the magnetic field;

measuring, using the magnet, signal source, and detector in the wearable device, the one or more physiological parameters during one or more additional measurement periods to obtain additional data; and
providing an output based on the additional data deviating from the baseline profile.

16. The non-transitory computer readable medium of claim 15 , wherein the output is provided via a user interface of the wearable device.

17. The non-transitory computer readable medium of claim 16 , wherein the output comprises at least one of a visual component

Assignees

• Verily Life Sciences Llc

Inventors

• Conrad Andrew
• Peeters Eric

Classifications

• A61B5/0022

  Monitoring a patient using a global network, e.g. telephone networks, internet · CPC title

• A61B5/0515

  Magnetic particle imaging · CPC title

• A61N2/002

  in combination with another treatment · CPC title

• A61B5/14503

  invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors (A61B5/1459, A61B5/1464, A61B5/1473, A61B5/1482, A61B5/14865 take precedence) · CPC title

• A61B5/1455

  using optical sensors, e.g. spectral photometrical oximeters · CPC title