Pulmonary artery pressure change monitor

Patent metadata

Field	Value
Publication number	US-11647978-B2
Application number	US-202017102838-A
Country	US
Kind code	B2
Filing date	Nov 24, 2020
Priority date	Nov 25, 2019
Publication date	May 16, 2023
Grant date	May 16, 2023

Abstract

The present disclosure describes systems, methods, and devices to infer changes in pulmonary artery pressure in a subject using Doppler radar. A portable, non-invasive device for non-invasively measuring right ventricular cardiac motion that can be used in a subject's home can infer pulmonary artery pressure changes to increase patient compliance and mitigate the likelihood of heart decompensation. A mobile pulmonary artery pressure monitor can be especially useful to patients with congestive heart failure who are elderly, incapacitated, or do not have easy access to a clinic, doctor's office, or hospital.

First claim

What is claimed is:

1. A method of detecting a heart failure condition in a heart in a body of a subject, comprising:
a) obtaining a first average motion depth of a right ventricle of the heart over a first time period of detection, wherein the first average motion depth is based on an analysis of a first electromagnetic signal that enters the body of the subject from outside the body, is reflected off the right ventricle of the heart, exits the body, and is then detected outside the body;
b) obtaining a second average motion depth of the right ventricle of the heart over a second time period of detection, wherein the second average motion depth is based on an analysis of a second electromagnetic signal that enters the body of the subject from outside the body, is reflected off the right ventricle of the heart, exits the body, and is then detected outside the body;
c) determining a change between the first average motion depth of the first motion average depth of the right ventricle of the heart over the first time period of detection and the second average motion depth of the second average motion depth of the right ventricle of the heart over the second time period of detection; and
d) determining, based on the change between the first average motion depth of the first motion average depth of the right ventricle of the heart over the first time period of detection and the second average motion depth of the second motion average depth of the right ventricle of the heart over the second time period of detection, whether the subject has the heart failure condition,
wherein the heart failure condition comprises decompensated heart failure,
wherein the first electromagnetic signal and the second electromagnetic signal are radio waves.

2. The method of claim 1 , wherein the first time period of detection is a single heartbeat of the subject.

3. The method of claim 1 , wherein the second time period of detection is a single heartbeat of the subject.

4. The method of claim 1 , wherein the heart failure condition further comprises acute decompensated heart failure.

5. The method of claim 1 , wherein the heart failure condition further comprises congestive heart failure.

6. The method of claim 1 , wherein the heart failure condition further comprises fluid accumulation in the heart.

7. The method of claim 1 , wherein the heart failure condition further comprises right-sided heart failure.

8. The method of claim 1 , wherein the heart failure condition further comprises left-sided heart failure.

9. The method of claim 1 , wherein the heart failure condition further comprises systolic heart failure.

10. The method of claim 1 , wherein the heart failure condition further comprises diastolic heart failure.

11. The method of claim 1 , wherein the heart failure condition further comprises Stage A heart failure.

12. The method of claim 1 , wherein the heart failure condition further comprises Stage B heart failure.

13. The method of claim 1 , wherein the heart failure condition further comprises Stage C heart failure.

14. The method of claim 1 , wherein the heart failure condition further comprises Stage D heart failure.

15. The method of claim 1 , wherein the subject is human.

16. The method of claim 1 , wherein the first average magnitude of the first average motion depth of the right ventricle is a first average amplitude of contraction of the right ventricle, wherein the second average motion depth of the right ventricle is a second average amplitude of contraction of the right ventricle.

17. The method of claim 1 , wherein the first average magnitude of the first average motion depth of the right ventricle is a first average amplitude of expansion of the right ventricle, wherein the second average motion depth of the right ventricle is a second average amplitude of expansion of the right ventricle.

18. The method of claim 1 , wherein the change between the first average motion depth of the right ventricle of the heart over the first time period of detection and the second average motion depth of the right ventricle of the heart over the second time period of detection is associated with a pulmonary artery pressure that is associated with the heart failure condition.

19. The method of claim 1 , wherein the change between the first average depth of the right ventricle of the heart over the first time period of detection and the second average motion depth of the right ventricle of the heart over the second time period of detection is a decrease.

20. The method of claim 19 , wherein the decrease between the first average motion depth of the right ventricle of the heart over the first time period of detection and the second average motion depth of the right ventricle of the heart over the second time period of detection indicates an increase in the pulmonary artery pressure in the subject.

21. The method of claim 1 , wherein the change between the first average magnitude of the first average motion depth of the right ventricle of the heart over the first time period of detection and the second average motion depth of the right ventricle of the heart over the second time period of detection is an increase.

22. The method of claim 21 , wherein the increase between the first average motion average depth of the right ventricle of the heart over the first time period of detection and the second average motion depth of the right ventricle of the heart over the second time period of detection indicates a decrease in the pulmonary artery pressure in the subject.

Assignees

• Cardiac Motion Llc
• Univ California

Inventors

• Gao Xiaomeng
• Jiang Xiaonan
• Liu Xiaoguang
• Matthews Dennis
• Schaefer Saul

Classifications

• A61B5/361

  Detecting fibrillation · CPC title

• A61B8/5207

  involving processing of raw data to produce diagnostic data, e.g. for generating an image · CPC title

• A61B8/04 Primary

  Measuring blood pressure · CPC title

• A61B8/08

  Clinical applications (A61B8/02, A61B8/04, A61B8/06 take precedence) · CPC title

• A61B5/1102 Primary

  Ballistocardiography · CPC title